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Table 4 Combined effects of rs2164331, rs6738266, and rs309143 on isolated VSD

From: Association of DARS gene polymorphisms with the risk of isolated ventricular septal defects in the Chinese Han population

Number of risk allelesa

Case (%)

Control (%)

OR (95% CI)b

P b

0-2

231 (27.47)

949 (32.14)

1.00

 

3

68 (8.08)

276 (9.35)

1.01(0.75-1.37)

9.37 × 10-1

4

361 (42.93)

1219 (41.28)

1.22 (1.01-1.47)

3.8 × 10-2

≥5

181(21.52)

509(17.24)

1.46(1.17-1.83)

1.0 × 10-3

Trend

   

6.37 × 10-4

  1. ars2164331 A, rs6738266 A, rs309143 G were assumed as risk alleles
  2. bCalculated by additive model