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Table 4 Receiver operating characteristic (ROC) curves analysis of selected parameters as predictors of the acute phase of urticaria

From: Assessment of selected interleukins (IL-6, IL-17A, IL-18, IL-23) and chemokines (RANTES, IP-10) in children with acute and chronic urticaria

Parameter

AUC

95% AUC CI

Cut-off

Sensitivity %

Specificity %

Youden index

p

IP-10

0.98

0.95–1.00

55.10

92

100

0.9219

< 0.001

IL-6

0.96

0.92–1.00

9.85

92

100

0.9219

< 0.001

IL-23

0.96

0.93–0.99

481.00

86

98

0.8344

< 0.001

RANTES

0.92

0.87–0.97

5241.00

92

83

0.7469

< 0.001

IL-17A

0.88

0.81–0.95

38.20

78

88

0.6563

< 0.001

IL-18

0.79

0.70–0.88

123.90

70

75

0.4531

< 0.001

  1. AUC area under curve, 95% AUC CI lower and upper limits of the 95% confidence interval for AUC, RANTES Regulated upon Activation Normal T-cell Expressed and Secreted, IP-10 IFN-γ-inducible protein-10