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Table 2 Demographic, clinical, and laboratory data of the studied groups at admission before treatment

From: Citicoline in hypoxic ischemic encephalopathy in neonates: a randomized controlled trial

Parameters

Citicoline group

Control group

P

GA (weeks)

38.3 ± 1.8

38.1 ± 1.7

0.658

Birth Weight (gm)

2990 ± 670

2850 ± 590

0.331

Sex (male:female)

20:20

27:13

0.112

Duration of resuscitation (min)

11 (6–20)

9 (5–19)

0.068

Apgare score at 10 min

3.58 ± 1.26

3.60 ± 1.32

0.889

PH (first hour)

6.98 ± 0.11

7.01 ± 0.10

0.305

HCO3

12 (2–19)

12.5 (2–20)

0.012

Base deficit

16.13 ± 1.04

16 ± 0.93

0.679

Urinary Lactate/creatine ratio

0.79 ± 0.09

0.80 ± 0.09

0.468

Sarnat staging: N (%)

 -stage 2

19 (47.5%)

23 (57.5%)

0.370

 -stage 3

21 (52.5%)

17(42.5%)

EEG: N (%)

 -Normal continuous

22 (55%)

28 (70%)

0.554

 -Low voltage

5 (12.5%)

2 (5%)

 -Burst suppression

5 (12.5%)

4 (10%)

 -Seizure activity

7 (17.5%)

4 (10%)

 -Paroxysmal generalized epileptiform

1 (2.5%)

2 (5%)

 
  1. GA gestational age, HCO3 bicarbonate, EEG electroencephalogram