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Table 1 Demographic data and clinical features of AKI associated MIS-C, related COVID-19

From: A retrospective analysis of acute kidney injury in children with post-COVID-19 multisystem inflammatory syndrome: insights into promising outcomes

 

AKI affecting previously normal kidney (n = 31)

AKI on top of chronic renal impairment (n = 11)

P-value

Age (year) a

7.5 (0.75–17)

9 (5–14)

0.464

Gender b (Male/female)

19 (61.3%)/12 (38.7%)

6 (54.5%)/ 5 (45.5%)

0.695

Weight (kg) a

23 (7.3–71)

22.5 (13–39)

0.308

Height (cm) c

121.1 ± 31.5

123.5 ± 25.9

0.818

BMI (kg/m2) c

18.8 ± 3.8

14.7 ± 1.5

0.002

Presenting features b

 Fever

27 (87.1%)

9 (81.8%)

0.667

 Dyspnoea

25 (80.6%)

11 (100%)

0.115

 GIT symptoms

17 (54.8%)

6 (54.5%)

0.987

 Rash

3 (9.7%)

0

0.284

MIS-C associating AKI b

 Cardiac

11 (35.5%)

2 (18.2%)

0.286

 Respiratory

25 (80.6%)

11 (100%)

0.115

 Gastro-intestinal

9 (29%)

0

0.044

 Hematologic

23 (74.2%)

7 (63.6%)

0.505

 Neurologic

10 (32.3%)

0

0.031

 Dermatologic

3 (9.7%)

0

0.284

 Vasopressors use b

5 (16.1%)

1 (9.1%)

0.567

 Oxygen therapy b

15 (48.4%)

9 (81.8%)

0.054

 Invasive Mechanical Ventilation b

13 (41.9%)

2 (18.2%)

0.158

 Duration of Mechanical Ventilation c

7.3 ± 3.3

8 ± 1.4

0.785

 Duration of PICU stay (days)c

(n = 21). 9.9 \(\pm\) 5.2

(n = 4). 8.5 \(\pm\) 3.1

0.624

 Duration of hospital stay (days)c

23.6 \(\pm\) 12.8

13.5 \(\pm\) 9.3

0.021

  1. AKI Acute kidney injury, MIS-C Multi system inflammatory syndrome in children, PICU Paediatric intensive care unit, BMI Body mass index, GIT Gastrointestinal tract. Data presented as median (minimum–maximum) a, number (percent) b or mean ± SD c and analysed by Mann–Whitney test a, Chi-Square test b, Student t-test c; respectively