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  1. This study investigates the correlation between coagulation levels and the severity of Mycoplasma pneumoniae pneumonia (MPP) in children. In addition, the study analyses the predictive value of coagulation abnorm...

    Authors: Yong-tao Li, Ju Zhang, Meng-zhu Wang, Yu-Mei Ma, Ke Zhi, Fu-Li Dai and Shu-jun Li
    Citation: Italian Journal of Pediatrics 2023 49:143
  2. The hemodynamic status of newborns with intracranial arteriovenous shunts (AVSs) may be extremely complex. Mini-invasive hemodynamic monitoring through innovative techniques such as Near-Infrared Spectroscopy ...

    Authors: Francesca Landolfo, Paola Giliberti, Domenico Umberto De Rose, Flaminia Pugnaloni, Alessandra Santisi, Claudia Columbo, Ludovica Martini, Maria Paola Ronchetti, Luca Di Chiara, Alessandra Toscano, Carlo Gandolfo, Andrea Dotta and Irma Capolupo
    Citation: Italian Journal of Pediatrics 2023 49:141
  3. Periodontal disease and its bacteria can be responsible for pregnancy complications and transmission of periodontal bacteria from mother to newborn.

    Authors: Monica Russo, Maria Grazia Calevo, Gloria D’Alessandro, Matteo Tantari, Marco Migliorati, Ilaria Piccardo, Paola Polo Perucchin and Cesare Arioni
    Citation: Italian Journal of Pediatrics 2023 49:140
  4. Maternal diabetes might be related to a high risk of allergic disease in offspring. However, it remains unknown if maternal gestational diabetes mellitus (GDM) is also associated with a high incidence of child...

    Authors: Xufeng Huang, Zhengguo Huang, Jing Zhang and You Jiang
    Citation: Italian Journal of Pediatrics 2023 49:139
  5. Palpitations represent a common cause for consultation in the pediatric Emergency Department (ED). Unlike adults, palpitations in children are less frequently dependent from the heart, recognizing other causes.

    Authors: Angelica De Nigris, Mattia Arenella, Giangiacomo Di Nardo, Giovanni Maria Di Marco, Annunziata Mormile, Daria Lauretta, Caterina De Simone, Angela Pepe, Rosaria Cosimi, Rossella Vastarella, Antonietta Giannattasio, Giovanni Salomone, Silverio Perrotta, Speranza Cioffi, Pierluigi Marzuillo, Vincenzo Tipo…
    Citation: Italian Journal of Pediatrics 2023 49:137
  6. Retinopathy of prematurity (ROP) is typically treated with laser photocoagulation and/or intravitreal anti-vascular endothelial growth factor (anti-VEGF). To the best of our knowledge, most systematic reviews ...

    Authors: Jing Chen, Qingfei Hao, Jing Zhang, Yanna Du, Haoming Chen and Xiuyong Cheng
    Citation: Italian Journal of Pediatrics 2023 49:136
  7. Children tend to have milder forms of COVID-19 than adults, however post-acute complications have been observed also in the paediatric population. In this study, we compared COVID-19-related outcomes and long-...

    Authors: Chiara Rosazza, Laura Alagna, Alessandra Bandera, Arianna Biffi, Fabiana Ciciriello, Andrea Gramegna, Vincenzina Lucidi, Paola Giovanna Marchisio, Paola Medino, Antonio Muscatiello, Sara Uceda Renteria and Carla Colombo
    Citation: Italian Journal of Pediatrics 2023 49:135
  8. Pancreatic Stone Protein (PSP) is one of the most promising diagnostic and prognostic markers. The aim of the study was to assess the accuracy of PSP, compared to C-Reactive Protein (CRP), and Procalcitonin (P...

    Authors: Gabriella Bottari, Mariangela Caruso, Emanuel Paionni, Maia De Luca, Lorenza Romani, Mara Pisani, Annalisa Grandin, Livia Gargiullo, Giorgio Zampini, Chiara Gagliardi, Danilo Alunni Fegatelli, Annarita Vestri, Laura Lancella, Ottavia Porzio, Andrea Onetti Muda, Alberto Villani…
    Citation: Italian Journal of Pediatrics 2023 49:134
  9. Extubation failure (EF) is a significant concern in mechanically ventilated newborns, and predicting its occurrence is an ongoing area of research. To investigate the predictors of EF in newborns undergoing pl...

    Authors: Maoling Fu, Zhenjing Hu, Genzhen Yu, Ying Luo, Xiaoju Xiong, Qiaoyue Yang, Wenshuai Song, Yaqi Yu and Ting Yang
    Citation: Italian Journal of Pediatrics 2023 49:133
  10. Neuroblastoma is the most frequent extracranial solid tumor occurring in childhood, representing approximately 28% of all cancers diagnosed in infants. Signs and symptoms of neuroblastoma vary with the site of...

    Authors: Carolina Carraro, Marco Rabusin, Flora Maria Murru, Lydie Ammar, Egidio Barbi, Alessandro Amaddeo and Giorgio Cozzi
    Citation: Italian Journal of Pediatrics 2023 49:132
  11. Antibiotic overuse in children is a significant public health concern, as it can lead to the emergence and spread of antibiotic-resistant bacteria. Although respiratory infections account for most antibiotic p...

    Authors: Marina Picca, Romeo Carrozzo, Gregorio Paolo Milani, Antonio Corsello, Marina Macchi, Roberto Buzzetti, Paola Marchisio and Chiara Mameli
    Citation: Italian Journal of Pediatrics 2023 49:131
  12. Authors: Aslan Yilmaz, Yavuz Ozer, Nesrin Kaya, Aydilek Dagdeviren Cakir, Hazal Cansu Culpan, Yildiz Perk, Mehmet Vural and Olcay Evliyaoglu
    Citation: Italian Journal of Pediatrics 2023 49:130

    The original article was published in Italian Journal of Pediatrics 2023 49:105

  13. Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ...

    Authors: Sheng-Hui Tuan, Jin-Hui Chung, Guan-Bo Chen, Shu-Fen Sun, I-Hsiu Liou, Chien-Hui Li and Yi-Ju Tsai
    Citation: Italian Journal of Pediatrics 2023 49:129
  14. COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management...

    Authors: Elena Bozzola, Carlo Caffarelli, Francesca Santamaria and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:128
  15. Beckwith-Wiedemann syndrome (BWS, OMIM #130,650) is a pediatric overgrowth disorder involving a predisposition to tumor development. Although the clinical management of affected patients is well established, i...

    Authors: Pierandrea Elefante, Beatrice Spedicati, Flavio Faletra, Laura Pignata, Flavia Cerrato, Andrea Riccio, Egidio Barbi, Luigi Memo and Laura Travan
    Citation: Italian Journal of Pediatrics 2023 49:127
  16. Early identification of intravenous immunoglobulin (IVIG) resistance contributes to better management of Kawasaki disease (KD). This study aims to establish an effective prediction model for IVIG resistance in...

    Authors: Junjie Wang, Xiaohui Huang and Donghao Guo
    Citation: Italian Journal of Pediatrics 2023 49:126
  17. There are relatively few studies investigating C-C motif chemokine ligand 2 (CCL2) level in bronchoalveolar lavage fluid (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP), and the relationship betw...

    Authors: Jiangwei Zhu, Xue Liu, Xiaowen Zhan, Mengzhu Wang, Yuling Zhang, Li Na and Shujun Li
    Citation: Italian Journal of Pediatrics 2023 49:125
  18. Tumors are rare in neonatal age. Congenital mesoblastic nephroma (CMN) is a usually benign renal tumor observed at birth, or in the first months of life. It may also be identified prenatally and associated wit...

    Authors: Gregorio Serra, Marcello Cimador, Mario Giuffrè, Vincenzo Insinga, Claudio Montante, Marco Pensabene, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:124
  19. Acute viral bronchiolitis is the most common cause of hospitalization in children under 12 months of age. The variable clinical presentation and the potential for sudden deterioration of the clinical condition...

    Authors: Federica Porcaro, Renato Cutrera, Anna Chiara Vittucci and Alberto Villani
    Citation: Italian Journal of Pediatrics 2023 49:123
  20. Headache is one of the most common pain syndromes in the paediatric population. Headaches are classified as primary (migraine, tension-type headaches, trigeminal autonomic cephalalgia and other primary headach...

    Authors: Léa Lenglart, Cécile Monteil, Eugenia Spreafico, Thomas Moulding and Luigi Titomanlio
    Citation: Italian Journal of Pediatrics 2023 49:122
  21. Influenza surveillance aims to determine onset, duration and intensity of the seasonal Influence-like Illness (ILI); data collection begins in the week 42 of a year and ends in the week 17 of the following yea...

    Authors: Stefania Ranno, Luana Coltella, Giulia Linardos, Velia Chiara Di Maio, Luna Colagrossi, Leonarda Gentile, Eugenia Galeno, Marta Luisa Ciofi degli Atti, Sebastian Cristaldi, Alberto Villani, Massimiliano Raponi, Carlo Federico Perno and Cristina Russo
    Citation: Italian Journal of Pediatrics 2023 49:121
  22. We investigated changes in microR-29c and microR-146a expression in the serum of children with Mycoplasma pneumoniae pneumonia, analysed their relationship with inflammatory factors and disease severity, and eval...

    Authors: Jingcai Wang, Chunyan Guo, Lixin Yang, Peng Sun and Xiaoqing Jing
    Citation: Italian Journal of Pediatrics 2023 49:119
  23. While existing research has explored changes in health behaviours among adults and adolescents due to the COVID-19 outbreak, the impact of quarantine on young children’s well-being is still less clear. Moreove...

    Authors: Marco Giustini, Ilaria Luzi, Angela Spinelli, Silvia Andreozzi, Mauro Bucciarelli, Marta Buoncristiano, Paola Nardone and Silvia Ciardullo
    Citation: Italian Journal of Pediatrics 2023 49:118
  24. Ophthalmia neonatorum is an acute conjunctivitis that occurs in newborns within the first month of life. The most serious infections are due to Chlamydia trachomatis and Neisseria gonorrhoeae, that may cause perm...

    Authors: Vito Mondì, Chryssoula Tzialla, Salvatore Aversa, Daniele Merazzi, Stefano Martinelli, Gabriella Araimo, Luca Massenzi, Giacomo Cavallaro, Luigi Gagliardi, Fiammetta Piersigilli, Mario Giuffrè, Simona Lozzi, Paolo Manzoni, Fabio Mosca, Irene Cetin, Vito Trojano…
    Citation: Italian Journal of Pediatrics 2023 49:117
  25. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with different initial symptoms and complex clinical manifestations. A 14-year-old female patient presented with persistent fever and severe h...

    Authors: Yanlin Li, Zhihua Si, Wei Zhao, Cong Xie, Xu Zhang, Ju Liu, Jinzhi Liu and Zhangyong Xia
    Citation: Italian Journal of Pediatrics 2023 49:116
  26. The last year saw intensive efforts to advance knowledge in pediatric medicine. This review highlights important publications that have been issued in the Italian Journal of Pediatrics in 2022. We have chosen ...

    Authors: Carlo Caffarelli, Francesca Santamaria, Ettore Piro, Simona Basilicata, Lorenzo D’Antonio, Bertrand Tchana, Sergio Bernasconi and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:115
  27. Acute pharyngitis is a frequent reason for primary care or emergency unit visits in children. Most available data on pharyngitis management come from primary care studies that demonstrate an underuse of microb...

    Authors: Gregorio P. Milani, Claudio Rosa, Naz Tuzger, Ilaria Alberti, Chiara Ghizzi, Stefania Zampogna, Angela Amigoni, Carlo Agostoni, Diego Peroni, Paola Marchisio and Elena Chiappini
    Citation: Italian Journal of Pediatrics 2023 49:114
  28. SARS-Cov2 infection began to spread worldwide since December 2019; on March 2020, the World Health Organization characterized its related disease, named COVID-19, as a pandemic. In Italy, to contain the spread...

    Authors: Paolo Cavarzere, Romina Pausilli, Lara Nicolussi Prinicpe, Rossella Gaudino, Alessandra Guzzo, Gaetano Cantalupo and Franco Antoniazzi
    Citation: Italian Journal of Pediatrics 2023 49:113
  29. Emerging technologies have demonstrated outstanding potential in improving healthcare, yet their full integration remains a challenge for all medical specialties, including pediatrics. To support the swift imp...

    Authors: Alberto Eugenio Tozzi, Francesco Gesualdo, Elisabetta Pandolfi, Diana Ferro, Giulia Cinelli, Elena Bozzola, Tommaso Aversa, Antonio Di Mauro, Chiara Mameli and Ileana Croci
    Citation: Italian Journal of Pediatrics 2023 49:112
  30. Ataxia-telangiectasia (A-T) is a rare autosomal recessive DNA repair disorder, characterized by progressive cerebellar degeneration, telangiectasia, immunodeficiency, recurrent sinopulmonary infections, radiat...

    Authors: Laura De Nardi, Marco Francesco Natale, Virginia Messia, Paolo Tomà, Fabrizio De Benedetti and Antonella Insalaco
    Citation: Italian Journal of Pediatrics 2023 49:111
  31. Inadequate breastfeeding and complementary feeding practices are key determinants of child malnutrition and impact one-third of the under-five mortality rate worldwide. The district of Namuno in Cabo Delgado (...

    Authors: Kodak Raúl Marroda, Cristiana Berti, Adriano La Vecchia, Carlo Agostoni, Bruno Nazim Baroni, Silvia Bettocchi and Mattia Baglioni
    Citation: Italian Journal of Pediatrics 2023 49:110
  32. Endocan is a soluble dermatan sulfate proteoglycan (50 kDa) secreted by endothelial cells and expressed by dermal, coronary, pulmonary and adipose tissue microvasculature. It plays an important role in the pat...

    Authors: Carmela Morace, Selenia Lorenza Curatola, Giuseppe Mandraffino, Michele Scuruchi, Angela Elvira Serrano’, Angelo Tropeano, Fortunato Lombardo, Giuseppina Salzano, Giovanni Squadrito, Antonio Giovanni Versace and Mariella Valenzise
    Citation: Italian Journal of Pediatrics 2023 49:108
  33. This case of psittacosis in children, is the first described in literature, in Italy. This respiratory infection can be transmitted to humans from the inhalation of respiratory secretions, feces and plumage ae...

    Authors: Serena Marchese, Giacomo Marchese, Giuseppe Paviglianiti, Maria Lapi, Gaetano Ottoveggio, Giuseppe Pipitone and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:107
  34. Transient hypothyroxinemia of prematurity (THOP) is defined as a low level of circulating thyroxine (T4), despite low or normal thyroid-stimulating hormone (TSH) levels. Aims: We aimed to evaluate the incidenc...

    Authors: Aslan Yilmaz, Yavuz Ozer, Nesrin Kaya, Aydilek Dagdeviren Cakir, Hazal Cansu Culpan, Yildiz Perk, Mehmet Vural and Olcay Evliyaoglu
    Citation: Italian Journal of Pediatrics 2023 49:105

    The Correction to this article has been published in Italian Journal of Pediatrics 2023 49:130

  35. The Order of Physicians and Dentists of the Province of Rome aims at focusing on the satisfaction of healthcare personnel as an essential factor for the quality of medical care in the health sector. The aim of...

    Authors: Martina Sapienza, Giuseppe Furia, Domenico Paolo La Regina, Valentina Grimaldi, Maria Grazia Tarsitano, Cristina Patrizi, Giovanni Capelli and Gianfranco Damiani
    Citation: Italian Journal of Pediatrics 2023 49:104
  36. Over 16 million children have been detected positive for the coronavirus disease 2019 (COVID-19) in the United States since the outbreak of the pandemic. In general, children infected with severe acute respira...

    Authors: Jingzhi Wen, Xiaoan Du, Adan Li, Shungeng Zhang, Shengyun Shen, Ziteng Zhang, Liyuan Yang, Changqing Sun, Jianing Li and Shiheng Zhu
    Citation: Italian Journal of Pediatrics 2023 49:103
  37. In this study, we intend to retrospectively analyze the clinical data of postoperative neuroblastoma children, including the results of follow-up examinations and laboratory tests, to explore the clinical valu...

    Authors: Jinmin Li, Zilong Qi, Mo Chen, Jiachen Wang and Xiangyang Liu
    Citation: Italian Journal of Pediatrics 2023 49:102
  38. Ligneous Conjunctivitis (LC) is the most common clinical manifestation of Type I Plasminogen deficiency (T1PD; OMIM# 217090), and it is characterized by the formation of pseudomembranes (due to deposition of f...

    Authors: Filippo Maria Panfili, Paola Valente, Andrea Ficari, Fabiana Cortellessa, Davide Vecchio, Michaela Veronika Gonfiantini, Paola Sabrina Buonuomo, Giovanna Stefania Colafati, Emanuele Agolini, Maria Bartuli, Alessandra Claudia Modugno and Marina Macchiaiolo
    Citation: Italian Journal of Pediatrics 2023 49:101
  39. Diagnosing central precocious puberty (CPP) requires an integrated approach based on clinical, biochemical and instrumental data. The diagnostic gold standard is represented by GnRH (gonadotropin-releasing hor...

    Authors: Ilaria Brambilla, Carmen Guarracino, Carmelo Pistone, Catherine Klersy, Amelia Licari, Gian Luigi Marseglia and Enrico Tondina
    Citation: Italian Journal of Pediatrics 2023 49:100
  40. Neurodevelopmental disorders have a multifactorial etiology, since biological, genetic, psychosocial and environmental risk factors are involved. Recent studies have been linking neurodevelopmental disorders a...

    Authors: Andrea Querzani, Fabio Sirchia, Gianluca Rustioni, Alessandra Rossi, Alessandro Orsini, Gian Luigi Marseglia, Salvatore Savasta, Luisa Chiapparini and Thomas Foiadelli
    Citation: Italian Journal of Pediatrics 2023 49:99
  41. Shwachman-Diamond syndrome (SDS) is a rare congenital disorder caused by mutations in the SBDS gene and characterized by exocrine pancreatic deficiency, hematologic dysfunction, and skeletal growth failure. Al...

    Authors: Lusine V. Navasardyan, Ingrid Furlan, Stephanie Brandt, Ansgar Schulz, Martin Wabitsch and Christian Denzer
    Citation: Italian Journal of Pediatrics 2023 49:98
  42. Basic motor competencies (BMC) play a vital role in child development and are a primary focus of physical education. However, there is a lack of research on BMC in preschool-aged children, making this study pa...

    Authors: Gaizka Legarra-Gorgoñon, Yesenia García-Alonso, Robinson Ramírez-Vélez, Blanca Erice-Echegaray, Mikel Izquierdo and Alicia M. Alonso-Martínez
    Citation: Italian Journal of Pediatrics 2023 49:97
  43. Fusobacterium necrophorum is an anaerobic, gram-negative, non-motile, filamentous, non-spore forming bacillus found in the oral cavity, gastrointestinal tract, and female genital tract, responsible of a rare dise...

    Authors: Laura Venditto, Giuliana Ferrante, Anna Caccin, Giulia Franchini, Marco Zaffanello, Laura Tenero, Michele Piazza, Stefano Di Gioia, Giorgio Piacentini and Angelo Pietrobelli
    Citation: Italian Journal of Pediatrics 2023 49:96
  44. Chronic Granulomatous Disease (CGD) is a primary immunodeficiency that causes susceptibility to recurrent fungal and bacterial infections. The CYBB gene encodes gp91phox component of the Phagocytic Nicotinamide a...

    Authors: Irum Gul, Taj Ali Khan, Noor ul Akbar, Naila Gul, Rehman Ali and Shahid Niaz Khan
    Citation: Italian Journal of Pediatrics 2023 49:95
  45. Primary adrenal insufficiency (PAI) in childhood is a life-threatening disease most commonly due to impaired steroidogenesis. Differently from adulthood, autoimmune adrenalitis is a rare condition amongst PAI’...

    Authors: Marta Arrigoni, Paolo Cavarzere, Lara Nicolussi Principe, Rossella Gaudino and Franco Antoniazzi
    Citation: Italian Journal of Pediatrics 2023 49:94
  46. Multiple immunopathological responses to viruses are observed in infectious mononucleosis (IM), a manifestation of primary infection with Epstein-Barr virus (EBV). Protective effects of the negative immunoregu...

    Authors: Mingsheng Zhao, Li Ma, Huihui Jiang, Yufeng Gu, Xin Yang, Riming Liu, Chengming Sun and Yulan Li
    Citation: Italian Journal of Pediatrics 2023 49:93

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