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Table 2 The clinical characteristics of blood transfusion-dependant-thalassemia major patients.

From: Renal functions in pediatric patients with beta-thalassemia major: relation to chelation therapy: original prospective study

Parameters

All patients

Patients subgroups

P-value <

 

(n = 69)

With chelation

[Group I]

(n = 34)

Without chelation

[Group II]

(n = 35)

 

Disease onset age (months)

13.74 ± -14.55

(2.00-60.00)

12.59 ± 12.77

(2.00-60.00)

14.86 ± 16.21

(2.00-60.00)

0.202

Disease duration (months)

87.42 ± 42.95

(3.00-180.00)

103.21 ± 38.95

(26.00-180.00)

72.09 ± 41.34

(3.00-174.00)

0.991

1st blood transfusion onset (months)

13.74 ± 14.55

(2.00-60.00)

12.59 ± 12.77

(2.00-60.00)

14.86 ± 16.21

(2.00-60.00)

0.202

Blood transfusions/year

9.68 ± 2.96

(6.00-15.00)

9.65 ± 2.79

(6.00-12.00)

9.71 ± 3.16

(6.00-15.00)

0.202

Splenectomy

40 (58.00%)

23 (67.60%)

17 (48.90%)

0.464

Splenectomy duration (months)

37.75 ± 22.43

(3.00-96.00)

42.87 ± 20.76

(12.00-96.00)

30.82 ± 23.35

(3.00-84.00)

0.087

Duration between splenectomy & 1st blood transfusion (months)

62.10 ± 35.28

(6.00-150.00)

69.48 ± 33.16

(6.00-137.00)

52.12 ± 36.57

(6.00-150.00)

0.520

Puberty age (years)

12.28 ± 0.46

(12.00-13.00)

12.17 ± 0.39

(12.00-13.00)

12.50 ± 0.55

(12.00-13.00)

0.055

Positive family history

13 (18.80%)

9 (26.50%)

4 (11.40%)

0.098

  1. Data presented are mean +/- SD (range) or number (%); P-value, significance between patients with and without chelation therapy.