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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: Chromosome 1p36 candidate gene ZNF436 predicts the prognosis of neuroblastoma: a bioinformatic analysis

Fig. 2

Expressions and prognosis of 1p candidate genes in neuroblastoma. (a) The common differentially expressed genes in 1p deleted neuroblastoma in E-MTAB-1781, GSE13136 and GSE73517 datasets. (b) Enriched transcription factors using the differentially expressed genes in 1p deleted neuroblastoma in E-MTAB-1781 dataset. (c) Expressions of BCAR3, CLSTN1, CTNNBIP1, DNAJC8, HMGCL, NMNAT1, PANK4, PHF13, STX12, UBE2J2 and ZNF436 in neuroblastoma with 1p deletion or without 1p deletion in E-MTAB-1781, GSE13136 and GSE73517 datasets. (d) Forest plots showed the associations of BCAR3, CLSTN1, CTNNBIP1, DNAJC8, HMGCL, NMNAT1, PANK4, PHF13, STX12, UBE2J2 and ZNF436 with the neuroblastoma overall survival in E-MTAB-1781, TARGET, GSE16476, GSE62564 and GSE85047 datasets. HR and P values were determined by univariate cox regression analysis

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