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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: Type D lymphomatoid papulosis with pityriasis lichenoides et varioliformis acuta-like features in a child with parvovirus infection: a controversial diagnosis in the spectrum of lymphoid proliferations: case report and literature review

Fig. 2

Histology: At lower magnification (Panel a: HE, 100x) a “PLEVA-like” pattern is apparent, with a dense, wedge shaped lymphoid infiltrate featuring epidermotropism and morphologically comprising pleomorphic and blastic cells (Panel a inset: HE 400x). The pattern of infiltration is highlighted by immunohistochemical stains, which prove the process to feature a CD8+/CD30 + phenotype (Panel b: CD8, 100x; Panel c: CD30, 100x), the latter being intense on larger cells (Panel c inset: CD30, 400x), with antigenic loss (Panel d: CD2, 100x; Panel e: CD3, 100x; Panel f: CD5, 100x). GeneScan analysis (Panel g) depicts a monoclonal TCRG peak

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Italian Journal of Pediatrics

ISSN: 1824-7288

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