Symptoms | Number of eosinophils per fielda | |
---|---|---|
Eosinophilic esophagitis | Growth retardation, feeding difficulties, abdominal pain, non-specific symptoms of gastroesophageal reflux, recurrent vomiting, dysphagia and esophageal food impaction. | ≥15/HPF |
Eosinophilic gastroenteritis | Mucosal form: abdominal pain, vomiting, nausea, dyspepsia, diarrhea, malabsorption, protein-dispersing enteropathy with subsequent weight loss, anemia and hypoalbuminemia. Muscle form: reduced gastric motility, stiffening of the affected tract and possible intestinal obstruction. Serum form: irritation of the peritoneum with eosinophilic ascites, peritonitis and in the most severe cases intestinal perforation. | ≥ 30/5 HPF at the gastric level ≥50/HPF at the duodenal level |
Eosinophilic colitis | Abdominal pain, diarrhea and/or constipation, rectorrhagia, risk of acute complications such as volvulus and intussusception. | ≥50/2 HPF or 100/HPF for cecum and ascending colon ≥42/2 HPF or 84/HPF for transverse colon and descending colon ≥32/2 HPF or 64/HPF for rectum and sigma |