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Table 3 Comparison of the baseline characteristics at the two groups

From: Early versus delayed enteral nutrition for neonatal hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia: a randomized controlled trial

 

EEN group(N = 42)

DEN group

(N = 38)

T/Z/χ2

p-value

Laboratory results

 Blood gas within 1 hour after birth a,b

  Blood lactic acid (mmol/L)

5.20 (3.40,6.25)

5.25 (3.25,7.63)

0.432

0.666

  Base deficit (mmol/L)

−11.15 (− 12.85,-8.18)

−7.40 (− 10.03,-4.55)

−0.986

0.324

  pH

7.03 (6.95,7.17)

7.09 (7.00,7.24)

0.888

0.375

 Blood gas at admission a

  Blood lactic acid (mmol/L)

5.20 (3.40,6.25)

5.25 (3.25,7.63)

0.106

0.916

  Base deficit (mmol/L)

−6.20 (−8.28,-3.68)

−7.40 (−10.03,-4.55)

−1.508

0.132

  pH

7.34 (7.31,7.39)

7.32 (7.26,7.42)

−1.201

0.230

 Blood sugar at admission (mmol/L) b

4.05 (3.20,5.93)

4.55 (3.70,6.28)

1.364

0.173

 Traditional markers of inflammation at admission, n (%)

  Leukocyte< 5 or > 30 (*109/L)

4 (9.52)

2(5.26)

 

0.678 c

  CRP > 8 mg/l

1 (2.38)

0(0.00)

 

1.000 c

  PCT > 0.5 ng/ml

21 (50.00)

19 (50.00)

0.000

1.000

  Neutrophil percentage > 80%

7 (16.67)

5 (13.16)

0.193

0.661

Adjuvant therapy, n (%)

 PICC for least 3 days

4 (9.52)

5 (13.16)

 

0.729 c

 Antibiotics for least one dose

38 (90.48)

35 (92.11)

 

1.000 c

 Vasoactive drug for least 2 hours

16 (38.10)

10 (26.32)

1.262

0.261

  1. CRP C-reactive protein, PCT Procalcitonin, MV Mechanical ventilation, PICC Peripherally inserted central catheters
  2. a Only 46 (57.5%) infants had blood gas data within 1 hour after birth and analyzed for this variable
  3. b Median and interquartile range
  4. c Fisher’ exact test