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  1. Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We unde...

    Authors: Marco Pensabene, Maria Rita Di Pace, Fabio Baldanza, Francesco Grasso, Maria Patti, Maria Sergio, Simona La Placa, Mario Giuffre’, Gregorio Serra, Alessandra Casuccio and Marcello Cimador
    Citation: Italian Journal of Pediatrics 2022 48:140
  2. Primary Synovial Chondromatosis (PSC) is a rare benign tumor of the synovial membrane in which cartilage metaplasia produces calcific loose bodies within the articular space. Only a few cases are reported in t...

    Authors: Matteo Trevisan, Luca Di Lenarda, Serena Pastore, Alessia Saccari, Gianluca Canton, Umberto Lucangelo, Andrea Taddio and Luigi Murena
    Citation: Italian Journal of Pediatrics 2022 48:139
  3. Recent research has documented the potential associations existing between the use of social media (SM) and the occurrence/development and treatment of Eating Disorders (ED). However, the literature directly a...

    Authors: Jacopo Pruccoli, Marta De Rosa, Lucia Chiasso, Annalisa Perrone and Antonia Parmeggiani
    Citation: Italian Journal of Pediatrics 2022 48:138
  4. Considering the destructive effects of malnutrition on the growth, development, and health of children and the importance of identifying the factors affecting it, the present study aimed to investigate the sta...

    Authors: Mina Maheri, Maryam Bidar, Hamidreza Farrokh-Eslamlou and Ali Sadaghianifar
    Citation: Italian Journal of Pediatrics 2022 48:137
  5. The COVID-19 pandemic has dramatically affected healthcare professionals’ lives. We investigated the potential mental health risk faced by healthcare professionals working in neonatal units in a multicentre cr...

    Authors: Luigi Gagliardi, Serena Grumi, Marzia Gentile, Roberta Cacciavellani, Giulia Placidi, Angelina Vaccaro, Claudia Maggi, Beatrice Gambi, Letizia Magi, Laura Crespin, Graziano Memmini, Marcello DeFilippo, Elena Verucci, Liliana Malandra, Laura Mele, Angelo Azzarà…
    Citation: Italian Journal of Pediatrics 2022 48:136
  6. Childhood obesity is associated with impaired Quality-of-Life (QoL), increased stigmatization and higher risk of development of depression compared to their peers. This report describes the long-term developme...

    Authors: Rasmus Møller Jørgensen, Esben Thyssen Vestergaard, Britta Kremke, Rikke Frederiksen Bahnsen, Bent Windelborg Nielsen and Jens Meldgaard Bruun
    Citation: Italian Journal of Pediatrics 2022 48:135
  7. Authors: Adriano La Vecchia, Giulio Ippolito, Vittoria Taccani, Elisabetta Gatti, Patrizia Bono, Silvia Bettocchi, Raffaella Pinzani, Claudia Tagliabue, Samantha Bosis, Paola Marchisio and Carlo Agostoni
    Citation: Italian Journal of Pediatrics 2022 48:134

    The original article was published in Italian Journal of Pediatrics 2022 48:67

  8. Arthrogryposis multiplex congenita (AMC) is a group of clinically and etiologically heterogeneous conditions, characterized by prenatal onset contractures affecting two or more joints. Its incidence is about 1...

    Authors: Gregorio Serra, Vincenzo Antona, Chiara Cannata, Mario Giuffrè, Ettore Piro, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:133
  9. Congenital maxillomandibular syngnathia is a rare craniofacial anomaly leading to difficulties in feeding, breathing and ability to thrive. The fusion may consist of soft tissue union (synechiae) to hard tissu...

    Authors: Ingrid Anne Mandy Schierz, Salvatore Amoroso, Vincenzo Antona, Mario Giuffrè, Ettore Piro, Gregorio Serra and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:132
  10. Congenital hypothyroidism (CH) is the most frequent congenital endocrine disorder. The purpose of the present study was to evaluate the incidence and etiological classification of CH in Apulia in a three-year ...

    Authors: Simonetta Simonetti, Gabriele D’Amato, Benedetta Esposito, Mariangela Chiarito, Domenico Dentico, Tania Lorè, Roberta Cardinali, Silvia Russo, Nicola Laforgia and Maria Felicia Faienza
    Citation: Italian Journal of Pediatrics 2022 48:131
  11. The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should a...

    Authors: Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio and Claudia Colomba
    Citation: Italian Journal of Pediatrics 2022 48:130
  12. We proposed to analyze thoroughly the impact of the COVID-19 lockdown (CL) in changes of profiles and in trend of the domestic accidents (DAs) in children.

    Authors: Valentina Ferro, Raffaella Nacca, Mara Pisani, Sebastian Cristaldi, Maria Francesca Faa, Maria Chiara Supino, Umberto Raucci, Antonino Reale, Marta Ciofi Degli Atti, Massimiliano Raponi, Alberto Villani and Anna Maria Musolino
    Citation: Italian Journal of Pediatrics 2022 48:129
  13. Leukoencephalopathy with vanishing white matter (VWM) is an autosomal recessive neurological disease. The physiopathology of disease is still little understood, but it seems to involve impairment in maturation...

    Authors: Ilaria Filareto, Giulia Cinelli, Ilaria Scalabrini, Elisa Caramaschi, Patrizia Bergonzini, Elisabetta Spezia, Alessandra Todeschini and Lorenzo Iughetti
    Citation: Italian Journal of Pediatrics 2022 48:128
  14. According to the latest version of the Diagnostic and Statistical Manual of Mental Disorders, somatic symptom and related disorders (SSRDs) are defined as psychopathological manifestations characterized by phy...

    Authors: Roberta Sartori, Antimo Tessitore, Aurora Della Torca and Egidio Barbi
    Citation: Italian Journal of Pediatrics 2022 48:127
  15. Quarantine and isolation measures during COVID-19 pandemic may have caused additional stress and challenged the mental health of the youth. Aim of the study is to investigate the COVID-19 pandemic impact on ne...

    Authors: Elena Bozzola, Pietro Ferrara, Giulia Spina, Alberto Villani, Marco Roversi, Massimiliano Raponi, Giovanni Corsello and Annamaria Staiano
    Citation: Italian Journal of Pediatrics 2022 48:126
  16. Neurological vertigo is a common symptom in children and adults presenting to the emergency department (ED) and its evaluation may be challenging, requiring often the intervention of different medical specialt...

    Authors: Noemi Pellegrino, Vincenzo Di Stefano, Eleonora Rotondo, Alessandro Graziosi, Marianna Gabriella Rispoli, Angelo Torrente, Antonino Lupica, Filippo Brighina, Umberto Raucci and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:125
  17. Ventricular septal defects (VSDs) are one of the leading causes of death due to cardiac anomalies during the first months of life. The prevalence of VSD in neonates is reported up to 4%. Despite the remarkable...

    Authors: Sumbal Sarwar, Shabana, Amna Tahir, Zainab Liaqat, Saher Naseer, Rani Summeya Seme, Sabahat Mehmood, Saleem Ullah Shahid and Shahida Hasnain
    Citation: Italian Journal of Pediatrics 2022 48:124
  18. Albright’s hereditary osteodystrophy (AHO) is an inherited disorder which is caused by an inactivating variant in the GNAS gene. AHO appears associated to either pseudohypoparathyroidism 1a (PHP1a) when GNAS gene...

    Authors: Qing Zhou, Bin Liang, Qing-Xian Fu, Hui Liu and Chao-Chun Zou
    Citation: Italian Journal of Pediatrics 2022 48:123
  19. With the increasing incidence of asymptomatic carriers or milder symptoms, children and adolescents are likely to become a silent source of infection. In view of the efficacy and safety of vaccines in the trea...

    Authors: Lin Wang, Wen Wen, Chen Chen, Jiake Tang, Chunyi Wang, Mengyun Zhou, Yongran Cheng, Xingwei Zhang, Mingwei Wang, Zhanhui Feng and Weiqian Wang
    Citation: Italian Journal of Pediatrics 2022 48:122
  20. Prader-Willi syndrome (PWS) is a complex disorder caused by impaired paternally expressed genes on chromosome 15q11-q13. Variable findings have been reported about the phenotypic differences among PWS genetic ...

    Authors: Lu Zhang, Xiaoliang Liu, Yunjing Zhao, Qingyi Wang, Yuanyuan Zhang, Haiming Gao, Bijun Zhang, Wanting Cui and Yanyan Zhao
    Citation: Italian Journal of Pediatrics 2022 48:121
  21. The bacterial load of the human lower respiratory tract is at least several times lower than that of the other parts of the body. This study aimed to identify the bacterial composition and colony structure of ...

    Authors: Jiawei Yao, Tao Ai, Wanmin Xia, Yinghong Fan, Cheng Xie and Lei Zhang
    Citation: Italian Journal of Pediatrics 2022 48:120
  22. E-cigarettes are devices which allow to aerosolize liquids containing nicotine or other substances. Ever since they were released on the market in 2006, the number of users have been constantly increasing, esp...

    Authors: Chiara Casamento Tumeo, Alessandra Schiavino, Maria Giovanna Paglietti, Francesca Petreschi, Alessandra Ottavianelli, Alessandro Onofri, Claudio Cherchi, Paolo Tomà and Renato Cutrera
    Citation: Italian Journal of Pediatrics 2022 48:119
  23. The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life ...

    Authors: Antonella Riva, Elisabetta Amadori, Maria Stella Vari, Alberto Spalice, Vincenzo Belcastro, Maurizio Viri, Donatella Capodiferro, Antonino Romeo, Alberto Verrotti and Pasquale Striano
    Citation: Italian Journal of Pediatrics 2022 48:118
  24. Preterm extremely low birth weight infants (ELBWi) are known to be at greater risk of developing neuropsychiatric diseases. Identifying early predictors of outcome is essential to refer patients for early inte...

    Authors: Camilla Caporali, Stefania Longo, Giovanna Tritto, Gianfranco Perotti, Camilla Pisoni, Cecilia Naboni, Barbara Gardella, Arsenio Spinillo, Federica Manzoni, Stefano Ghirardello, Renato Borgatti and Simona Orcesi
    Citation: Italian Journal of Pediatrics 2022 48:117
  25. Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodi...

    Authors: Maria Carolina Colucci, Marica Fabiana Triolo, Simona Petrucci, Flaminia Pugnaloni, Massimiliano Corsino, Melania Evangelisti, Maria Cecilia D’Asdia, Giovanni Di Nardo, Matteo Garibaldi, Gianluca Terrin and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:116
  26. It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.

    Authors: Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano and Cristina Pederiva
    Citation: Italian Journal of Pediatrics 2022 48:115
  27. Despite simple and proven cost-effective measures were available to prevent birth asphyxia; studies suggested that there has been limited progress in preventing birth asphyxia even in healthy full-term neonate...

    Authors: Masresha Asmare Techane, Tewodros Getaneh Alemu, Chalachew Adugna Wubneh, Getaneh Mulualem Belay, Tadesse Tarik Tamir, Addis Bilal Muhye, Destaye Guadie Kassie, Amare Wondim, Bewuketu Terefe, Bethelihem Tigabu Tarekegn, Mohammed Seid Ali, Beletech Fentie, Almaz Tefera Gonete, Berhan Tekeba, Selam Fisiha Kassa, Bogale Kassahun Desta…
    Citation: Italian Journal of Pediatrics 2022 48:114
  28. Studies published on gender-related differences in the gambling behavior of adolescents have focused mainly on psychological and social factors. The aim of this study was to develop separate risk factor models...

    Authors: Alessandra Buja, Milena Sperotto, Bruno Genetti, Paolo Vian, Fabio Vittadello, Elisabetta Simeoni, Chiara Zampieri and Vincenzo Baldo
    Citation: Italian Journal of Pediatrics 2022 48:113
  29. Autism spectrum disorder (ASD) is one of the serious developmental disorders that is usually diagnosed below the age of three years. Although the severity of the disease’s symptoms varies from patient to patie...

    Authors: Nader Salari, Shabnam Rasoulpoor, Shna Rasoulpoor, Shamarina Shohaimi, Sima Jafarpour, Nasrin Abdoli, Behnam Khaledi-Paveh and Masoud Mohammadi
    Citation: Italian Journal of Pediatrics 2022 48:112
  30. Cathelicidin/LL-37 plays a significant role in the human immune defense reaction. Preterm human immature organs being exposed to inflammation-induced injury was the critical denominator leading to the common p...

    Authors: Zhuxiao Ren, Wenhui Mo, Liling Yang, Jianlan Wang, Qi Zhang, Zhicheng Zhong, Wei Wei, Zhipeng Liu, Zhiping Wu, Yao Yao and Jie Yang
    Citation: Italian Journal of Pediatrics 2022 48:111
  31. Available guidelines for asthma management represent an important and suitable tool to make the entire medical process evidence-based, effective, and safe for patients. Their purpose is to help doctors and pat...

    Authors: Elio Novembre, Mattia Giovannini, Simona Barni and Francesca Mori
    Citation: Italian Journal of Pediatrics 2022 48:110
  32. The potential use of biomarkers in the diagnosis of fungal infections is a challenge. The aim of this study was to evaluate the role of a biomarker-guided antifungal stewardship program for hospitalized pediat...

    Authors: Parisa Badiee, Ali Amanati, Fatemeh Ghasemi and Hadis Jafarian
    Citation: Italian Journal of Pediatrics 2022 48:109
  33. Adolescence is characterized by emotional instability and risk-taking behaviours that can lead to, among other things, an increased risk of developing pathological video-gaming and gambling habits. The aim of ...

    Authors: Loredana Cena, Matteo Rota, Stefano Calza, Alice Trainini, Sara Zecca, Sofia Bonetti Zappa, Luisa Silvia Nodari and Alberto Stefana
    Citation: Italian Journal of Pediatrics 2022 48:108
  34. Myogenic Arthrogryposis Multiplex Congenita type 3 (AMC-3), is a rare congenital condition characterized by severe hypotonia, club feet, and multiple joint contractures often affecting both arms and legs which...

    Authors: Naglaa M. Kamal, AlaaEddin M. Alzeky, Maher R. Omair, Ruwayd A. Attar, Abdullah M. Alotaibi, Abdullah Safar, Nawal S. Alosaimi and Sara A. S. Abosabie
    Citation: Italian Journal of Pediatrics 2022 48:107
  35. The assessment of body composition is central in diagnosis and treatment of paediatric obesity, but a criterion method is not feasible in clinical practice. Even the use of bioelectrical impedance analysis (BI...

    Authors: Maria Rosaria Licenziati, Giada Ballarin, Gabriella Iannuzzo, Maria Serena Lonardo, Olivia Di Vincenzo, Arcangelo Iannuzzi and Giuliana Valerio
    Citation: Italian Journal of Pediatrics 2022 48:106
  36. Beta thalassemia major (β-TM) is a common cause of skeletal morbidity and is associated with increased bone fracture risk, particularly in inadequately transfused children. The aim of this study was to investi...

    Authors: Tanju Çelik, Özlem Sangün, Şule Ünal, Ali Balcı and Sedat Motor
    Citation: Italian Journal of Pediatrics 2022 48:105
  37. To investigate the coping strategies of a group of adolescents with somatic symptom disorder compared to non-somatic symptom disorder peers during the COVID-19 related lockdown.

    Authors: Andrea Trombetta, Laura De Nardi, Giorgio Cozzi, Luca Ronfani, Lara Bigolin, Egidio Barbi, Matteo Bramuzzo and Giuseppe Abbracciavento
    Citation: Italian Journal of Pediatrics 2022 48:104
  38. Phototherapy (PT) is the most often utilized technique for treating and preventing severe hyperbilirubinemia in the term and preterm newborns. PT's proven benefit is that it decreases the requirement for excha...

    Authors: Mai Rabie El-Sheikh, Amira Youssef Ahmed, Abd EL-Rahman Mohamed ELMashad, Ibrahim Ibrahim Talaye and Eslam El-Sayed El-Hawary
    Citation: Italian Journal of Pediatrics 2022 48:103
  39. Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although many reports have detailed a range of neurological symptoms in SARS-C...

    Authors: Martina Capponi, Bianca Laura Cinicola, Giulia Brindisi, Cristiana Alessia Guido, Maria Cristina Torcé, Anna Maria Zicari and Alberto Spalice
    Citation: Italian Journal of Pediatrics 2022 48:102
  40. Multiple gestations represent a considerable proportion of pregnancies delivering in the late preterm (LP) period. Only 30% of LP twins are due to spontaneous preterm labor and 70% are medically indicated; amo...

    Authors: Francesca Monari, Giuseppe Chiossi, Michela Ballarini, Daniela Menichini, Giancarlo Gargano, Alessandra Coscia, Dante Baronciani and Fabio Facchinetti
    Citation: Italian Journal of Pediatrics 2022 48:101
  41. In our third-level Neonatal Unit in Northern Italy, we recorded a high rate of neonatal hyperbilirubinemia requiring phototherapy in March-November 2020, during the first phase of COVID-19 pandemic, compared t...

    Authors: Alice Monzani, Valentino Remorgida and Ivana Rabbone
    Citation: Italian Journal of Pediatrics 2022 48:100
  42. Brain abscesses are uncommon but life-threatening in extremely preterm (EP, Gestational Age < 28 weeks) infants. The information of long-time follow-up is rare, but very few cases presented almost intact neura...

    Authors: Shulin Pan, Su Lin, Jing Lin, Shangqin Chen and Zhenlang Lin
    Citation: Italian Journal of Pediatrics 2022 48:99
  43. The use of electronic cigarettes (e-cigarette) and vaping devices started as a potential aid for cessation and reducing the harmful consequences of cigarette smoking, mainly in the adult population. Today e-ci...

    Authors: Fabrizio Virgili, Raffaella Nenna, Shira Ben David, Enrica Mancino, Greta Di Mattia, Luigi Matera, Laura Petrarca and Fabio Midulla
    Citation: Italian Journal of Pediatrics 2022 48:97
  44. Although Anorexia Nervosa (AN) patients show dysfunctional behaviour in information processing, visual and verbal memory performance, and different cognitive fields, regardless of their BMI, the literature on ...

    Authors: Salvatore Ferdinando Aruta, Jacopo Pruccoli, Nicole Bandini, Paola Rucci and Antonia Parmeggiani
    Citation: Italian Journal of Pediatrics 2022 48:96
  45. Currently, there are a few detailed guidelines on the overall management of children and adolescents with moderate-severe atopic dermatitis. AD ​​is a complex disease presenting with different clinical phenoty...

    Authors: Elena Galli, Anna Belloni Fortina, Giampaolo Ricci, Nunzia Maiello, Iria Neri, Ermanno Baldo, Irene Berti, Domenico Bonamonte, Lucetta Capra, Elena Carboni, Rossella Carello, Francesca Caroppo, Giovanni Cavagni, Iolanda Chinellato, Francesca Cipriani, Pasquale Comberiati…
    Citation: Italian Journal of Pediatrics 2022 48:95
  46. Autoimmune encephalitis (AE) is a type of encephalopathy mediated by an antigenic immune response in the central nervous system. Most research related to autoimmune encephalitis (AE) is focused on early diagno...

    Authors: Jin-Yue Huang, Wen-Xuan Fan, Jing Meng, Chun-Quan Cai and Dong Li
    Citation: Italian Journal of Pediatrics 2022 48:94
  47. COVID toes or chilblain-like skin lesions have been widely reported during COVID-19 pandemic. Most cases were described in patients with negative microbiological tests for SARS-CoV-2, therefore the possible re...

    Authors: Roberto Paparella, Luigi Tarani, Enrico Properzi, Francesco Costantino, Chiara Saburri, Roberta Lucibello, Antonio Richetta, Alberto Spalice and Lucia Leonardi
    Citation: Italian Journal of Pediatrics 2022 48:93
  48. Evidence suggests that many parents who care for their children with cancer are affected by the care burden due to the chronic nature of the disease. The aim of this study was to determine the burden of care l...

    Authors: Mahnaz Chaghazardi, Maryam Janatolmakan, Shahab Rezaeian and Alireza Khatony
    Citation: Italian Journal of Pediatrics 2022 48:92
  49. In this study, we used the novel DeepGestalt technology powered by Face2Gene (FDNA Inc., MA, USA) in suggesting a correct diagnosis based on the facial gestalt of well-known multiple anomaly syndromes. Only mo...

    Authors: Giulia Pascolini, Mauro Calvani and Paola Grammatico
    Citation: Italian Journal of Pediatrics 2022 48:91

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