Fig. 8

Flow chart of suggested genetic testing strategy. Significant clinical manifestations*: Positive family history, early-onset ages, abnormal renal biopsy, special extra-renal manifestations, combined with glomerular hematuria or/and renal insufficiency or/and hypocomplementemia. High suspicion of genetic diagnosis*: SRNS children with poor treatment effect or/and rapid deterioration in a short time or/and other clinical features our article did not mention