Fig. 1
From: Lingual laser frenotomy in newborns with ankyloglossia: a prospective cohort study
Perioperative Pain Intensity Curve. The current figure summarizes the variations in newborns’ pain intensity throughout the perioperative period (before surgery, during laser frenotomy, immediately after surgery, and thirty minutes after the end of surgery). The mean difference between each time-point and the following is statistically significant (p < .001). Abbreviations: C.R.I.E.S. Cry—Requires Oxygen—Increased Vital Signs—Facial Expression – Sleeplessness