Articles

Immunization against A/H1N1 pandemic flu (2009–2010) in pediatric patients at risk. What might be the most effective strategy? The experience of an health district of Northern Italy

Vaccination coverage rates against pandemic flu were far below those required by Italian Public Health Authorities.

Authors: Giuseppe Gregori, Fabio Faccini, Ermanno Bongiorni, Ilario Maffini and Roberto Sacchetti

An unusual case of foreign body aspiration mimicking cavitary tuberculosis in adolescent patient: Thread aspiration

Foreign body aspiration continues to be a serious problem in childhood and adolescent period with significant rate of morbidity and rarely mortality. Half of the foreign body aspiration cases have no history o...

Authors: Erkan Cakir, Emel Torun, Zeynep Seda Uyan, Ozge Akca and Omer Soysal

Severe reaction in a child with asymptomatic codfish allergy: Food challenge reactivating recurrent pancreatitis

An 8-year-old child during the first year of life manifested severe atopic dermatitis and chronic diarrhea with mucorrhea and rectal bleeding; a fish-free diet was started based on weakly positive skin-prick t...

Authors: Katia Pellegrino, Leila Emma D’Urbano, Maria Cristina Artesani, Carla Riccardi, Sandro Mancini, Sergio Bella, Federico Alghisi and Giovanni Cavagni

High gamma activity of 60–70 Hz in the area surrounding a cortical tuber in an infant with tuberous sclerosis

To detect the epileptogenic region causing epileptic spasms in an infant with tuberous sclerosis (TS).

Authors: Kaori Irahara, Eiji Nakagawa, Ryoko Honda, Kenji Sugai, Masayuki Sasaki, Takanobu Kaido, Yu Kaneko, Akio Takahashi and Taisuke Otsuki

Sensory integration and activities of daily living in children with developmental coordination disorder

The aim of our study was to evaluate sensory integration and activities of daily living in children with developmental coordination disorder

Authors: Bülent Elbasan, Hlya Kayıhan and Irem Duzgun

Posttraumatic stress symptoms in children diagnosed with type 1 diabetes

Studies consistently found remarkable rates of posttraumatic stress symptoms (PTSS) in children with chronic diseases. But, only one study had searched PTSS in children with diabetes, until now. So, the presen...

Authors: Şahika G Şişmanlar, Emine Demirbaş-Çakir, Işık Karakaya, Filiz Çizmecioğlu, Cavit I Yavuz, Şükrü Hatun and Belma Ağaoğlu

Chest wall TB and low 25-hidroxy-vitamin D levels in a 15-month-old girl

Parietal chest wall tuberculosis is an extremely rare manifestation of tuberculosis (TB) in children. We present the case of a 15 month-old girl presenting with a chest wall lesion initially thought to be of n...

Authors: Danilo Buonsenso, Benedetta Focarelli, Maria Scalzone, Antonio Chiaretti, Claudia Gioè, Manuela Ceccarelli and Piero Valentini

Inflammation and neurological adverse drugs reactions: a case of long lasting impaired consciousness after oxatomide administration in a patient with gastroenteritis

Oxatomide at therapeutic doses generates occasionally drowsiness in children. When administered at toxic doses, however oxatomide may induce long lasting impaired consciousness. We now report a case of severe ...

Authors: Stefania Antoniazzi, Dario Cattaneo, Valentina Perrone, Carla Carnovale, Simonetta Cherubini, Maria Carmela Mugolino, Francesco Clementi, Gianvincenzo Zuccotti, Emilio Clementi and Sonia Radice

Celiac disease in type 1 diabetes mellitus

Celiac Disease (CD) occurs in patients with Type 1 Diabetes (T1D) ranging the prevalence of 4.4-11.1% versus 0.5% of the general population. The mechanism of association of these two diseases involves a shared...

Authors: Maria Erminia Camarca, Enza Mozzillo, Rosa Nugnes, Eugenio Zito, Mariateresa Falco, Valentina Fattorusso, Sara Mobilia, Pietro Buono, Giuliana Valerio, Riccardo Troncone and Adriana Franzese

Multiple endocrine neoplasias type 2B and RET proto-oncogene

Multiple Endocrine Neoplasia type 2B (MEN 2B) is an autosomal dominant complex oncologic neurocristopathy including medullary thyroid carcinoma, pheochromocytoma, gastrointestinal disorders, marphanoid face, a...

Authors: Giuseppe Martucciello, Margherita Lerone, Lara Bricco, Gian Paolo Tonini, Laura Lombardi, Carmine G Del Rossi and Sergio Bernasconi

Novel mutatıons and diverse clinical phenotypes in recombınase-activating gene 1 deficiency

Severe combined immunodeficiency is within a heterogeneous group of inherited defects throughout the development of T- and/or B-lymphocytes. Mutations in recombinase-activating genes 1 or 2 (RAG1/2) represent ...

Authors: Necil Kutukculer, Nesrin Gulez, Neslihan Edeer Karaca, Guzide Aksu and Afig Berdeli

Mandibular distraction in neonates: indications, technique, results

The Pierre Robin Sequence features were first described by Robin in 1923 and include micrognathia, glossoptosis and respiratory distress with an incidence estimated as 1:8,500 to 1:20,000 newborns. Upper airwa...

Authors: Enrico Sesenna, Alice S Magri, Cinzia Magnani, Bruno C Brevi and Marilena L Anghinoni

Development and validation of serum bilirubin nomogram to predict the absence of risk for severe hyperbilirubinaemia before discharge: a prospective, multicenter study

Early discharge of healthy late preterm and full term newborn infants has become common practice because of the current social and economic necessities. Severe jaundice, and even kernicterus, has developed in ...

Authors: Costantino Romagnoli, Eloisa Tiberi, Giovanni Barone, Mario De Curtis, Daniela Regoli, Piermichele Paolillo, Simonetta Picone, Stefano Anania, Maurizio Finocchi, Valentina Cardiello, Lucia Giordano, Valentina Paolucci and Enrico Zecca

De-hospitalization of the pediatric day surgery by means of a freestanding surgery center: pilot study in the lazio region

Day surgery should take place in appropriate organizational settings. In the presence of high volumes, the organizational models of the Lazio Region are represented by either Day Surgery Units within continuou...

Authors: Giovanni Mangia, Franco Bianco, Alma Ciaschi, Elisabetta Di Caro, Eufrasia Frattarelli and Giacinto Antonio Marrocco

Obesity in patients with acute lymphoblastic leukemia in childhood

Acute lymphoblastic leukemia is the most common malignancy in childhood. Continuous progress in risk-adapted treatment for childhood acute lymphoblastic leukemia has secured 5-year event-free survival rates of...

Authors: Lorenzo Iughetti, Patrizia Bruzzi, Barbara Predieri and Paolo Paolucci

Abilities of preschoolers: comparing different tools

There is a strong need for studies evaluating tests in terms both of psychometric properties (i.e. their efficacy or ability to be helpful in reaching a diagnosis) and of their cost-effectiveness (i.e. their e...

Authors: Matteo Chiappedi, Erika Maffioletti, Fausta Piazza, Nicole D'Adda, Marta Tamburini and Umberto Balottin

Effects of chest physiotherapy and aerobic exercise training on physical fitness in young children with cystic fibrosis

Cystic fibrosis is a multisystem disease where the main problems are existing in the respiratory system. Aerobic exercise programs are effective in increasing physical fitness and muscle endurance in addition ...

Authors: Bulent Elbasan, Nur Tunali, Irem Duzgun and Ugur Ozcelik

About the need to use specific population references in estimating paediatric hypertension: Sardinian blood pressure standards (age 11-14 years)

Previous Italian paediatric blood pressure (BP) tables overestimated the prevalence of hypertension in adolescents of specific geographic areas, such as Sardinia, an island in the Mediterranean Sea. This is pr...

Authors: Pier Paolo Bassareo, Andrea Raffaele Marras and Giuseppe Mercuro

Zinc, ferritin, magnesium and copper in a group of Egyptian children with attention deficit hyperactivity disorder

Attention deficit hyperactivity disorder is a behavioral syndrome of childhood characterized by inattention, hyperactivity and impulsivity. There were many etiological theories showed dysfunction of some brain...

Authors: Magdy M Mahmoud, Abdel-Azeem M El-Mazary, Reham M Maher and Manal M Saber

Quality of life measures in Italian children with atopic dermatitis and their families

The impact of atopic dermatitis (AD) on children's quality of life (QoL) in US and European countries is relatively well known, though rarely evaluated in the Italian population. Moreover, the association betw...

Authors: Fiorella Monti, Francesca Agostini, Francesca Gobbi, Erica Neri, Sandra Schianchi and Fabio Arcangeli

"Electro-clinical syndromes" with onset in paediatric age: the highlights of the clinical-EEG, genetic and therapeutic advances

The genetic causes underlying epilepsy remain largely unknown, and the impact of available genetic data on the nosology of epilepsy is still limited. Thus, at present, classification of epileptic disorders sho...

Authors: Pasquale Parisi, Alberto Verrotti, Maria Chiara Paolino, Rosa Castaldo, Filomena Ianniello, Alessandro Ferretti, Francesco Chiarelli and Maria Pia Villa

Pediatric febrile urinary tract infections: the current state of play

Studies undertaken in recent years have improved our understanding regarding the consequences and management of febrile urinary tract infections (UTIs), which are amongst the most common serious bacterial infe...

Authors: Ian K Hewitt and Giovanni Montini

Symptomatic and asymptomatic candidiasis in a pediatric intensive care unit

This study aimed to examine the incidence, epidemiology, and clinical characteristics of symptomatic and asymptomatic candidiasis in a pediatric intensive care unit (PICU), and to determine the risk factors as...

Authors: Ali Ertug Arslankoylu, Necdet Kuyucu, Berna Seker Yilmaz and Semra Erdogan

Meconium obstruction in absence of cystic fibrosis in low birth weight infants: an emerging challenge from increasing survival

Meconium abnormalities are characterized by a wide spectrum of severity, from the meconium plug syndrome to the complicated meconium ileus associated with cystic fibrosis. Meconium Related Ileus in absence of ...

Authors: Valentina Filomena Paradiso, Vito Briganti, Lucia Oriolo, Riccardo Coletta and Alessandro Calisti

Low adherence to influenza vaccination campaigns: is the H1N1 virus pandemic to be blamed?

Over the last few months, debates about the handling of the influenza virus A (H1N1) pandemic took place, in particular regarding the change of the WHO pandemic definition, economic interests, the dramatic com...

Authors: Valeria Trivellin, Vera Gandini and Luigi Nespoli

DRACMA one year after: Which changes have occurred in diagnosis and treatment of CMA in Italy?

Authors: Alessandro Fiocchi, Holger Schunemann, Luigi Terracciano, Marco Albarini, Alberto Martelli, Massimo Landi, Enrico Compalati and Giorgio Walter Canonica

End point prick test: could this new test be used to predict the outcome of oral food challenge in children with cow's milk allergy?

Cow's milk allergy (CMA) is the most frequent food allergy in childhood; the trend of CMA is often characterized by a progressive improvement to achieve tolerance in the first 4 to 5 years of life.

Authors: Federica Bellini, Giampaolo Ricci, Arianna Dondi, Valentina Piccinno, Federico Angelini and Andrea Pession

Gaslini's tracheal team: preliminary experience after one year of paediatric airway reconstructive surgery

congenital and acquired airway anomalies represent a relatively common albeit challenging problem in a national tertiary care hospital. In the past, most of these patients were sent to foreign Centres because ...

Authors: Michele Torre, Marcello Carlucci, Stefano Avanzini, Vincenzo Jasonni, Philippe Monnier, Vincenzo Tarantino, Roberto D'Agostino, Renato Vallarino, Mirta Della Rocca, Andrea Moscatelli, Anna Dehò, Lucio Zannini, Nicola Stagnaro, Oliviero Sacco, Serena Panigada and Pietro Tuo

Castleman's disease in childhood: report of three cases and review of the literature

Castleman's disease (CD) is a rare, localized or generalized, lymphoproliferative disorder with a frequent mediastinal location, but possible in any lymph node or extra nodal site. It usually appears in young ...

Authors: Piero Farruggia, Antonino Trizzino, Nunzia Scibetta, Giovanni Cecchetto, Patrizia Guerrieri, Emanuele SG D'Amore and Paolo D'Angelo

Immune-related disorders in families of children with inflammatory bowel disease - A prospective cohort study

The aim of this paper was to examine the prevalence of immune-related disorders in families of children with inflammatory bowel disease (IBD) compared to those without IBD.

Authors: Alyzée M Sibtain, Donald Spady and Wael El-Matary

A randomized, double-blind, placebo-controlled trial of paracetamol and ketoprofren lysine salt for pain control in children with pharyngotonsillitis cared by family pediatricians

To evaluate the analgesic effect and tolerability of paracetamol syrup compared to placebo and ketoprofen lysine salt in children with pharyngotonsillitis cared by family pediatricians.

Authors: Nicolino Ruperto, Luigi Carozzino, Roberto Jamone, Federico Freschi, Gianfranco Picollo, Marcella Zera, Ornella Della Casa Alberighi, Enrica Salvatori, Alessandra Del Vecchio, Paolo Dionisio and Alberto Martini

Inhaled Surfactant in the treatment of accidental Talc Powder inhalation: a new case report

The use of talcum powder is incorrectly part of the traditional care of infants. Its acute aspiration is a very dangerous condition in childhood. Although the use of baby powder has been discouraged from many ...

Authors: Federico Matina, Mirella Collura, Maria Cristina Maggio, Patrizio Vitulo, Caterina Lo Piparo and Giovanni Corsello

New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future

Leukaemia immunotherapy represents a fascinating and promising field of translational research, particularly as an integrative approach of bone marrow transplantation. Adoptive immunotherapy by the use of dono...

Authors: Ettore Biagi, Virna Marin, Greta Maria Paola Giordano Attianese, Irene Pizzitola, Sarah Tettamanti, Elisabetta Cribioli and Andrea Biondi

Asymptomatic bacteriuria in children with sickle cell anemia at The University of Nigeria teaching hospital, Enugu, South East, Nigeria

Urinary tract infection (UTI) is a common cause of childhood morbidity and mortality in the tropics. Children with sickle cell anemia (SCA) may have compromised kidney function arising from repeated vaso-occlu...

Authors: Bartholomew F Chukwu, Henrietta U Okafor and Anthony N Ikefuna

Foreign children with cancer in Italy

There has been a noticeable annual increase in the number of children coming to Italy for medical treatment, just like it has happened in the rest of the European Union. In Italy, the assistance to children su...

Authors: Roberto Rondelli, Giorgio Dini, Marisa De Rosa, Paola Quarello, Gianni Bisogno, Maurizio Aricò, Carivaldo Vasconcelos, Paolo Tamaro, Gabriella Casazza, Marco Zecca, Clementina De Laurentis, Fulvio Porta and Andrea Pession

Respiratory tract infection is the major cause of the ambulatory visits in children

As children represent the future, ensuring that they receive proper health care should be a primary concern of our societies. Epidemiological research underpins the importance of effective child health care st...

Authors: PeiFen Liao, MinSho Ku, KoHuang Lue and HaiLun Sun

Prolonged survival after splenectomy in Wiskott-Aldrich syndrome: a case report

Wiskott-Aldrich syndrome is a rare X-linked immunodeficiency disorder that is characterized by a variable clinical phenotype. Matched donor bone marrow transplantation is currently the only curative therapeuti...

Authors: Kostas N Syrigos, Nektaria Makrilia, Jeffrey Neidhart, Michael Moutsos, Sotirios Tsimpoukis, Maria Kiagia and Muhammad W Saif

Intrauterine growth retardation - small events, big consequences

Intrauterine growth retardation refers to a rate of growth of a fetus that is less than normal for the growth potential of a fetus (for that particular gestational age). As one of the leading causes of perinat...

Authors: Taimur Saleem, Nida Sajjad, Sanna Fatima, Nida Habib, Syed R Ali and Maqbool Qadir

Antibiotic prescribing pattern in paediatric in patients with first time wheezing

Acute wheezers for the first time in life are an important target group for efforts aimed at reducing unnecessary antibiotic use.

Authors: Soumya Patra, Varinder Singh, Harish K Pemde and Jagdish Chandra

Short term efficacy of nebulized beclomethasone in mild-to-moderate wheezing episodes in pre-school children

Few data are available on the usefulness of short term treatment with low-medium dose of inhaled corticosteroids (ICS) in pre-school children with wheezing exacerbations.

Authors: Alberto Papi, Gabriele Nicolini, Attilio L Boner, Eugenio Baraldi, Renato Cutrera, Leonardo M Fabbri and Giovanni A Rossi

Obesity and craniopharyngioma

An epidemic of pediatric obesity has occurred across the world in recent years. There are subgroups within the population at high-risk of becoming obese and especially of having experience of precocious cardio...

Authors: Lorenzo Iughetti and Patrizia Bruzzi

Urinary hepcidin level as an early predictor of iron deficiency in children: A case control study

The ideal screening test would be capable of identifying iron deficiency in the absence of anemia. We tried to detect role of urinary hepcidin-25 level in early prediction of iron deficiency in children.

Authors: Mohammed Sanad and Amal F Gharib

The use of ultrasound in clinical setting for children affected by NAFLD: is it safe and accurate?

Non-alcoholic fatty liver disease (NAFLD) has become over the last decade the most common form of chronic liver disease in children and adults. Thus, establishing the diagnosis of NAFLD is of utmost importance...

Authors: Valerio Nobili, Claudia Della Corte, Lidia Monti, Anna Alisi and Ariel Feldstein

Acute appendicitis in preschoolers: a study of two different populations of children

To assess the incidence and the risk factors implicated in acute appendicitis in preschoolers in our region.

Authors: Stefanos Gardikis, Alexandra Giatromanolaki, Katerina Kambouri, Gregorios Tripsianis, Efthimios Sivridis and George Vaos

Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study

Recently, hepcidin expression in adipose tissue has been described and shown to be increased in patients with severe obesity. We tried to assess the effect of obesity on hepcidin serum levels and treatment out...

Authors: Mohammed Sanad, Mohammed Osman and Amal Gharib

An overview of motor skill performance and balance in hearing impaired children

Childhood hearing impairment is a common chronic condition that may have a major impact on acquisition of speech, social and physical development. Numerous literature states that injury to the vestibular organ...

Authors: Venkadesan Rajendran and Finita Glory Roy

Bacterial isolates of early-onset neonatal sepsis and their antibiotic susceptibility pattern between 1998 and 2004: an audit from a center in India

Epidemiology and surveillance of neonatal sepsis helps in implementation of rational empirical antibiotic strategy.

Authors: Ramesh Bhat Y, Leslie Edward S Lewis and Vandana KE

Parent satisfaction with a pediatric practice in Germany: A questionnaire-based study

Parental satisfaction with a pediatric day center is essential for the medical treatment of children, since it is closely related to compliance. In order to ascertain factors which predict parental satisfactio...

Authors: Anne Weissenstein, Alexandra Straeter, Gloria Villalon, Elisabeth Luchter and Stefan Bittmann

Blood pressure to height ratios as simple, sensitive and specific diagnostic tools for adolescent (pre)hypertension in Nigeria

The age-, gender-, and height-percentile requirements of the 'gold-standard' for the diagnosis of (pre)hypertension in adolescents make it time-consuming for clinicians and difficult-to-use by non-professional...

Authors: Chukwunonso ECC Ejike

Prevalence and clinical pattern of paediatric HIV infection at the University College Hospital, Ibadan, Nigeria: a prospective cross-sectional study

The prevalence of Paediatric HIV infection is largely unknown in many countries in sub-Saharan Africa. This study was aimed at determining the prevalence, clinical pattern of HIV infection and outcome among ne...

Authors: Babatunde O Ogunbosi, Regina E Oladokun, Biobele J Brown and Kikelomo I Osinusi