Table 5 Clinical features, laboratory findings and pituitary volume at 12-month assessment
From: Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia
Patients | Height, cm (SDS) | Pubertal Stage (B/G-P) | Clinical findings | TSH, mUI/ml | FT4, pmol/l | TPOAb, IU/ml | TGAb, IU/ml | IGF-1, ng/ml | PRL, uUI/ml | Pituitary volume, mm3 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient 1 | 139.8 (-3.25) | B4P4 | Dry and thickened skin | 0.2 | 17.25 | NA | NA | NA | NA | NA | ||
Patient 2 | 136.6 (-1.83) | B3P3 | No symptoms | 5.62 | 13.6 | 223 | 279 | 230 | 134 | 287.0 | ||
Patient 3 | 134.4 (-0.06) | B2P2 | No symptoms | 1.23 | 16.1 | 374 | 1114 | 445 | 157 | 160.3 | ||
Patient 4 | 145.1 (-1.1) | G2P2 | No symptoms | 3.1 | 11.32 | 191.7 | 72.1 | 125 | NA | NA | ||
Patient 5 | 169.1 (-0.39) | G4P4 | No symptoms | 1.4 | 15.05 | 48.5 | 19.2 | 120.3 | NA | 171.6 | ||
Patient 6 | 129.5 (-1) | B1P1 | No symptoms | 1.16 | 12.61 | 39.3 | 17.9 | 197 | 121.27 | NA | ||
Patient 7 | 129.1 (-1.06) | B1P1 | No symptoms | 2.38 | 13.77 | 219 | 115 | 183.2 | 57.44 | NA | ||
Patient 8 | NA | NA | No symptoms | 2.25 | 15.0 | NA | NA | NA | NA | 185.00 | ||
Patient 12 | 144.2 (-1.87) | G4P3 | No symptoms | 4.86 | 13.9 | NA | NA | NA | 173.6 | 270.4 | ||