Parameters | All patients | Patients subgroups | P-value < | |
---|---|---|---|---|
 | (n = 69) | With chelation [Group I] (n = 34) | Without chelation [Group II] (n = 35) |  |
Disease onset age (months) | 13.74 ± -14.55 (2.00-60.00) | 12.59 ± 12.77 (2.00-60.00) | 14.86 ± 16.21 (2.00-60.00) | 0.202 |
Disease duration (months) | 87.42 ± 42.95 (3.00-180.00) | 103.21 ± 38.95 (26.00-180.00) | 72.09 ± 41.34 (3.00-174.00) | 0.991 |
1st blood transfusion onset (months) | 13.74 ± 14.55 (2.00-60.00) | 12.59 ± 12.77 (2.00-60.00) | 14.86 ± 16.21 (2.00-60.00) | 0.202 |
Blood transfusions/year | 9.68 ± 2.96 (6.00-15.00) | 9.65 ± 2.79 (6.00-12.00) | 9.71 ± 3.16 (6.00-15.00) | 0.202 |
Splenectomy | 40 (58.00%) | 23 (67.60%) | 17 (48.90%) | 0.464 |
Splenectomy duration (months) | 37.75 ± 22.43 (3.00-96.00) | 42.87 ± 20.76 (12.00-96.00) | 30.82 ± 23.35 (3.00-84.00) | 0.087 |
Duration between splenectomy & 1st blood transfusion (months) | 62.10 ± 35.28 (6.00-150.00) | 69.48 ± 33.16 (6.00-137.00) | 52.12 ± 36.57 (6.00-150.00) | 0.520 |
Puberty age (years) | 12.28 ± 0.46 (12.00-13.00) | 12.17 ± 0.39 (12.00-13.00) | 12.50 ± 0.55 (12.00-13.00) | 0.055 |
Positive family history | 13 (18.80%) | 9 (26.50%) | 4 (11.40%) | 0.098 |