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Table 1 Characteristics of included studies

From: Corticosteroid in anti-inflammatory treatment of pediatric acute myocarditis: a systematic review and meta-analysis

Study

Yr

Type of study

Sample size

Study Duration

Age, Yrs

Treatment

Comparator

Aziz et al

2010

RCT

68

3 months

3.7

Prednisone 2 mg/kg/day for 15 days

Anti-failure medication

Camargo et al

1995

RCT

43

12 months

2.9 (Median)

Conventional therapy with various combinations of corticosteroids

Conventional therapy only—digitalis (Digoxin 10 Ixg/kg/day), diuretics (furosemide 1–4 mg/kg/day), and vasodilators (captopril 0.75–1.5 mg/kg/day)

English et al

2004

Single center retrospective study

41

N/A

2.2 (Median)

Steroid doses ranged from 2 to 10 mg/kg/day for a minimum of 3 days

N/A

Lin et al

2019

Multicenter retrospective study

312

N/A

2.9

Intravenous prednisolone used at > 10 mg/kg/day (steroids alone)

N/A

Saji et al

2012

Multicenter retrospective study

14

N/A

Between 1 month and 17 years

oral prednisolone (1–2 g/kg/day) or intravenous methylprednisolone pulse therapy

N/A

Yang et al

2006

RCT

132

3 months

7.5

Dexamethasone 0.2 mg/kg/day in week 1, 0.15 mg/kg/day in week 2, 0.075 mg/kg/day in week 3; together with ShenMai injection 0.4 ml/kg/day for 10 days

Conventional therapy (unclear)

  1. Abbreviations: RCT Randomized clinical trial, N/A Not available