Table 2 Genotypes and allele frequencies of the polymorphisms of the NOS genes in RDS and control groups and their association with the risk of RDS
Genotypes/Alleles | Control group (n = 227) n (%) | RDS group (n = 189) n (%) | P value | OR (95% CI) |
|---|---|---|---|---|
rs2682826 (NOS1) | ||||
GG | 99 (43.6) | 86 (45.5) | ||
GA | 107 (47.1) | 75 (39.7) | 0.308 | 0.807 (0.534–1.200) |
AA | 21 (9.3) | 28 (14.8) | 0.201 | 1.535 (0.813–2.897) |
G allele | 305 (67.2) | 247 (65.3) | ||
A allele | 149 (32.8) | 131 (34.7) | 0.577 | 1.086 (0.814–1.449) |
rs1799983 (NOS3) | ||||
GG | 134 (59.0) | 127 (67.2) | ||
GT | 88 (38.8) | 57 (30.2) | 0.070 | 0.683 (0.453–1.032) |
TT | 5 (2.2) | 5 (2.6) | 1.000 | 1.055 (0.298–3.731) |
G allele | 356 (78.4) | 311 (82.3) | ||
T allele | 98 (21.6) | 67 (17.7) | 0.164 | 0.783 (0.554–1.106) |