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Table 3 Distribution of the SCN1A-A3184G genotypes and alleles among the study groups

From: Polymorphisms of the sodium voltage-gated channel, alpha subunit 1 (SCN1A -A3184G) gene among children with non-lesional epilepsy: a case-control study

 

Control group (n = 163)

AEDs-resistant (n = 163)

AEDs- responders (n = 163)

p values

 

OR (95%CI)

Genotypes (n)

 AG

133(81.6)

120(73.6)

124(76.1)

0.214

p1 = 0.08

1.59(0.94–2.69)

 AA

30(18.4)

43(26.4)

39(23.9)

 

p2 = 0.223

1.39(0.816–2.38)

p3 = 0.61

0.88(0.53–1.44)

Alleles (2n)

 A

193(59.2)

206(63.2)

202(61.9)

0.563

p1 = 0.296

0.845(0.617–1.16)

 G (r)

133(40.8)

120(36.8)

124(38.04)

 

p2 = 0.471

0.891(0.651–1.22)

p3 = 0.746

1.05(0.767–1.45)

  1. Data were presented as numbers (percent) and analyzed by the chi-square test
  2. AEDs Antiepileptic Drugs, CI Confidence Interval, N Number, OR Odds Ratio, P Probability, P1 for controls versus AEDs-resistant group, P2 for controls versus AEDs- responders, P3 for AEDs-resistant group versus AEDs- responders