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Table 2 Ammonium chloride loading test profile

From: Relationship between rickets and incomplete distal renal tubular acidosis in children

 

urine pH > 5.5

urine pH < 5.5

2t-test at 95% CI (p)

n (%)

19 (38.00%)

31(62.00%)

 

Urine pH, mean (SD) range

6.40 (0.45) 5.7 -7.50

5.10 (0.32) 4.62 - 5.48

11.9275(< 0.001)

Preloading mean(SD) and range of serum HCO3,

19 (0.02), 19 - 20 mmol/L

22 0(0.461)., 22-24 mmol/L.

28.2313 (< 0.001)

3 hours post loading with NH4CL mean(SD) and range of serum HCO3

16 (0.34), 14 - 16 mmol/L

22 (0.58), 21-23 mmol/L

40.893 (< 0.001)

Rate of reduction of HCO3 from pre loading

to 3 hours post loading

3-5 mmol/L

1-2 mmol/L

 

24 hours urine calcium mean (SD)

1.62 (0.13)mmol/kg/day

0.12 (0.03)mmol/kg/day

20.4594 (< 0.001)