Table 1 The clinical and renal pathological features of 4 patients at diagnosis

Age at onset (years)

1

5.3

10.5

3.5

Age at diagnosis (years)

1

5.3

10.5

3.5

Gender

Female

Female

Female

Female

Renal manifestation

 Edema

Y

Y

N

Y

 Hypertension

Y

Y

Y

Y

 oliguria

Y

Y

Y

Y

 Extra-renal manifestation

N

N

HF

UD, ID

 Renal pathology

FSGS

FSGS

NA

FSGS

 Hematuria

2+

2+

-

2+

 Proteinuria

3+

3+

4+

4+

 24hUP (mg/24h)

4000

2245.6

NA

2828.3

 Serum albumin(g/L)

20.9

28.6

31.6

20

 Serum creatinine at onset (mg/dl)

0.58

0.4

6.26

0.34

 eGFR at onset (ml/min/1.73m²)

57

110

9.6

114

 eGFR at last follow-up (ml/min/1.73m²)

9.0

5.0

9.6

42

 Age of ESKD (years)

1.5

9

10.5

NA