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Table 2 Laboratory findings and pituitary volume at the diagnosis of PH and AAT

From: Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia

Patients

TSH, mUI/ml

(nv 0.27–4.2)

FT4, pmol/l

(nv 12–22)

TPOAb, IU/ml

(nv 0–34)

TGAb, IU/ml

(nv 0-115)

IGF-1, ng/ml

PRL,

uUI/ml

(nv 86–496)

E2,

pg/ml

(pv < 12)

TEST,

ng/dl

(pv < 20)

Pituitary

Volume, mm3

Patient 1

236.6

3.2

3486

200

53.6

214

13

NA

650

Patient 2

319

2.79

4580

289

88.5

497

5

NA

648,9

Patient 3

1214

1.03

597

1805

73.1

999

12.4

NA

514,8

Patient 4

962

5.5

1185.8

554.8

112

659.5

NA

NA

1830

Patient 5

1000

5.5

88.8

15.5

120.3

723.4

NA

NA

1965

Patient 6

1000

1.93

187.6

36.8

123.3

1362

NA

NA

1419,6

Patient 7

359.5

6.17

383.6

416.9

93.6

434

NA

NA

532,48

Patient 8

1648

3

1020

2040

NA

NA

NA

NA

1123

Patient 9

1113

4.3

1020

2040

55.8

838.2

20

NA

1514

Patient 10

324

0.5

98

31

201

255

NA

25

504

Patient 11

750

3.9

168

391

NA

485.8

16.4

418

3528

Patient 12

1016

4

296.4

NA

76.8

835.8

NA

NA

770

  1. AAT = Atrophic autoimmune thyroiditis; PH = pituitary hyperplasia; TSH = thyroid stimulating hormone; FT4 = free thyroxine; TPOAb = thyroid peroxidase antibodies; TGAb = thyroglobulin antibodies; IGF-1 = insulin growth factor-1; PRL = prolactin; E2 = estradiol; TEST = testosterone; nv = normal values; NA = not available, pv = prepubertal values