Table 3 Diagnostic criteria for invasive aspergillosis [10]

Certain

Histological or cytological evaluation of lung tissue with hyphae on needle aspiration or biopsy in which hyphae or melanized yeast-like forms are associated to tissue damage

or

Positive culture test for Aspergillus on pulmonary specimen taken by sterile procedure

and

Clinical or radiologic abnormalities consistent with infection

Probable

At least 1 host factor (tab. 2)

and

Mycological evidence

- positive microscopy or culture for Aspergillus on sputum, BAL bronchial brush, or aspirate

- positive Aspergillus PCR (at least 2 tests)

- positive antigenic assay^a

AND

Clinical criteria consistent with infection^b

Possible

At least 1 host factor (tab.2)

and

Clinical criteria compatible with infection^b