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Table 2 Clinical features of AKI patients associated with MIS-C, related COVID

From: A retrospective analysis of acute kidney injury in children with post-COVID-19 multisystem inflammatory syndrome: insights into promising outcomes

 

AKI stage 1 (n = 8)

AKI stage 2 (n = 7)

AKI stage 3 (n = 16)

P-value

Age (year) a

11 (0.75–15)

9.5 (4–17)

7.1 (1–15.3)

0.893

Gender b Male/Female

4 (50%)/4 (50%)

5 (71.4%)/ 2 (28.6%)

10 (62.5%)/ 6 (37.5%)

0.690

Weight (kg) a

28.5 (7.3–63)

27 (15–57)

23 (9–71)

0.833

Height (cm) c

124.5 ± 38.6

117.7 ± 24.6

120.9 ± 32.1

0.921

BMI (kg/m2) c

17.5 ± 4.5

17.8 ± 2.1

19.8 ± 4

0.323

Co-morbid diseases b

1 (12.5%)

1 (14.3%)

7 (43.8%)

0.175

Presenting features b

 Fever

8 (100%)

7 (100%)

12 (75%)

0.116

 Dyspnoea

8 (100%)

7 (100%)

10 (62.5%)

0.031

 GIT symptoms

4 (50%)

3 (42.9%)

10 (62.5%)

0.650

 Rash

0

0

3 (18.8%)

0.211

System affection associating AKI b

 Cardiac

4

3

4

0.434

 Respiratory

8

7

10

0.031

 Gastro-intestinal

2

3

4

0.657

 Hematologic

6

5

12

0.982

 Neurologic

0

3

7

0.077

 Dermatologic

0

0

3

0.211

 Vasopressors use b

1 (12.5%)

2 (28.6%)

2 (12.5%)

0.596

 Oxygen therapy b

5 (62.5%)

5 (71.4%)

5 (31.3%)

0.135

 Invasive Mechanical Ventilation b

3 (37.5%)

2 (28.6%)

8 (50%)

0.605

 Duration of Mechanical Ventilation(days) c

6.7 ± 4.7

8 ± 1.4

7.4 ± 3.5

0.921

  1. AKI Acute kidney injury, MIS-C Multi system inflammatory syndrome in children, PICU Paediatric intensive care unit, BMI Body mass index, GIT Gastrointestinal tract. Data expressed as median (minimum–maximum) a, number (percent) b or mean ± SD c and analysed by Kruskal–Wallis test a, Chi-Square test b, One-Way ANOVA c; respectively. AKI Acute kidney injury, BMI Body mass index