Table 4 Diagnostic performance of biomarkers including median time of five timepoints (T1 = day 1, T2 = day 2, T3 = day 3, T4 = day 5, T5 = day 7) and the median of timepoint 1 (T1 = day 1) in distinguishing sepsis patients from non sepsis patients

PSP Median value

0.636

(0.457–0.815)

166.0

0.54

(0.32, 0.75)

0.83

(0.58, 0.96)

0.80

(0.51, 0.95)

0.60

(0.38, 0.78)

3.7

(1.2, 11.2)

C-RP

Median value

0.503

(0.316–0.689)

7.08

0.45

(0.24, 0.67)

0.72

(0.46, 0.90)

0.66

(0.38, 0.88)

0.52

(0.31, 0.72)

2.0

(0.83, 4.8)

PCT

Median value

0.722

(0,556–0.888)

1.6

0.63

(0.40, 0.82)

0.83

(0.58, 0.96)

0.82

(0.56, 0.96)

0.65

(0.42, 0.83)

4.67

(1.58, 13.77)

PSP T1

0.739

(0.578–0.899)

167.0

0.59

(0.36, 0.79)

0.83

(0.58, 0.96)

0.81

(0.54, 0.96)

0.62

(0.40 0.81)

2.80

(1.24, 6.30)

C-RP

T1

0.468

(0.284–0.653)

6.2

0.54

(0.32, 0.75)

0.55

(0.30, 0.78)

0.60

(0.36, 0.80)

0.50

(0.27, 0.72)

1.50

(0.79, 2.86)

PCT

T1

0.754

(0.583–0.924)

1.1

0.71

(0.47, 0.88)

0.76

(0.50, 0.93)

0.78

(0.54, 0.93)

0.68

(0.43, 0.87)

3.20

(1.47, 6.96)