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Fig. 3 | Italian Journal of Pediatrics

Fig. 3

From: SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease

Fig. 3

SIGIRR overexpression rescued endothelial cell apoptosis. A-F The protein expression levels of SIGIRR, TLR4, cleaved caspase-8 and cleaved caspase-3, and BAX/Bcl-2 ratio were determined in the treated endothelial cells by Western blotting. G The apoptotic percentage of endothelial cells was analyzed using flow cytometry. The histogram was the quantitative analysis of Annexin V-FITC-positive cells. Data were expressed as mean ± SD (n = 3).* P < 0.05 versus HC group, and # P < 0.05 versus KD group

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