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Table 5 Specialized infant formulas suitable for patients with gastrointestinal disorders

From: Congenital syphilis in a preterm newborn with gastrointestinal disorders and postnatal growth restriction

Type of infant formula

Clinical indications

Lactose-free infant formulas

Lactose intolerance for congenital lactase deficiency (very rare) or transient lactose deficiency due to acute gastroenteritis (especially for malnourished infants)

Partially hydrolyzed cow’s milk formulas

Easily digested by reducing transit time and gastrointestinal distress for infants experiencing fussing, colic and constipation

Extensively hydrolyzed cow’s milk protein formulas (eHF)

Recommended for cow’s milk/soy protein intolerance and sensitivity and for gastrointestinal or hepatobiliary disease–related significant malabsorption

Amino acid formulas

Use warranted in infants who do not tolerate eHF as well as for diseases like protein malabsorption, gastrointestinal tract motility issues, short bowel syndrome, severe food allergies, and eosinophilic gastroenteropathies