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Table 1 Clinical characteristics & KT related data of included KTRs (n = 83)

From: Multidrug resistant 1 (MDR1) C3435T and G2677T gene polymorphism: impact on the risk of acute rejection in pediatric kidney transplant recipients

Age at transplantation (years)

Mean ± SD

9.3 ± 2.9

Post-transplant follow-up duration (months)

median (IQR)

60 (36–93)

Original kidney disease

CAKUT

N (%)

42 (50.6%)

NONE CAKUT

N (%)

41 (49.4%)

Family history of any kidney disease

N (%)

6 (7.2%)

Patients required hemodialysis before transplantation

N (%)

79 (95.2%)

Pre-epmptive kidney transplantation

N (%)

4 (4.8%)

Hemodialysis duration (months)

median (IQR)

12 (1–60)

Native nephrectomy

No

N (%)

43 (51.8%)

Unilateral

N (%)

12 (14.5%)

Bilateral

N (%)

28 (33.7%)

Cause of nephrectomy

Heavy proteinuria

N (%)

17 (42.5%)

Large polycystic kidney

N (%)

2 (5%)

Pyelonephritic kidney

N (%)

6 (15%)

Marked hydronephrosis

N (%)

15 (37.5%)

Anthropometric measures at enrollment in the study

Weight (Kg)

Mean ± SD

37 ± 11.9

Height (m)

Mean ± SD

1.36 ± 0.17

BMI (kg/m2)

Mean ± SD

19.4 ± 4.5

*CMV risk stratification

Low risk

N (%)

8 (9.6%)

Intermediate

N (%)

70 (84.3%)

High risk

N (%)

5 (6%)

Donor/recipient HLA mismatch

4/6

N (%)

3 (3.6%)

3/6

N (%)

50 (60.2%)

2/6

N (%)

25 (30.1%)

1/6

N (%)

3 (3.6%)

0/6

N (%)

2 (2.4%)

Antibody induction therapy

Basiliximab

N (%)

43 (51.8%)

ATG

N (%)

40 (48.2%)

Preemptive PEX

N (%)

15 (18.1%)

Maintenance IS other than TAC

MMF

N (%)

82 (98.8%)

Azathioprine

N (%)

1 (1.2%)

  1. KT; kidney transplantation, KTR ; kidney transplant recipients, N; number, SD; standard deviation, IQR; interquartile range, CAKUT; congenital anomalies of kidney and urinary tract, Kg; kilograms, m; meter, BMI; body mass index, CMV; cytomegalo virus, HLA; human leukocytic antigen, ATG: anti thymocyte globulin, PEX; plasma exchange, IS; immunosuppressive, TAC; tacrolimus, MMF; mycophenolic mofetil.* CMV IgG: Low risk (D -, R -), intermediate risk either (D+, R+) or (D-, R+), high risk (D+, R-)