Fig. 4
From: SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease
SIGIRR mitigated endothelial cell apoptosis via inhibiting caspase-8 activity. A The apoptotic percentage of endothelial cells was analyzed using flow cytometry. B-G The protein expression levels of SIGIRR, TLR4, cleaved caspase-8 and cleaved caspase-3, and BAX/Bcl-2 ratio were determined in the treated endothelial cells by Western blotting. * P < 0.05 versus HC group, # P < 0.05 versus KD group, and & P < 0.05 versus KD + AAV-SIGIRR group