Table 5 Diagnostic performance of biomarkers including median of five timepoints (T1 = day 1, T2 = day 2, T3 = day 3, T4 = day 5, T5 = day 7) in distinguishing survival from no survival in paediatric patients observed
Marker | AUC 95%CI | Cut-off | Sensitivity 95%CI | Specificity 95%CI | PPV 95%CI | NPV 95%CI | LR + 95%CI |
|---|---|---|---|---|---|---|---|
PSP Median value | 0.814 (0.584–1.000) | 421 | 0.833 (0.359, 0.996) | 0.853 (0.689, 0.950) | 0.500 (0.187, 0.813) | 0.967 (0.828, 0.999) | 5.667 (2.339, 13.731) |
PCR Median value | 0.657 (0.355–0.958) | 15.1 | 0.500 (0.118, 0.882) | 0.882 (0.725, 0.967) | 0.429 (0.099, 0.816) | 0.909 (0.757, 0.981) | 4.250 (1.255, 14.391) |
PCT Median value | 0.814 (0.633–0.994) | 14.4 | 0.667 (0.223, 0.957) | 0.853 (0.689, 0.950) | 0.444 (0.137, 0.788) | 0.935 (0.786, 0.992) | 4.533 (1.688, 12.171) |