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Table 1 Microbiological (treponemal and non-treponemal tests, Immunoblotting, T. pallidum DNA PCR) profiles of our patient and her mother during pregnancy and after delivery

From: Congenital syphilis in a preterm newborn with gastrointestinal disorders and postnatal growth restriction

 

TPHA

VDRL (RPR)

Liaison (UA/ml)

Immunoblotting IgG/IgM

T. pallidum DNA PCR

Mother

 8th week of pregnancy

Negative

Negative

   

 9th week of pregnancy

1:280

Positive (not quantified, performed in a different analysis center)

46.8

  

 12th week of pregnancy

1:640

Positive (not quantified, performed in a different analysis center)

   

 20 days after delivery

1:40,960

1:64

   

 2 months and 16 days after delivery and the administration of three I.M. doses (1,200,000 IU) of Benzathine Benzylpenicillin

 

1:16

45.4

Present/Present

 

 5 months after delivery

 

1:2

   

Daughter

 Day 1

 

1:256

43.4

Present/Present

Positive

 2 months and 12 days

 

1:64

13.0

Present/Present

 

 5 months and 18 days

 

1:4

20.7

Present/Absent

 
  1. I.M. Intramuscular, TPHA Treponema Pallidum Haemagglutination Assay, VDRL Venereal Disease Reference Laboratory, RPR Rapid Plasma Reagin