Table 3 Phosphate and vitamin D supplementation in severe acute hypophosphatemia

Oral phosphate salts at a dose of 30–40 mg/kg body weight per day, administered in 4–5 doses.

Cholecalciferol (vitamin D3) at a dose of 800–1000 U/day (increase the dose in case of deficiency).

Intravenous phosphate solution at the following doses:

 - 0.08 mmol/kg body weight for 6 h, recommended for short-term hypophosphatemia without complications;

 - 0.16 mmol/kg body weight for long-term hypophosphatemia; or

 - In some cases, doses up to 0.4–0.5 mmol/kg body weight for 6 h are required, up to a maximum dose of 50 mmol of phosphate.