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Table 3 Comparison of patients who took paracetamol and ibuprofena

From: Adverse drugs reactions to paracetamol and ibuprofen in children: a 5-year report from a pediatric poison control center in Italy

 

Paracetamol

Ibuprofen

p-value

Total – no. (%)

230

119

 

Age (years) - median (IQR, 25° - 75°)

2.9 (12.1, 1.3–13.3)

3.2 (5.1, 2.2–7.3)

0.191

Sex (females)

138 (60.0)

63 (52.9)

0.206

Male to female ratio

1:1.5

1:1.1

Type of contact

 - Phone call

139 (60.4)

84 (70.6)

0.061

 - Admission to ED

86 (37.4)

33 (27.7)

0.071

 - Both

5 (2.2)

2 (1.7)

1.000

Reason for intake

 - Wrong use

105 (45.7)

39 (32.8)

0.021

 - Accidental intake

67 (29.1)

65 (54.6)

< 0.001

 - Suicidal intent

57 (24.8)

15 (12.6)

0.008

 - Correct use*

1 (0.4)

1.000

More than 1 molecule taken**

14 (6.1)

5 (4.2)

0.462

Symptomatic

19 (8.3)

7 (5.9)

0.422

Comorbidities

51 (22.2)

18 (15.1)

0.117

Type of drug intake

 - Ingestion

189 (82.2)

118 (99.2)

< 0.001

 - Oral/mucosal

10 (4.3)

0.018

 - Injection

1 (0.4)

1.000

 - Other

30 (13.0)

1 (0.8)

< 0.001

Place of intake

 - At home

226 (98.3)

115 (96.6)

0.452

 - At hospital

2 (0.9)

0.549

 - Other/unknown

2 (0.9)

4 (3.4)

0.186

Grading of intoxication

 - Mild

169 (73.5)

106 (89.1)

0.001

 - Moderate

53 (23.0)

11 (9.2)

0.001

 - Severe

7 (3.0)

1 (0.8)

0.273

 - NA

1 (0.4)

1 (0.8)

1.000

Likelihood of intoxication

 - Not intoxicated

155 (67.4)

92 (77.3)

0.053

 - Suspected intoxication

24 (10.4)

14 (11.8)

0.705

 - Possible intoxication

22 (9.6)

3 (2.5)

0.016

 - Probable intoxication

11 (4.8)

3 (3.4)

0.535

 - Certain intoxication

13 (5.7)

0.006

 - Not indicated

5 (2.2)

6 (5.0)

0.195

Hospitalization

 - Pediatric department

47 (60.3)

14 (51.9)

0.446

 - Brief intensive observation

30 (38.5)

13 (48.1)

0.378

 - Pediatric intensive care unit

1 (1.3)

1.000

  1. aTwo cases of both paracetamol and ibuprofen intake were removed