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Table 2 Literature review regarding the use of RADTs in the pediatric ED

From: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antigen detection in the Emergency Department: data from a pediatric cohort during the fourth COVID-19 wave in Italy

Authors

Type of study

Type of RADT

Number of Patients

Sensitivity

(%)

Specificity

(%)

Denina et al. [9]

retrospective

LumiraDx TM Platform

191

94.1

91.9%

Ollier et. al. [6]

prospective

Biospeedia antigen test

1009

69.9%

99.9%

Jung et al. [10]

prospective

Biosynex COVID-19 Ag BSS

308

87.9%

98.5%

Carbonell -Sahuquillo et al. [3]

prospective

PanbioTM COVID-19 Ag Rapid Test Device

357

70.5%

100%

Villaverde et al. [5]

retrospective, multicenter

Panbio COVID-19 Ag Rapid Test Device (Abbott Rapid Diagnostic)

1620

45.4%

99.8%

Reichert et al. [4]

prospective

SD BioSensor Inc., Suwon, South Korea

710

75%

99.4%

González-Donapetry et al. [11]

prospective

Abbott Rapid Diagnostics Jena GmbH, Jena, Germany

440

77.78%

100%

Lanari et al. [12]

prospective (using 2 types of RAD kit)

COVID-19 Ag Fia Kit

AFIAS COVID-19 Ag kit

386

792

53.8%

86.4%

99.7%

98.3%

Mockel et al. [13]

prospective

Roche SARS-CoV-2 rapid antigen test, Penzberg, Germany

202

72%

99.4%