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Table 1 Characteristics of study sample

From: Adverse drugs reactions to paracetamol and ibuprofen in children: a 5-year report from a pediatric poison control center in Italy

Total – no. (%)

351

Age (years) - median (IQR, 25° - 75°)

3.0 (8.1, 1.7–9.8)

Sex (females)

203 (57.8)

Male to female ratio

1:1.4

Type of contact

 - Phone call

223 (63.5)

 - Admission to ED

121 (34.5)

 - Both

7 (2.0)

Reason for intake

 - Wrong use

144 (41.0)

 - Accidental intake

132 (37.6)

 - Suicidal intent

74 (21.1)

 - Correct usea

1 (0.3)

Drug taken

 - Paracetamol

230 (65.5)

 - Ibuprofene

119 (33.9)

 - Both

2 (0.6)

More than 1 molecule takenb

21 (6.0)

Symptomatic

26 (7.4)

Comorbidities

69 (19.7)

Type of drug intake

 - Ingestion

309 (88.0)

 - Oral/mucosal

10 (2.8)

 - Injection

1 (0.3)

 - Other

31 (8.8)

Place of intake

 - At home

342 (97.4)

 - At hospital

2 (0.6)

 - Other/unknown

7 (2.0)

Grading of intoxication

 - Mild

275 (78.3)

 - Moderate

66 (18.8)

 - Severe

8 (2.3)

 - NA

2 (0.5)

Likelihood of intoxication

 - Not intoxicated

247 (70.4)

 - Suspected intoxication

40 (11.4)

 - Possible intoxication

25 (7.1)

 - Probable intoxication

15 (4.3)

 - Certain intoxication

13 (3.7)

 - Not indicated

11 (3.1)

Hospitalization

107 (30.5)

 - Pediatric department

62 (57.9)

 - Brief intensive observation

43 (40.2)

 - Pediatric intensive care unit

1 (0.9)

  1. aAgitation in a child after administration of a standard dose of paracetamol
  2. bApart from paracetamol or ibuprofen