Table 3 Demographic, clinical and biochemical data of two patients with already diagnosed type 1 diabetes admitted to pediatric intensive care unit for severe secondary diabetic ketoacidosis
Patient 1 | Patient 2 | |
|---|---|---|
Age (years) | 13.3 | 6.5 |
Gender | Female | Female |
Height (Z-score) | -0.75 | -1.46 |
Weight (Z-score) | -2.10 | -2.30 |
BMI (Z-score) | -1.96 | -1.94 |
Family history of T1D (1st degree) | No | Unknown |
Low household income | Yes | Yes |
Immigrant background | Yes | Yes |
Clinical presentation | ||
Kussmaul’s breathing | Yes | Yes |
Polyuria and polydipsia | Yes | No |
Gastrointestinal symptoms | Yes | No |
Severe neurological impairment (GCS < 9) | No | Yes |
Moderate neurological impairment (GCS between 9 and 13) | No | No |
Biochemical data | ||
Blood glucose at admission (mg/dl) | 750 | 698 |
Venous pH | 6.80 | 6.83 |
Serum bicarbonate (mmol/L) | 5.6 | 3.0 |
Base excess (mmol/L) | -31 | Unknown |
BUN (mg/dl) | 74 | 109 |
Serum creatinine (mg/dl) | 1.3 | 1.2 |
Serum potassium (mg/dl) | 6.2 | 3.4 |
HbA1c (%) | 8.1 | 7.6 |
DKA treatment | ||
Duration of DKA treatment (hours) | 96 | 48 |
Bicarbonate administration | No | No |
Outcomes | ||
Acute kidney injury | No | Yes |
Cerebral edema | No | Yes |
MOF | No | Yes |
Mortality | No | No |