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Table 1 Clinical and laboratory features of CPP girls. All continuous variables are expressed as median (IQR25-IQR75)

From: Molecular screening of PROKR2 gene in girls with idiopathic central precocious puberty

Age at diagnosis, years

6.0(5.0–6.5)

Age at thelarche occurrence, years

5.6 (4.2–5.8)

PH ≥ 2, N (%)

17 (54.8%)

B > 2, N (%)

12 (38.7%)

Height SDS

0.89 (−0.18 to 1.43)

BMI SDS

0.47 (−0.24 to 0.82)

Δ bone age – chronological age, years

2.66 (1.75–3.45)

Basal LH, IU/L

0.8 (0.4–2.4)

Basal FSH, IU/L

3.9 (3.4–5.1)

Basal E2, pg/mL

16 (11–27.7)

Peak LH, IU/L

11.3(8.2–26.7)

  1. PH pubic hair Tanner stage, N raw numbers, B breast Tanner stage, E2 estradiol