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  1. Childhood epilepsies are a heterogeneous group of conditions differing in diagnostic criteria, management, and outcome. Late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) is a neurodegenerative condit...

    Authors: Elisabetta Amadori, Marcello Scala, Giulia Sofia Cereda, Maria Stella Vari, Francesca Marchese, Veronica Di Pisa, Maria Margherita Mancardi, Thea Giacomini, Laura Siri, Fabiana Vercellino, Domenico Serino, Alessandro Orsini, Alice Bonuccelli, Irene Bagnasco, Amanda Papa, Carlo Minetti…

    Citation: Italian Journal of Pediatrics 2020 46:92

    Content type: Research

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  2. Under nutrition and overweight typically occur during nutritional transition periods in developing countries including Egypt. Short stature and anemia are public health concern due to its strong link with maln...

    Authors: Ali M. El-Shafie, Zeinab A. Kasemy, Zein A. Omar, Safa H. Alkalash, Amal A. Salama, Kerollos S. Mahrous, Shaimaa M. Hewedy, Nessreen M. Kotb, Heba S. Abd El-Hady, Eman S. Eladawy, Mohamed A. Zeid, Manar E. Abd El Hamid, Emad H. Hemeda, Mohamed A. El-shafie, Esraa A. El-Meligy and Wael A. Bahbah

    Citation: Italian Journal of Pediatrics 2020 46:91

    Content type: Research

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  3. Linezolid is a synthetic antibiotic which is active against most Gram-positive bacteria, especially on Staphylococcus aureus. Its administration can be required when the infection is due to staphylococcus strains...

    Authors: Cinzia Auriti, Fiammetta Piersigilli, Iliana Bersani, Sara Cairoli, Paolina Giuseppina Amante, Daniela Longo and Bianca Maria Goffredo

    Citation: Italian Journal of Pediatrics 2020 46:90

    Content type: Case report

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  4. We highlight the main developments that have been published during the first semester of the last year in the Italian Journal of Pediatrics. We have carefully chosen information from numerous exciting progress...

    Authors: Carlo Caffarelli, Francesca Santamaria, Virginia Mirra, Ermanno Bacchini, Angelica Santoro, Sergio Bernasconi and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2020 46:89

    Content type: Review

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  5. Cerebral palsy (CP) is a non-progressive disorder of movement and posture due to a static insult to the brain. In CP, the depth of investigation is guided by the patients’ medical history and their clinical ex...

    Authors: Liqin Hu, Xiaoqin Xin, Shaobin Lin, Min Luo, Junkun Chen, Hongsheng Qiu, Li Ma and Jungao Huang

    Citation: Italian Journal of Pediatrics 2020 46:88

    Content type: Case report

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  6. Since the outbreak of COVID-19 pandemic, the number of cases registered worldwide has risen to over 3 million. While COVID-19 per se does not seem to represent a significant threat to the pediatric population,...

    Authors: Benedetta Ciacchini, Francesco Tonioli, Cinzia Marciano, Maria Grazia Faticato, Elena Borali, Alessio Pini Prato and Enrico Felici

    Citation: Italian Journal of Pediatrics 2020 46:87

    Content type: Letter to the Editor

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  7. Furosemide is approved in full term neonates to treat edema associated with congestive heart failure, cirrhosis and renal diseases. It is often administered off-label in premature neonates, to treat respirator...

    Authors: Valeria Anna Manfredini, Chiara Cerini, Antonio Clavenna, Andrea Dotta, Maria Letizia Caccamo, Alex Staffler, Luca Massenzi and Rossano Massimo Rezzonico

    Citation: Italian Journal of Pediatrics 2020 46:86

    Content type: Research

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  8. Disruptive behavior can have lifetime consequences for youth. Prevention, early identification and treatment of disruptive behavior can improve outcomes for these youth. The purpose of the present study was to...

    Authors: Marzieh Araban, Ali Montazeri, L. A. R. Stein, Mahmood Karimy and Ali Asghar Haeri Mehrizi

    Citation: Italian Journal of Pediatrics 2020 46:85

    Content type: Research

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  9. The COVID-19 pandemic has surprised the entire population. The world has had to face an unprecedented pandemic. Only, Spanish flu had similar disastrous consequences. As a result, drastic measures (lockdown) h...

    Authors: Fabio Cardinale, Giorgio Ciprandi, Salvatore Barberi, Roberto Bernardini, Carlo Caffarelli, Mauro Calvani, Giovanni Cavagni, Elena Galli, Domenico Minasi, Michele Miraglia del Giudice, Viviana Moschese, Elio Novembre, Francesco Paravati, Diego G. Peroni, Maria Angela Tosca, Giovanni Traina…

    Citation: Italian Journal of Pediatrics 2020 46:84

    Content type: Review

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  10. Data about acute poisoning in Italian pediatric patients are obsolete or absent. This study would partially fill this exiting gap and compare the scene with others around the world.

    Authors: Giovanni N. Berta, Federica Di Scipio, Francesca M. Bosetti, Barbara Mognetti, Federica Romano, Maria E. Carere, Anna C. Del Giudice, Emanuele Castagno, Claudia Bondone and Antonio F. Urbino

    Citation: Italian Journal of Pediatrics 2020 46:83

    Content type: Research

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  11. In internationally adopted children disorders of linear growth, puberty development, thyroid function, and bone metabolism are frequently reported. It is important that these children receive careful auxologic...

    Authors: Stefano Stagi, Valeria Papacciuoli, Djibril Boiro, Chiara Maggioli, Niane Ndeye Ndambao, Stefania Losi, Elena Chiappini, Sonia Toni and Ousmane Ndiaye

    Citation: Italian Journal of Pediatrics 2020 46:82

    Content type: Review

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  12. Hereditary multiple osteochondromas (HMO) is a genetic condition characterized by the presence of multiple osteochondromas, usually at the lateral side of the most active growth plate of a long bone. These les...

    Authors: Andrea Trombetta, Vanessa Migliarino, Flavio Faletra, Egidio Barbi and Gianluca Tornese

    Citation: Italian Journal of Pediatrics 2020 46:81

    Content type: Case report

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  13. An epidemiological transition is interesting Sub-Saharan Africa increasing the burden of non-communicable diseases most of which are of surgical interest. Local resources are far from meeting needs and, consid...

    Authors: Pierluigi Lelli Chiesa, Osman T. M. Osman, Antonio Aloi, Mariagrazia Andriani, Alberto Benigni, Claudio Catucci, Paolo Giambelli, Gabriele Lisi, Faisal M. Nugud, Paola Presutti, Viviana Prussiani, Vincenzo Racalbuto, Fabio Rossi, Giuliana Santoponte, Bruno Turchetta, Diaa Eldinn Yaseen Mohammed Salman…

    Citation: Italian Journal of Pediatrics 2020 46:80

    Content type: Research

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  14. The epidemic of coronavirus disease 2019 (COVID-19) broke out in Wuhan, China, in December 2019 and rapidly spread across the world. In order to counter this epidemic, several countries put in place different ...

    Authors: Maria Pia Fantini, Chiara Reno, Giovanni Battista Biserni, Elena Savoia and Marcello Lanari

    Citation: Italian Journal of Pediatrics 2020 46:79

    Content type: Letter to the Editor

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  15. Clubfoot is the most frequent congenital malformation of the foot, affecting more than 1–2 subjects per 1.000 newborns. Without appropriate treatment, a child with congenital clubfoot will never be able to wal...

    Authors: Daniela Dibello, Valentina Di Carlo, Giulia Colin, Egidio Barbi and Anna M. C. Galimberti

    Citation: Italian Journal of Pediatrics 2020 46:78

    Content type: Commentary

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  16. Vitamin A administration may decrease any stage of retinopathy of prematurity (ROP) in preterm infants. To evaluate whether vitamin A oral supplementation could be preventive in ROP incidence and severity in V...

    Authors: Francesca Garofoli, Donatella Barillà, Micol Angelini, Iolanda Mazzucchelli, Annalisa De Silvestri, Rosanna Guagliano, Lidia Decembrino and Chryssoula Tzialla

    Citation: Italian Journal of Pediatrics 2020 46:77

    Content type: Letter to the Editor

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  17. Studies investigating the prevalence of hypertension and its correlation with anthropometric indices among adolescents are still scarce compared to those conducted in adults of greater than 40 years. So far, n...

    Authors: Godfrey Katamba, David Collins Agaba, Richard Migisha, Agnes Namaganda, Rosemary Namayanja and Eleanor Turyakira

    Citation: Italian Journal of Pediatrics 2020 46:76

    Content type: Research

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  18. Varicella may complicate with cerebellitis in previously healthy children, requiring hospitalization. Aim of our study was to define whether children who experienced varicella cerebellitis have a normal immune...

    Authors: Elena Bozzola, Rita Carsetti, Eva Piano Mortari, Marco Masci, Giulia Spina and Alberto Villani

    Citation: Italian Journal of Pediatrics 2020 46:75

    Content type: Research

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  19. Schinzel-Giedion syndrome (SGS) is a multiple malformation syndrome mainly characterized by severe intellectual disability, distinctive facial features, and multiple congenital anomalies, including skeletal ab...

    Authors: Maria Pia Leone, Pietro Palumbo, Orazio Palumbo, Ester Di Muro, Massimiliano Chetta, Nicola Laforgia, Nicoletta Resta, Alessandro Stella, Stefano Castellana, Tommaso Mazza, Marco Castori, Massimo Carella and Nenad Bukvic

    Citation: Italian Journal of Pediatrics 2020 46:74

    Content type: Case report

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  20. The rate of twinning continues to increase due to the combined effect of a rise in parental age and increased use of assisted reproductive technology. The risk of congenital anomalies in twins is higher than i...

    Authors: Ettore Piro, Ingrid Anne Mandy Schierz, Gregorio Serra, Giuseppe Puccio, Mario Giuffrè and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2020 46:73

    Content type: Research

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  21. Aim of this retrospective study was to describe clinical characteristics, diagnostic work-up, management and follow-up of newborns with neural tube defects (NTDs), admitted to the Mother and Child Department o...

    Authors: Ettore Piro, Gregorio Serra, Ingrid Anne Mandy Schierz, Mario Giuffrè and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2020 46:72

    Content type: Research

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  22. Delayed umbilical cord clamping is associated with greater haemoglobin concentration and iron storage between 3 and 6 months of life and with less need of blood transfusion and lower incidence of neonatal hypo...

    Authors: Giuseppe De Bernardo, Maurizio Giordano, Rita De Santis, Paola Castelli, Desiree Sordino, Daniele Trevisanuto, Giuseppe Buonocore and Serafina Perrone

    Citation: Italian Journal of Pediatrics 2020 46:71

    Content type: Research

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  23. Human Immunodeficiency Virus (HIV) infection and low birth weight (LBW) continue to be significant public health concerns in many low-income countries including Ethiopia. Yet the effect of maternal HIV infecti...

    Authors: Andualem Zenebe, Betelhem Eshetu and Samson Gebremedhin

    Citation: Italian Journal of Pediatrics 2020 46:70

    Content type: Research

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  25. Effective prevention and control strategies are mandatory to prevent SARS-CoV-2 infection.

    Authors: Elisabetta Bignamini, Salvatore Cazzato, Renato Cutrera, Giuliana Ferrante, Stefania La Grutta, Amelia Licari, Enrico Lombardi, Fabio Midulla, Giorgio Piacentini, Massimo Pifferi, Francesca Santamaria, Giancarlo Tancredi and Attilio Turchetta

    Citation: Italian Journal of Pediatrics 2020 46:68

    Content type: Letter to the Editor

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  26. A prompt diagnosis of HIE remains a challenge clinically. This study aimed to identify potential biomarkers of neonatal hypoxic-ischemic encephalopathy (HIE) via a novel proteomic approach, the isobaric tags f...

    Authors: Yuanyuan Zhu, Yajing Yun, Meifang Jin, Gen Li, Hong Li, Po Miao, Xin Ding, Xing Feng, Lixiao Xu and Bin Sun

    Citation: Italian Journal of Pediatrics 2020 46:67

    Content type: Research

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  27. Colorectal polyps are reported in 6,1% of paediatric colonoscopies and in 12% of those performed for lower gastrointestinal bleeding. Although colonoscopy is widely used in paediatric patients, it requires bow...

    Authors: Giovanni Di Nardo, Francesco Esposito, Chiara Ziparo, Caterina Strisciuglio, Francesca Vassallo, Marco Di Serafino, Maria Pia Villa, Pasquale Parisi, Melania Evangelisti, Claudia Pacchiarotti and Vito Domenico Corleto

    Citation: Italian Journal of Pediatrics 2020 46:66

    Content type: Research

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  28. As the quality and quantity of patient-centered care may be perceived differently by recipients and independent observers, assessment of humanization of pediatric care remains an elusive issue. Herein we aim t...

    Authors: C. Mandato, M. A. Siano, A. G. E. De Anseris, M. Tripodi, G. Massa, R. De Rosa, M. Buffoli, A. Lamanna, P. Siani and P. Vajro

    Citation: Italian Journal of Pediatrics 2020 46:65

    Content type: Research

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  30. Coarctation of the aorta (CoA), presenting with local stenosis of the aorta is involved in many cardiovascular processes. However, there has been little research on the mechanism of coarctation of the aorta.

    Authors: Siyu Ma, Junqiang Zheng, Yang Xu, Zhaocong Yang, Yu Zhu, Xiaoqi Su and Xuming Mo

    Citation: Italian Journal of Pediatrics 2020 46:63

    Content type: Research

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  31. Due to novel coronavirus infection emergency, restricting measures have been imposed in Italy. As well as adults, also children are limited in their daily routine.

    Authors: Alberto Villani, Elena Bozzola, Paolo Siani and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2020 46:62

    Content type: Commentary

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  32. Atrioventricular canal defect (AVCD) represents a quite common congenital heart defect (CHD) accounting for 7.4% of all cardiac malformations. AVCD is a very heterogeneous malformation that can occur as a phen...

    Authors: Flaminia Pugnaloni, Maria Cristina Digilio, Carolina Putotto, Enrica De Luca, Bruno Marino and Paolo Versacci

    Citation: Italian Journal of Pediatrics 2020 46:61

    Content type: Review

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  34. Italian laws allow the protection of a child who is suspected to be a victim of abuse through a procedure that can be put in motion by the attending physician in any Emergency Department (article nr. 403 Civil...

    Authors: Federico Poropat, Arianna Canuto, Giulia Caddeo, Erica Predonzani, Laura Novello, Alessandra Zorzetto, Claudio Germani and Egidio Barbi

    Citation: Italian Journal of Pediatrics 2020 46:59

    Content type: Research

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  35. Jaffe-Campanacci syndrome is characterized by multiple non-ossifying fibromas, café-au-lait macules and giant cell granulomas of the jaw. Even if the association between all these peculiar features and neurofi...

    Authors: Silvia Vannelli, Raffaele Buganza, Federica Runfola, Ilaria Mussinatto, Antonio Andreacchio and Luisa de Sanctis

    Citation: Italian Journal of Pediatrics 2020 46:58

    Content type: Case report

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  36. In Italy, as in many European countries, Pediatric Emergency Medicine is not formally recognized as a pediatric subspecialty, hindering nation-wide adoption of standards of care, especially in the field of pro...

    Authors: Idanna Sforzi, Silvia Bressan, Claudia Saffirio, Salvatore De Masi, Leonardo Bussolin, Liviana Da Dalt, Fabio De Iaco, Itai Shavit, Baruch Krauss and Egidio Barbi

    Citation: Italian Journal of Pediatrics 2020 46:57

    Content type: Research

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  37. Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successivel...

    Authors: Domenico Umberto De Rose, Fiammetta Piersigilli, Maria Paola Ronchetti, Alessandra Santisi, Iliana Bersani, Andrea Dotta, Olivier Danhaive and Cinzia Auriti

    Citation: Italian Journal of Pediatrics 2020 46:56

    Content type: Review

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  38. Beckwith-Wiedemann syndrome (BWS) is a genetic overgrowth disorder with variable clinical features and cancer predisposition. In this study, we aim to characterize the clinical features and molecular defects o...

    Authors: Ruixue Wang, Yongmei Xiao, Dan Li, Hui Hu, Xiaolu Li, Ting Ge, Ronghua Yu, Yizhong Wang and Ting Zhang

    Citation: Italian Journal of Pediatrics 2020 46:55

    Content type: Research

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  39. Although disseminated intravascular coagulation (DIC) is a critical disease, there is few gold standard interventions in neonatal medicine. The aim of this study is to reveal factors affecting neonatal DIC at ...

    Authors: Hayato Go, Hitoshi Ohto, Kenneth E. Nollet, Nozomi Kashiwabara, Kei Ogasawara, Mina Chishiki, Shun Hiruta, Ichiri Sakuma, Yukihiko Kawasaki and Mitsuaki Hosoya

    Citation: Italian Journal of Pediatrics 2020 46:54

    Content type: Research

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  40. An early diagnosis of CHARGE syndrome is challenging, especially for the primary care physicians who often take care of neonates with multiple congenital anomalies. Here we report eight cases of CHARGE syndrom...

    Authors: Maria Francesca Bedeschi, Beatrice Letizia Crippa, Lorenzo Colombo, Martina Buscemi, Cesare Rossi, Roberta Villa, Silvana Gangi, Odoardo Picciolini, Claudia Cinnante, Viola Giulia Carlina Fergnani, Paola Francesca Ajmone, Elisa Scola, Fabio Triulzi and Fabio Mosca

    Citation: Italian Journal of Pediatrics 2020 46:53

    Content type: Research

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  41. Feeding intolerance in premature infants is one of the main causes of their long-term hospitalization in NICUs. Massage therapy is a cost-effective intervention that has a positive impact on the health of infa...

    Authors: Leila Seiiedi-Biarag and Mojgan Mirghafourvand

    Citation: Italian Journal of Pediatrics 2020 46:52

    Content type: Review

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  42. Mayer-Rokitansky-Küster-Hauser (MRKHS) syndrome refers to congenital hypoplasia/aplasia of the uterus, the cervix and the upper 2/3 of the vagina, in females with normal ovaries and fallopian tubes, secondary ...

    Authors: Giuliana Morabito, Alessandro Daidone, Flora Murru, Marianna Iaquinto, Elena Faleschini, Egidio Barbi and Giorgio Cozzi

    Citation: Italian Journal of Pediatrics 2020 46:51

    Content type: Case report

    Published on:

  43. Atopic eczema (AE) is the most common inflammatory skin disease in infancy and its prevalence is rising worldwide. It has a wide social impact on the affected children and their families’ lives. AE can have a ...

    Authors: Mattia Giovannini, Davide Geat, Gabriele Barlocco, Riccardo Pertile, Francesca Mori, Cesare Filippeschi, Elio Novembre, Mario Cristofolini and Ermanno Baldo

    Citation: Italian Journal of Pediatrics 2020 46:50

    Content type: Letter to the Editor

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  44. Ascites can develop as a consequence of a number of diseases in childhood. Despite chronic liver disease is the most common cause, several conditions can lead to ascites also in the absence of liver dysfunctio...

    Authors: Alessandro Rossi, Velia Melone, Rossella Turco, Luigi Camera, Eugenia Bruzzese, Erasmo Miele, Annamaria Staiano, Alfredo Guarino and Andrea Lo Vecchio

    Citation: Italian Journal of Pediatrics 2020 46:49

    Content type: Case report

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  45. Massive gastrointestinal bleeding in children is uncommon. Dieulafoy lesion is an uncommon disease which may lead to massive and repeated upper gastrointestinal hemorrhage. We report two cases of gastric Dieul...

    Authors: Giovanni Di Nardo, Gianluca Esposito, Angela Mauro, Letizia Zenzeri, Gian Paolo Ciccarelli, Andrea Catzola, Alessandro Rossi and Vito Domenico Corleto

    Citation: Italian Journal of Pediatrics 2020 46:48

    Content type: Case report

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  46. Planning optimal fluid and inotrope-vasopressor-inodilator therapy is essential in critically ill children. Pulse index Contour Cardiac Output (PiCCO) monitoring is an invasive, hemodynamic monitor that provid...

    Authors: Nagehan Aslan, Dincer Yildizdas, Ozden Ozgur Horoz, Yasemin Coban, Fadli Demir, Sevcan Erdem and Yasar Sertdemir

    Citation: Italian Journal of Pediatrics 2020 46:47

    Content type: Research

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  47. Exposure to hypothermia is somehow unavoidable when a baby comes to life. This is the reason why any possible effort should be made by every caregiver involved during birth, from labour to transfer into the ma...

    Authors: Daniele Merazzi, Ilia Bresesti, Paolo Tagliabue, Maria Grazia Valsecchi, Paola De Lorenzo and Gianluca Lista

    Citation: Italian Journal of Pediatrics 2020 46:46

    Content type: Research

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  48. Fetal programming during in utero life defines the set point of physiological and metabolic responses that lead into adulthood; events happening in “the first 1,000 days” (from conception to 2-years of age), p...

    Authors: Benedetta Raspini, Debora Porri, Rachele De Giuseppe, Marcello Chieppa, Marina Liso, Rosa Maria Cerbo, Elisa Civardi, Francesca Garofoli, Maria Cristina Monti, Mirco Vacca, Maria De Angelis and Hellas Cena

    Citation: Italian Journal of Pediatrics 2020 46:45

    Content type: Research

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  49. Harlequin Ichthyosis is the most severe variant of congenital autosomal recessive ichthyosis, associated with severe morbidity and potentially lethal in early life. At birth, patients present thick and plaque-...

    Authors: Cinzia Auriti, Roberta Rotunno, Andrea Diociaiuti, Silvia Magni Manzoni, Andrea Uva, Iliana Bersani, Alessandra Santisi, Andrea Dotta and May El Hachem

    Citation: Italian Journal of Pediatrics 2020 46:44

    Content type: Case report

    Published on:

  50. Preterm infants are at risk for structural disruption of brain connectivity due to perinatal complications encountered during the fetal and neonatal periods. This study aimed to investigate the development of ...

    Authors: Jong Ho Cha, Yong-Ho Choi, Jong-Min Lee, Joo Young Lee, Hyun-Kyung Park, Jinsup Kim, Il-Kewon Kim and Hyun Ju Lee

    Citation: Italian Journal of Pediatrics 2020 46:43

    Content type: Research

    Published on:

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