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Table 1 Clinical information of children

From: Clinical Evaluation of Metagenomic Next-Generation Sequencing for the detection of pathogens in BALF in severe community acquired pneumonia

Clinical characteristics

Characteristics

 Sex, male, n (%)

41 (48.8%)

 Age, mean (range), years

4.4 (0.17–14)

Symptoms or signs

 Fever, n (%)

62 (73.8%)

 Cough, n (%)

78 (92.9%)

 Dyspnea, n (%)

30 (35.7%)

 Chest pain, n (%)

10 (11.9%)

 Hemoptysis, n (%)

2 (2.4%)

 Mentally weak/poor, n (%)

23 (27.4%)

 Whoop, n (%)

22 (26.2%)

 Rale, n (%)

65 (77.4%)

 Diminished respiration, n (%)

26 (31.0%)

Imaging features

 Consolidation ≥ 1/2 of the lung, n (%)

28 (33.3%)

 Pulmonary atelectasis, n (%)

20 (23.8%)

 Pleural effusion, n (%)

24 (28.6%)

 Pleurisy, n (%)

36 (42.9%)

 Pulmonary interstitial changes, n (%)

7 (8.3%)

 Lung necrosis, n (%)

11 (13.1%)

Laboratory parameters

 White blood cell counts (109 /L) (mean ± sd)

12.57 ± 6.46

 Lymphocyte [%] (mean ± sd)

13.98 ± 6.30

 Neutrophil [%] (mean ± sd)

77.06 ± 11.96

 C-reactive protein (mg/L) (mean ± sd)

77.13 ± 59.58

 Procalcitonin (ng/mL) (mean ± sd)

11.03 ± 17.57

Basic disease

 Congenital heart disease, n (%)

6 (7.1%)

 Primary ciliary dyskinesia, n (%)

1 (1.2%)

 Asthma, n (%)

4 (4.8%)

 Hepatoblastoma, n (%)

1 (1.2%)

 Renal malformations, n (%)

1 (1.2%)

 Giant gyrus malformation, n (%)

1 (1.2%)

 Diabetes, n (%)

1 (1.2%)

 Chronic granuloma, n (%)

1 (1.2%)

 The pelvic neoplasm, n (%)

1 (1.2%)

 Congenital cleft palate, n (%)

1 (1.2%)

Pre-admission interventions

 

 Antibiotics, n (%)

72. (85.7%)

 Glucocorticoid, n (%)

20 (23.8%)