Table 1 Etiopathogenesis of infantile colic
Main factors | Related factors |
|---|---|
Immaturity of nervous/digestive system | Family tension |
Cow’s milk proteins allergy and atopy | Maternal smoking |
Altered gut microflora (low Lactobacilli, increased E.coli) | Increased maternal age |
Gut hormones (increased ghrelin and motilin) | Firstborn status |