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  1. Transient hypothyroxinemia of prematurity (THOP) is defined as a low level of circulating thyroxine (T4), despite low or normal thyroid-stimulating hormone (TSH) levels. Aims: We aimed to evaluate the incidenc...

    Authors: Aslan Yilmaz, Yavuz Ozer, Nesrin Kaya, Aydilek Dagdeviren Cakir, Hazal Cansu Culpan, Yildiz Perk, Mehmet Vural and Olcay Evliyaoglu
    Citation: Italian Journal of Pediatrics 2023 49:105

    The Correction to this article has been published in Italian Journal of Pediatrics 2023 49:130

  2. The Order of Physicians and Dentists of the Province of Rome aims at focusing on the satisfaction of healthcare personnel as an essential factor for the quality of medical care in the health sector. The aim of...

    Authors: Martina Sapienza, Giuseppe Furia, Domenico Paolo La Regina, Valentina Grimaldi, Maria Grazia Tarsitano, Cristina Patrizi, Giovanni Capelli and Gianfranco Damiani
    Citation: Italian Journal of Pediatrics 2023 49:104
  3. Over 16 million children have been detected positive for the coronavirus disease 2019 (COVID-19) in the United States since the outbreak of the pandemic. In general, children infected with severe acute respira...

    Authors: Jingzhi Wen, Xiaoan Du, Adan Li, Shungeng Zhang, Shengyun Shen, Ziteng Zhang, Liyuan Yang, Changqing Sun, Jianing Li and Shiheng Zhu
    Citation: Italian Journal of Pediatrics 2023 49:103
  4. In this study, we intend to retrospectively analyze the clinical data of postoperative neuroblastoma children, including the results of follow-up examinations and laboratory tests, to explore the clinical valu...

    Authors: Jinmin Li, Zilong Qi, Mo Chen, Jiachen Wang and Xiangyang Liu
    Citation: Italian Journal of Pediatrics 2023 49:102
  5. Ligneous Conjunctivitis (LC) is the most common clinical manifestation of Type I Plasminogen deficiency (T1PD; OMIM# 217090), and it is characterized by the formation of pseudomembranes (due to deposition of f...

    Authors: Filippo Maria Panfili, Paola Valente, Andrea Ficari, Fabiana Cortellessa, Davide Vecchio, Michaela Veronika Gonfiantini, Paola Sabrina Buonuomo, Giovanna Stefania Colafati, Emanuele Agolini, Maria Bartuli, Alessandra Claudia Modugno and Marina Macchiaiolo
    Citation: Italian Journal of Pediatrics 2023 49:101
  6. Diagnosing central precocious puberty (CPP) requires an integrated approach based on clinical, biochemical and instrumental data. The diagnostic gold standard is represented by GnRH (gonadotropin-releasing hor...

    Authors: Ilaria Brambilla, Carmen Guarracino, Carmelo Pistone, Catherine Klersy, Amelia Licari, Gian Luigi Marseglia and Enrico Tondina
    Citation: Italian Journal of Pediatrics 2023 49:100
  7. Neurodevelopmental disorders have a multifactorial etiology, since biological, genetic, psychosocial and environmental risk factors are involved. Recent studies have been linking neurodevelopmental disorders a...

    Authors: Andrea Querzani, Fabio Sirchia, Gianluca Rustioni, Alessandra Rossi, Alessandro Orsini, Gian Luigi Marseglia, Salvatore Savasta, Luisa Chiapparini and Thomas Foiadelli
    Citation: Italian Journal of Pediatrics 2023 49:99
  8. Shwachman-Diamond syndrome (SDS) is a rare congenital disorder caused by mutations in the SBDS gene and characterized by exocrine pancreatic deficiency, hematologic dysfunction, and skeletal growth failure. Al...

    Authors: Lusine V. Navasardyan, Ingrid Furlan, Stephanie Brandt, Ansgar Schulz, Martin Wabitsch and Christian Denzer
    Citation: Italian Journal of Pediatrics 2023 49:98
  9. Basic motor competencies (BMC) play a vital role in child development and are a primary focus of physical education. However, there is a lack of research on BMC in preschool-aged children, making this study pa...

    Authors: Gaizka Legarra-Gorgoñon, Yesenia García-Alonso, Robinson Ramírez-Vélez, Blanca Erice-Echegaray, Mikel Izquierdo and Alicia M. Alonso-Martínez
    Citation: Italian Journal of Pediatrics 2023 49:97
  10. Fusobacterium necrophorum is an anaerobic, gram-negative, non-motile, filamentous, non-spore forming bacillus found in the oral cavity, gastrointestinal tract, and female genital tract, responsible of a rare dise...

    Authors: Laura Venditto, Giuliana Ferrante, Anna Caccin, Giulia Franchini, Marco Zaffanello, Laura Tenero, Michele Piazza, Stefano Di Gioia, Giorgio Piacentini and Angelo Pietrobelli
    Citation: Italian Journal of Pediatrics 2023 49:96
  11. Chronic Granulomatous Disease (CGD) is a primary immunodeficiency that causes susceptibility to recurrent fungal and bacterial infections. The CYBB gene encodes gp91phox component of the Phagocytic Nicotinamide a...

    Authors: Irum Gul, Taj Ali Khan, Noor ul Akbar, Naila Gul, Rehman Ali and Shahid Niaz Khan
    Citation: Italian Journal of Pediatrics 2023 49:95
  12. Primary adrenal insufficiency (PAI) in childhood is a life-threatening disease most commonly due to impaired steroidogenesis. Differently from adulthood, autoimmune adrenalitis is a rare condition amongst PAI’...

    Authors: Marta Arrigoni, Paolo Cavarzere, Lara Nicolussi Principe, Rossella Gaudino and Franco Antoniazzi
    Citation: Italian Journal of Pediatrics 2023 49:94
  13. Multiple immunopathological responses to viruses are observed in infectious mononucleosis (IM), a manifestation of primary infection with Epstein-Barr virus (EBV). Protective effects of the negative immunoregu...

    Authors: Mingsheng Zhao, Li Ma, Huihui Jiang, Yufeng Gu, Xin Yang, Riming Liu, Chengming Sun and Yulan Li
    Citation: Italian Journal of Pediatrics 2023 49:93
  14. Tracheal compression (TC) due to vascular anomalies is an uncommon, but potentially serious cause of chronic respiratory disease in childhood. Vascular slings are congenital malformations resulting from abnorm...

    Authors: Adele Corcione, Melissa Borrelli, Leonardo Radice, Oliviero Sacco, Michele Torre, Francesco Santoro, Gaetano Palma, Eleonora Acampora, Francesca Cillo, Pietro Salvati, Angelo Florio and Francesca Santamaria
    Citation: Italian Journal of Pediatrics 2023 49:92
  15. We describe the first school-located influenza vaccination campaign with quadrivalent live-attenuated influenza vaccine (LAIV) among pre-school children in Italy, coupled with an innovative school-centred infl...

    Authors: Antonella Amendola, Elisa Borghi, Silvia Bianchi, Maria Gori, Clara Fappani, Lucia Barcellini, Federica Forlanini, Nicolò Garancini, Chiara Nava, Alessandra Mari, Anna Sala, Chiara Gasparini, Emerenziana Ottaviano, Daniela Colzani, Elia Mario Biganzoli, Elisabetta Tanzi…
    Citation: Italian Journal of Pediatrics 2023 49:91
  16. Studies on Multisystem Inflammatory Syndrome in Children (MIS-C) and Kawasaki Disease (KD) have yielded inconsistent results and are lacking in Asian and African countries. This study aimed to compare the labo...

    Authors: Saghar Mehrban, Fatemeh Tahghighi, Ehsan Aghaei Moghadam and Vahid Ziaee
    Citation: Italian Journal of Pediatrics 2023 49:90
  17. Down syndrome is a genetic disorder caused by trisomy of chromosome 21 and characterized by an increased risk of multiorgan involvement. In Down syndrome children, functional constipation and lower urinary tra...

    Authors: Roberta Onesimo, Cristiana Agazzi, Luca Massimi, Valentina Giorgio, Chiara Leoni, Giuseppe Zampino and Claudia Rendeli
    Citation: Italian Journal of Pediatrics 2023 49:89
  18. In pediatric age, Group A Streptococcus (GAS) is responsible for a wide spectrum of clinical manifestations, from mild localized infections to life-threatening invasive diseases. In December 2022, the World He...

    Authors: Nicolò Garancini, Giulia Ricci, Michele Ghezzi, Paola Tommasi, Fiammetta Zunica, Anna Mandelli, Elena Zoia, Enza D’Auria and Gian Vincenzo Zuccotti
    Citation: Italian Journal of Pediatrics 2023 49:88
  19. In recent years screening of type 1 diabetes (T1D) in both at risk children and general population has been widely discussed with the aim of increasing awareness of the importance to early detect (and possibly...

    Authors: Valentino Cherubini and Francesco Chiarelli
    Citation: Italian Journal of Pediatrics 2023 49:87
  20. Sandplay therapy is a psychotherapeutic technique, based on the psychoanalytic theory of the unconscious. Nearly a century after it was developed, sandplay can now be applied for the initial diagnosis tools fo...

    Authors: Ying Ge, Jun Yu Huo, Hai Bo Yang, Jay L. Wenger, Jing Yi Yuan and Xiao Jie Sun
    Citation: Italian Journal of Pediatrics 2023 49:86
  21. Cornelia de Lange syndrome is a rare genetic disease with otolaryngological involvement. The classic phenotype is characterized by distinctive facial features, intellectual disability, growth delay, hirsutism,...

    Authors: Roberta Onesimo, Rita De Santis, Chiara Leoni, Mario Rigante, Marco Piastra, Elisabetta Sforza, Angelo Selicorni and Giuseppe Zampino
    Citation: Italian Journal of Pediatrics 2023 49:85
  22. Congenital dyserythropoietic anemias (CDAs) are a very rare and heterogeneous group of disorders characterized by ineffective erythropoiesis. CDA II is caused by mutations in the SEC23B gene. The most common muta...

    Authors: Arati Nandan Saptarshi, Rashmi K. Dongerdiye, Tejashree Anil More and Prabhakar S. Kedar
    Citation: Italian Journal of Pediatrics 2023 49:84
  23. Duchenne muscular dystrophy (DMD) is a rare hereditary muscular disease. The role of eosinophils in DMD has not been clarified. This study aims to evaluate the association between peripheral blood eosinophil c...

    Authors: Zhi Jiang, Hongmei Liao, Liwen Wu, Wenjing Hu, Liming Yang, Bo Chen, Zeshu Ning, Jingwen Tang, Rong Xu, Mei Chen, Feng Guo and Shulei Liu
    Citation: Italian Journal of Pediatrics 2023 49:83
  24. During the COVID-19 pandemic, accesses to pediatric health care services decreased, as well as the consumption of traditional drugs, while the median cost per patient at the emergency department slightly incre...

    Authors: Roberto Franceschi, Evelina Maines, Angelamaria Petrone, Simone Bilato, Ilaria Trentini, Lorenzo Di Spazio, Luca Leonardi, Massimo Soffiati and Andrea Francesconi
    Citation: Italian Journal of Pediatrics 2023 49:82
  25. Robust routine immunization schedules for pertussis-containing vaccines have been applied for years, but pertussis outbreaks remain a worldwide problem. This study aimed to investigate the association between ...

    Authors: Yuning Wang, Naiyang Shi, Qiang Wang, Liuqing Yang, Tingting Cui and Hui Jin
    Citation: Italian Journal of Pediatrics 2023 49:81
  26. To examine the clinical impact of bronchoscope alveolar lavage (BAL) combination with budesonide, ambroxol + budesonide, or acetylcysteine + budesonide in the treatment of refractory Mycoplasma pneumoniae pneu...

    Authors: Yanli Wang, Kai Liu, Chuangui Chen and Chengyun Zhang
    Citation: Italian Journal of Pediatrics 2023 49:80
  27. In recent decades some studies described the frequent co-occurrence of celiac disease autoimmunity and overt celiac disease in patients with autism. Therefore, it was suggested that celiac disease could play a...

    Authors: Stefania Zambrano, Barbara Parma, Valeria Morabito, Silvia Borini, Roberta Romaniello, Massimo Molteni, Elisa Mani and Angelo Selicorni
    Citation: Italian Journal of Pediatrics 2023 49:79
  28. Intravenous immunoglobulin (IVIG) has been the mainstay of treatment for Kawasaki disease (KD) over the past decades. However, 10–20% of KD patients are resistant to IVIG treatment which puts those patients at...

    Authors: Rui Zhang, Shuping Shuai, Hongxi Zhang, Jianghui Cai, Na Cui, Mi Tang, Shasha Xing, Yu Gao, Xia Liu and Xiao Yang
    Citation: Italian Journal of Pediatrics 2023 49:78
  29. Familial hypercholesterolaemia (FH) is a frequent genetic disorder characterised by high plasma levels of total and LDL-cholesterol and premature atherosclerosis. If left untreated, affected subjects have a hi...

    Authors: Maria Elena Capra, Giacomo Biasucci, Elisa Crivellaro, Giuseppe Banderali and Cristina Pederiva
    Citation: Italian Journal of Pediatrics 2023 49:77
  30. The prevalence of children with medical complexity is increasing, therefore drug formulations must be updated in accordance with their needs. Furthermore, a different drug formulation may be also needed for pa...

    Authors: Francesca Burlo, Davide Zanon, Paola Minghetti, Valentina Taucar, Giulia Benericetti, Giada Bennati, Egidio Barbi and Lucia De Zen
    Citation: Italian Journal of Pediatrics 2023 49:76
  31. Malnutrition including undernutrition, overnutrition, and micronutrient deficiencies are considerable problems worldwide, with variable burdens among different communities. Its complications include physical a...

    Authors: Hanan Mina Fouad, Aly Yousef, Ahmed Afifi, Ahmed A. Ghandour, Amira Elshahawy, Ayman Elkhawass, Hazem Hawees, Eman Shaheen, Mohamed Alaaeldin, Mostafa Kamal, Samah Bastawy, Samah Rabie, Farah Wissa and Sherine Shalaby
    Citation: Italian Journal of Pediatrics 2023 49:75
  32. Drowning is the third leading cause of injury death in the pediatric population worldwide, with incidence peaking among those aged 1–4 years and again in adolescence.

    Authors: Francesco Pellegrino, Irene Raffaldi, Roberta Rossi, Barbara De Vito, Manuela Pagano, Davide Garelli and Claudia Bondone
    Citation: Italian Journal of Pediatrics 2023 49:74
  33. Pyomyositis is an unusual bacterial infection but potential severe in children. Staphylococcus Aureus is the main caused of this disease (70–90%), following by Streptococcus Pyogenes (4–16%). Streptococcus Pne...

    Authors: Luca Barchi, Michele Fastiggi, Ilaria Bassoli, Federico Bonvicini, Monica Silvotti, Lorenzo Iughetti and Alessandro De Fanti
    Citation: Italian Journal of Pediatrics 2023 49:73
  34. It is known that human milk fortifiers (HMF) increases osmolality of human milk (HM) but some aspects of fortification have not been deeply investigated. Our aim was to evaluate the effect of fortification on ...

    Authors: Serena Elia, Martina Ciarcià, Nicoletta Cini, Francesca Luceri, Mauro Leucio Mattei, Francesca Miselli, Silvia Perugi, Alessandra Fanelli and Carlo Dani
    Citation: Italian Journal of Pediatrics 2023 49:72
  35. Gender dysphoria is a clinical condition characterized by significant distress due to the discordance between biological sex and gender identity. Currently, gender dysphoria is also found more frequently in ch...

    Authors: Ginevra Micangeli, Giovanni Profeta, Fiorenza Colloridi, Federica Pirro, Francesca Tarani, Giampiero Ferraguti, Matteo Spaziani, Andrea M. Isidori, Michela Menghi, Marco Fiore and Luigi Tarani
    Citation: Italian Journal of Pediatrics 2023 49:71
  36. This Position Statement updates the different components of the therapy of obesity (lifestyle intervention, drugs, and surgery) in children and adolescents, previously reported in the consensus position statem...

    Authors: Claudio Maffeis, Francesca Olivieri, Giuliana Valerio, Elvira Verduci, Maria Rosaria Licenziati, Valeria Calcaterra, Gloria Pelizzo, Mariacarolina Salerno, Annamaria Staiano, Sergio Bernasconi, Raffaele Buganza, Antonino Crinò, Nicola Corciulo, Domenico Corica, Francesca Destro, Procolo Di Bonito…
    Citation: Italian Journal of Pediatrics 2023 49:69
  37. Sleep disorders refer to physiological and psychological states that cause adverse consequences due to the inability to fall asleep or poor sleep quality. The prevalence of sleep disorders varies greatly in di...

    Authors: Yongwei Gao, Peiru Xu, Maiming Aizetiguli, Shan Surong, Zhaoxuan Zhu and Jing Zhang
    Citation: Italian Journal of Pediatrics 2023 49:68
  38. To explore the impact of the transition from a traditional face-to-face course delivering essential contents in pediatric critical care to a hybrid format consisting of an online pre-course self-directed learn...

    Authors: Anna Zanin, Angela Aramburo Caragol, Luca Tortorolo, Michele Patui, Beatrice Pedrini, Joe Brierley, Bruce Lister and Paola Cogo
    Citation: Italian Journal of Pediatrics 2023 49:67
  39. Bronchiolitis is a major cause of hospitalization in infants, particularly in the first six months of life, with approximately 60–80% of admissions due to respiratory syncytial virus (RSV) infection. Currently...

    Authors: Maria Elisabetta Baldassarre, Daniela Loconsole, Francesca Centrone, Desiree Caselli, Baldassarre Martire, Lorenzo Quartulli, Angelo Acquafredda, Gabriele D’Amato, Gianfranco Maffei, Giuseppe Latorre, Anita Riganti, Michele Di Noia, Maria Chironna and Nicola Laforgia
    Citation: Italian Journal of Pediatrics 2023 49:66
  40. This narrative non-systematic review addresses the sex-specific differences observed both in prenatal period and, subsequently, in early childhood. Indeed, gender influences the type of birth and related compl...

    Authors: Claudio Migliori, Marta Braga, Virginia Siragusa, Maria Cristina Villa and Livio Luzi
    Citation: Italian Journal of Pediatrics 2023 49:65
  41. Spinal muscular atrophy (SMA) could be classified as 5q and non-5q, based on the chromosomal location of causative genes. A rare form of non-5q SMA is an autosomal-recessive condition called spinal muscular at...

    Authors: Ali Najafi, Behnoosh Tasharrofi, Farshid Zandsalimi, Maryam Rasulinezhad, Masood Ghahvechi Akbari, Gholamreza Zamani, Mahmoud Reza Ashrafi and Morteza Heidari
    Citation: Italian Journal of Pediatrics 2023 49:64
  42. In patients with adrenal insufficiency (AI), adrenal crisis (AC) represents a clinical emergency. Early recognition and prompt management of AC or AC-risk conditions in the Emergency Department (ED) can reduce...

    Authors: Enrica Abrigo, Jessica Munarin, Claudia Bondone, Gerdi Tuli, Emanuele Castagno, Luisa de Sanctis and Patrizia Matarazzo
    Citation: Italian Journal of Pediatrics 2023 49:63
  43. To investigate the efficacy and safety of endoscopic electrocoagulation haemostasis via a percutaneous transhepatic approach for the treatment of grade IV haemorrhagic cystitis (HC) after allogeneic haematopoi...

    Authors: Hai-chao Liu, Yun-bo Yang, Peng Zhang, Jia-xing Zhang, Zhi-sheng Pei, Bo-wen Chen, Gui-qian Liu and Hui Li
    Citation: Italian Journal of Pediatrics 2023 49:62
  44. Acute cerebellar ataxia (ACA) and acute cerebellitis represent disorders characterized by a para-infectious, post-infectious, or post-vaccination cerebellar inflammation. They are relatively common neurologic ...

    Authors: Nicola Adriano Monzani, Antonio Corsello, Claudia Tagliabue, Raffaella Pinzani, Eleonora Mauri, Carlo Agostoni, Gregorio Paolo Milani and Robertino Dilena
    Citation: Italian Journal of Pediatrics 2023 49:61
  45. Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD,...

    Authors: Wenyan Jiao, Li Wei, Fuyong Jiao, Dorina Pjetraj, Jianying Feng, Jvyan Wang, Carlo Catassi and Simona Gatti
    Citation: Italian Journal of Pediatrics 2023 49:60
  46. Diabetic ketoacidosis (DKA) is one of the most alarming concerns in the management of type 1 diabetes (T1D) in pediatric age. Prevalence of DKA at the onset of diabetes ranges from 30 to 40%. In selected cases...

    Authors: Stefano Passanisi, Giuseppina Salzano, Pietro Basile, Bruno Bombaci, Flavia Caime, Immacolata Rulli, Mariella Valenzise, Eloisa Gitto and Fortunato Lombardo
    Citation: Italian Journal of Pediatrics 2023 49:58
  47. Tacrolimus is the backbone drug in kidney transplantation. Single nucleotide polymorphism of Multidrug resistant 1 gene can affect tacrolimus metabolism consequently it can affect tacrolimus trough level and i...

    Authors: Mai S Korkor, Tarek el-desoky, Youssef M Mosaad, Doaa M. Salah and Ayman Hammad
    Citation: Italian Journal of Pediatrics 2023 49:57

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