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  1. Aplasia cutis congenita (ACC), classified in nine groups, is likely to be underreported, since milder isolated lesions in wellbeing newborns could often be undetected, and solitary lesions in the context of po...

    Authors: Ingrid Anne Mandy Schierz, Mario Giuffrè, Antonello Del Vecchio, Vincenzo Antona, Giovanni Corsello and Ettore Piro

    Citation: Italian Journal of Pediatrics 2020 46:25

    Content type: Research

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  2. Patients affected by acute central nervous system (ACNS) infectionsmay present different complications, including neuropsychological disorders. Nevertheless, psychopathological impairment has been rarely measu...

    Authors: Elena Bozzola, Giulia Spina, Paola Bergonzini, Mauro Bozzola, Massimiliano Raponi and Alberto Villani

    Citation: Italian Journal of Pediatrics 2020 46:23

    Content type: Research

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  3. The optimal management of PDA in very low birth weight (VLBW) infants is still controversial. Aim of our study was to investigate the management of PDA in the Italian neonatal intensive care units (NICU).

    Authors: Benjamim Ficial, Iuri Corsini, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori and Marilena Savoia

    Citation: Italian Journal of Pediatrics 2020 46:22

    Content type: Research

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  4. Neonatal acidaemia at birth can increase neonatal morbidity and mortality and it is predictive of neonatal asphyxia. The umbilical blood gas analysis is a valid tool for the evaluation of neonatal acidaemia. H...

    Authors: Giuseppe De Bernardo, Rita De Santis, Maurizio Giordano, Desiree Sordino, Giuseppe Buonocore and Serafina Perrone

    Citation: Italian Journal of Pediatrics 2020 46:20

    Content type: Research

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  5. The pathophysiological etiologies related with the development of Autism Spectrum Disorders (ASD) remain controversial. Different authors have studied neurotoxins such as mercury (Hg) and their relationship wi...

    Authors: Fernando Gil-Hernández, Antonio R. Gómez-Fernández, María Josede la Torre-Aguilar, Juan L. Pérez-Navero, Katherine Flores-Rojas, Pilar Martín-Borreguero and Mercedes Gil-Campos

    Citation: Italian Journal of Pediatrics 2020 46:19

    Content type: Research

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  6. The upper airways (UA) should be considered as a functional unit. Current functional anatomy divides URT in three, mutually dependent, “junction boxes”: i) the ostio-meatal complex (OMC), ii) the spheno-ethmoi...

    Authors: Attilio Varricchio, Ignazio La Mantia, Francesco Paolo Brunese and Giorgio Ciprandi

    Citation: Italian Journal of Pediatrics 2020 46:18

    Content type: Commentary

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  7. The risk factors for multi-drug resistant infection (MDRI) in the pediatric intensive care unit (PICU) remain unclear. It’s necessary to evaluate the epidemiological characteristics and risk factors for MDRI i...

    Authors: Zaihua Wang and Zhongfang Xia

    Citation: Italian Journal of Pediatrics 2020 46:17

    Content type: Research

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  8. Initial establishment of the human gut microbiota is generally believed to occur immediately following birth, involving key gut commensals such as bifidobacteria that are acquired from the mother. The subseque...

    Authors: Francesca Turroni, Christian Milani, Sabrina Duranti, Gabriele Andrea Lugli, Sergio Bernasconi, Abelardo Margolles, Francesco Di Pierro, Douwe van Sinderen and Marco Ventura

    Citation: Italian Journal of Pediatrics 2020 46:16

    Content type: Review

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  9. We report a case of a 4-year-old girl with acute dacryocystitis complicated with giant lacrimal abscess who underwent open dacryocystectomy as resolutive surgery.

    Authors: Maria Di Cicco, Elisabetta Maria Bellino, Andrea Marabotti, Laura Luti, Diego G. Peroni and Giampiero I. Baroncelli

    Citation: Italian Journal of Pediatrics 2020 46:15

    Content type: Case report

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  10. As more and more diagnostic and interventional options are becoming available for use in pediatric patients, techniques of procedural sedation analgesia (PSA) are being administered in considerably growing num...

    Authors: Harald Sauer, Marie Lobenhofer and Hashim Abdul-Khaliq

    Citation: Italian Journal of Pediatrics 2020 46:14

    Content type: Research

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  11. In recent years, medical training has significantly increased the use of simulation for teaching and evaluation. The retraining of medical personnel in Italy is entrusted to the program of Continuous Education...

    Authors: Alice Covelli, Serena Bardelli, Rosa T. Scaramuzzo, Emilio Sigali, Massimiliano Ciantelli, Marta Del Pistoia, Alessia Longo, Selene Tognarelli, Arianna Menciassi and Armando Cuttano

    Citation: Italian Journal of Pediatrics 2020 46:13

    Content type: Research

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  12. Children with chronic respiratory failure and/or sleep disordered breathing due to a broad range of diseases may require long-term ventilation to be managed at home. Advances in the use of long-term non-invasi...

    Authors: Martino Pavone, Elisabetta Verrillo, Alessandro Onofri, Serena Caggiano, Maria Beatrice Chiarini Testa and Renato Cutrera

    Citation: Italian Journal of Pediatrics 2020 46:12

    Content type: Research

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  13. Given the inadequate overall awareness of the main disease features and treatment modalities of pruritus in pediatric patients with atopic dermatitis, a multidisciplinary Italian expert group met with the majo...

    Authors: May El Hachem, Giuseppe Di Mauro, Roberta Rotunno, Simona Giancristoforo, Cristiana De Ranieri, Carla Maria Carlevaris, Maria Carmen Verga and Iride Dello Iacono

    Citation: Italian Journal of Pediatrics 2020 46:11

    Content type: Review

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  14. Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. ...

    Authors: Tariku Laelago, Tadele Yohannes and Gulima Tsige

    Citation: Italian Journal of Pediatrics 2020 46:10

    Content type: Review

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  15. The aims of the study were to determine the effects of electronic exposure on behaviors of preschoolers, which could provide scientific grounds to the control of digital screen time and usage of electronics.

    Authors: Guodong Xie, Qianye Deng, Jing Cao and Qing Chang

    Citation: Italian Journal of Pediatrics 2020 46:9

    Content type: Research

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  16. In Italy live about 8.7% immigrants, which contribute to more than 15% of all deliveries taking place in Italy. We aimed to investigate whether newborns from high migratory pressure countries (HMPC) mothers ha...

    Authors: Mario De Curtis, Leonardo Villani and Arianna Polo

    Citation: Italian Journal of Pediatrics 2020 46:8

    Content type: Letter to the Editor

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  17. The efficacy of dopamine versus epinephrine for pediatric or neonatal septic shock remains controversial. We conduct a meta-analysis to explore the influence of dopamine versus epinephrine on shock reversal fo...

    Authors: Lingling Wen and Liangyin Xu

    Citation: Italian Journal of Pediatrics 2020 46:6

    Content type: Research

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  18. Drug Hypersensitivity Reactions (DHRs) are considered adverse effects of medications that resemble allergy symptoms. The reported positive clinical history of pediatric drug reactions is about 10%, however, af...

    Authors: A. Piccorossi, G. Liccioli, S. Barni, L. Sarti, M. Giovannini, A. Verrotti, E. Novembre and F. Mori

    Citation: Italian Journal of Pediatrics 2020 46:5

    Content type: Research

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  19. The goal of this literature review is to compare current studies regarding the accuracy of different serum markers in differentiating viral from bacterial pneumonia in the pediatric population with what is emp...

    Authors: Jithin Thomas, Aiste Pociute, Rimantas Kevalas, Mantas Malinauskas and Lina Jankauskaite

    Citation: Italian Journal of Pediatrics 2020 46:4

    Content type: Review

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  20. Congenital cytomegalovirus (cCMV) infection is the most frequent non-genetic cause of sensorineural hearing-loss (SNHL) (i.e., hearing loss due to a cochlear and/or auditory nerve damage). It is widely accepte...

    Authors: Fabio Natale, Mario De Curtis, Bianca Bizzarri, Maria Patrizia Orlando, Massimo Ralli, Giuseppina Liuzzi, Barbara Caravale, Francesco Franco, Aurelia Gaeta, Antonella Giancotti, Francesca Yoshie Russo and Rosaria Turchetta

    Citation: Italian Journal of Pediatrics 2020 46:3

    Content type: Research

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  21. Anemia in newborn babies causes asymptomatic to an acute life-threatening event. If untreated, it leads to a delay in brain maturation, tissue hypoxia, and stunted growth. In Sub-Saharan Africa, its burden ran...

    Authors: Tegenaw Tiruneh, Elias Shiferaw and Bamlaku Enawgaw

    Citation: Italian Journal of Pediatrics 2020 46:1

    Content type: Research

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  22. Virtual Reality (VR) as a tool for pain reduction is the research topic of several clinical trial for Randomized Controlled Trials despite its wide use in the daily clinical practice for non- pharmacological r...

    Authors: Anna Maria Iannicelli, Daniele Vito, Concetta Anna Dodaro, Pasquale De Matteo, Rita Nocerino, Angela Sepe and Valeria Raia

    Citation: Italian Journal of Pediatrics 2019 45:171

    Content type: Review

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  23. Radiation therapy represents an important approach in the therapeutic management of children and adolescents with malignant tumors and its application with modern techniques – including Proton Beam Therapy (PB...

    Authors: Angela Sardaro, Roberta Carbonara, Maria Fonte Petruzzelli, Barbara Turi, Marco Moschetta, Arnaldo Scardapane and Amato Antonio Stabile Ianora

    Citation: Italian Journal of Pediatrics 2019 45:170

    Content type: Review

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  24. Inherited retinal dystrophies are major cause of severe progressive vision loss in children. Early recognition and diagnosis are essential for timely visual rehabilitation during the appropriate stages of the ...

    Authors: Agnese Suppiej, Silvia Marino, Maria Eleonora Reffo, Veronica Maritan, Giovanna Vitaliti, Janette Mailo and Raffaele Falsaperla

    Citation: Italian Journal of Pediatrics 2019 45:168

    Content type: Research

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  25. Fetal alcohol spectrum disorder (FASD) refers to a broad spectrum of disabilities, in infants and children, resulting from moderate to excessive prenatal alcohol exposure.

    Authors: R. Onesimo, C. De Rose, A. B. Delogu, A. Battista, C. Leoni, S. Veltri, G. De Rosa and G. Zampino

    Citation: Italian Journal of Pediatrics 2019 45:167

    Content type: Case report

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  26. Premature thelarche (PT) is a benevolent ailment affecting young girls. Multiple factors are reported to correlate with this condition, but the mechanisms responsible for the onset of PT have not yet been full...

    Authors: Yueqin Xu, Yan Li, Shuang Liang and Guimei Li

    Citation: Italian Journal of Pediatrics 2019 45:166

    Content type: Research

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  27. Cardiac arrhythmias are sometimes encountered in patients with hereditary myopathies and muscular dystrophies. Description of arrhythmias in myopathies and muscular dystrophies is very important, because arrhy...

    Authors: Itaru Hayakawa, Yuichi Abe, Hiroshi Ono and Masaya Kubota

    Citation: Italian Journal of Pediatrics 2019 45:165

    Content type: Case report

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  28. Adolescents and students are encountered with a challenge so-called “internet Addiction”. This issue affects both their physical and mental health, as well as their academic, social, and family performance. Th...

    Authors: Batol Gholamian, Hossein Shahnazi and Akbar Hassanzadeh

    Citation: Italian Journal of Pediatrics 2019 45:164

    Content type: Research

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  29. Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia in children. However, its mechanism of pathogenesis is not fully understood, and microRNAs might play a role. This study aimed to explor...

    Authors: Chu Chu, Xiaoli Lei, Yuqin Li, Yali Luo, Ying Ding, Weifang Zhou and Wei Ji

    Citation: Italian Journal of Pediatrics 2019 45:163

    Content type: Research

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  30. Type 1 diabetes (T1D) has been associated with a higher fracture risk due to alterations in bone structure and metabolism. On the other hand, the important role of the RANKL/OPG/RANK signaling axis in bone phy...

    Authors: Paraskevi Karalazou, Dimitrios Ntelios, Fani Chatzopoulou, Aikaterini Fragou, Maria Taousani, Konstantina Mouzaki, Assimina Galli-Tsinopoulou, Sofia Kouidou and Georgios Tzimagiorgis

    Citation: Italian Journal of Pediatrics 2019 45:161

    Content type: Research

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  31. Mutations in Proline-rich Transmembrane Protein 2 (PRRT2) have been primarily associated with individuals presenting with infantile epilepsy, including benign familial infantile epilepsy, benign infantile epileps...

    Authors: Piero Pavone, Giovanni. Corsello, Sung Yoon Cho, Xena Giada Pappalardo, Martino Ruggieri, Simona Domenica Marino, Dong Kyu Jin, Silvia Marino and Raffaele Falsaperla

    Citation: Italian Journal of Pediatrics 2019 45:159

    Content type: Case report

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  32. Complementary feeding from the age of 6 months along with breastfeeding is essential for the health of infants. The effect of educational interventions on preventing the early or late onset of complementary fe...

    Authors: Ziba Rafieyan-Kopaei, Zohreh Fathian-Dastgerdi, Mohammad Javad Tarrahi and Fereshteh Zamani-Alavijeh

    Citation: Italian Journal of Pediatrics 2019 45:158

    Content type: Research

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  33. Dental trauma is a frequent occurrence in children and adolescent and a correct diagnosis and treatment are essential for a favourable long-term prognosis. The present Guidelines aim to formulate evidence-base...

    Authors: Maria Grazia Cagetti, Piero Alessandro Marcoli, Mario Berengo, Piero Cascone, Livio Cordone, Patrizia Defabianis, Osvalda De Giglio, Nicola Esposito, Antonio Federici, Alberto Laino, Alessandra Majorana, Michele Nardone, Vilma Pinchi, Silvia Pizzi, Antonella Polimeni, Maria Grazia Privitera…

    Citation: Italian Journal of Pediatrics 2019 45:157

    Content type: Review

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  34. Current guidelines recommend assessing and relieving pain in all children and in all instances; yet, in clinical practice, management is frequently suboptimal. We investigated the attitude of Italian family pe...

    Authors: Gian Luigi Marseglia, Maria Alessio, Liviana Da Dalt, Maria Giuliano, Angelo Ravelli and Paola Marchisio

    Citation: Italian Journal of Pediatrics 2019 45:156

    Content type: Research

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  35. Pathogenic variants in KIF1A (kinesin family member 1A) gene have been associated with hereditary spastic paraplegia (HSP) type 30 (SPG30), encopassing autosomal dominant and recessive, pure and complicated forms...

    Authors: Carlotta Spagnoli, Susanna Rizzi, Grazia Gabriella Salerno, Daniele Frattini and Carlo Fusco

    Citation: Italian Journal of Pediatrics 2019 45:155

    Content type: Case report

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  36. Improving infant and young child feeding practices is critical to improved nutrition, health, and development of children. Ethiopia adopted the WHO recommendations of child feeding practices and developed the ...

    Authors: Zegeye Abebe, Amare Tariku, Gashaw Andargie Bikes, Molla Mesele Wassie, Kedir Abdela Gonete, Tadesse Awoke, Ejigu Gebeye, Azeb Atnafu Gete, Melkie Edris Yesuf, Yigzaw Kebede, Kassahun Alemu, Abebaw Addis, Esmael Ali Muhammad, Solomon Mekonnen Abebe, Aysheshim Kasahun belew, Melkamu Tamir Hunegnaw…

    Citation: Italian Journal of Pediatrics 2019 45:154

    Content type: Research

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  37. Teenage childbearing among adolescents aged 15 to 19 is a common sexual and reproductive health (SRH) issue among young people, particularly in developing countries. It is associated with higher maternal and n...

    Authors: Getachew Mullu Kassa, Ayodele O. Arowojolu, Akin-Tunde Ademola Odukogbe and Alemayehu Worku Yalew

    Citation: Italian Journal of Pediatrics 2019 45:153

    Content type: Research

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  38. Two hundred seventy-five thousand maternal deaths, 2.7 million neonatal deaths, and 2.6 million stillbirths have been estimated in 2015 worldwide, almost all in low-income countries (LICs). Moreover, more than...

    Authors: Gregorio Serra, Vincenzo Miceli, Salvatore Albano and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:152

    Content type: Research

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  39. Severe asthma has a substantial epidemiological impact on children and biological treatments can be an option to take into account, as they target specific molecules and pathways involved in its pathogenesis. ...

    Authors: Mattia Giovannini, Francesca Mori, Simona Barni, Maurizio de Martino and Elio Novembre

    Citation: Italian Journal of Pediatrics 2019 45:151

    Content type: Review

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  40. Neonatal sepsis is one of the leading causes of neonatal morbidity and mortality. Despite implementing of different preventive interventions, the burden of neonatal sepsis is reporting in different areas of Et...

    Authors: Mulunesh Alemu, Mulatu Ayana, Hailemariam Abiy, Biniam Minuye, Wubet Alebachew and Aklilu Endalamaw

    Citation: Italian Journal of Pediatrics 2019 45:150

    Content type: Research

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  41. The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Faceb...

    Authors: Elena Bozzola, Giulia Spina, Margherita Ruggiero, Davide Vecchio, Cinthia Caruso, Mauro Bozzola, Anna Maria Staiano, Rino Agostiniani, Antonello Del Vecchio, Giuseppe Banderali, Diego Peroni, Alberto Chiara, Luigi Memo, Renato Turra, Giovanni Corsello and Alberto Villani

    Citation: Italian Journal of Pediatrics 2019 45:149

    Content type: Research

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  42. Heterozygous mutations of the ACAN gene have been associated with a broad spectrum of non-lethal skeletal dysplasias, called Aggrecanopathies. We report a case of a child with severe inflammatory elbow involvemen...

    Authors: Angelo Florio, Riccardo Papa, Roberta Caorsi, Alessandro Consolaro, Roberto Gastaldi, Marco Gattorno and Paolo Picco

    Citation: Italian Journal of Pediatrics 2019 45:148

    Content type: Letter to the Editor

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  43. Breastfeeding is one of the most sensitive stages in the development of children, having many benefits for the mother and the child. The present study aimed to determine factors associated with breastfeeding i...

    Authors: Reyhaneh Rafizadeh, Zahra Heidari, Mahmood Karimy, Fereshteh Zamani-Alavijeh and Marzieh Araban

    Citation: Italian Journal of Pediatrics 2019 45:147

    Content type: Research

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