SHC (n = 14) | WBC (n = 10) | Mild HIE (n = 7) | Control (n = 9) | P | |
---|---|---|---|---|---|
Gestational age (weeks) | 38.6 ± 1.1 | 38.9 ± 1.0 | 38.8 ± 1.1 | 38.8 ± 0.8 | 0.931 |
Birth weight (g) | 3183 ± 501 | 3218 ± 445 | 3410 ± 306 | 3081 ± 289 | 0.480 |
Head circumference (cm) | 34.7 ± 1.1 | 34.7 ± 0.7 | 34.5 ± 1.0 | 34.6 ± 0.6 | 0.945 |
Male | 4 (28.6) | 3 (30.0) | 2 (28.6) | 4 (44.4) | 0.905 |
Delivery via cesarean section | 2 (14.3) | 4 (40.0) | 2 (28.6) | 3 (33.3) | 0.512 |
Birth in the treatment center | 1 (7.1) a | 0 (0.0) a | 0 (0.0) a | 7 (77.8) b | <0.001 |
Age at group randomization (h) | 5.4 ± 1.6 | 5.9 ± 0.3 | 5.3 ± 1.1 | 4.6 ± 1.9 | 0.225 |
Rectal temperature at group randomization (°C) | 34.1 ± 0.9 | 34.4 ± 1.3 | NA | NA | 0.615 |
Existence of clinical convulsions | 13 (92.9) a | 9 (90.0) a | 0 (0.0) b | 0 (0.0) b | <0.001 |
Invasive mechanical ventilation | 13 (92.9) a | 9 (90.0) a | 2 (28.6) b | 0 (0.0) b | <0.001 |
5-min Apgar score (n = 35) | |||||
0–3 | 5 (50.0) | 4 (40.0) | 0 (0.0) | 0 (0.0) | |
4–6 | 5 (50.0) | 6 (60.0) | 5 (83.3) | 0 (0.0) | |
7–10 | 0 (0.0) | 0 (0.0) | 1 (16.7) | 9 (100) | |
10-min Apgar score (n = 24) | |||||
0–3 | 1 (14.3) | 3 (75.0) | 0 (0.0) | 0 (0.0) | |
4–6 | 6 (85.7) | 1 (25.0) | 1 (25.0) | 0 (0.0) | |
7–10 | 0 (0.0) | 0 (0.0) | 3 (75) | 9 (100) | |
Blood gas analysis within 1 h post birth | |||||
pH | 6.9 ± 0.2a | 7.0 ± 0.1a | 7.0 ± 0.1a | 7.30 ± 0.1b | 0.001 |
Base excess (mmol L−1) | −17.7 ± 2.9a | −19.6 ± 1.2a | −17.8 ± 8.9a | −2.6 ± 1.3b | <0.001 |
aEEG before randomization | |||||
Normal | 0 (0.0) | 0 (0.0) | 7 (100) | NA | <0.001 |
Moderate abnormality | 3 (21.4) | 1 (10.0) | 0 (0.0) | NA | |
Severe abnormality | 11 (78.6) | 9 (90.0) | 0 (0.0) | NA | |
Sarnat stage | |||||
Stage I | 0 (0.0) | 0 (0.0) | 7 (100) | NA | <0.001 |
Stage II | 3 (21.4) | 1 (10.0) | 0 (0.0) | NA | |
Stage III | 11 (78.6) | 9 (90.0) | 0 (0.0) | NA |