Table 3 Biochemical parameters in serum of β-thalassemia major patients' groups and controls.

Cystatin-C (mg/L)

0.83 ± 0.05

1.26 ± 0.34

1.03 ± 0.26

Range

(0.80 - 0.90)

(0.85-2.00)

(0.82-2.12)

Significance

P < 0.0001

P < 0.022, * P < 0.001

Creatinine (mg/dL)

0.55 ± 0.08

0.75 ± 0.18

0.70 ± 0.21

Range

(0.50 -0.70)

(0.50-1.10)

(0.40-1.10)

Significance

P < 0.001

P < 0.008, *P < 0.262

eGFR _Schwartz (mL/min/1.73 m²)

119.08 ± 11.13

92.67 ± 25.16

93.73 ± 25.53

Range

(96.25-125.40)

(53.17-125.40)

(49.50-125.40)

Significance

P < 0.001

P < 0.001, *P < 0.852

≥90 mL/minute/1.73 m²

15 (100.00%)

14 (41.18%)

19 (54.29%)

< 90 mL/minute/1.73 m²

20 (58.82%)

16 (45.71%)

Uric acid (mg/dL)

3.81 ± 1.19

5.69 ± 1.69

5.30 ± 1.49

Range

(2.50-5.50)

(2.00-8.50)

(2.50-7.50)

Significance

P < 0.0001

P < 0.002, *P < 0.292

Calcium (mg/dL)

9.35 ± 1.11

9.10 ± 1.41

8.59 ± 1.86

Range

(8.01-10.95)

(6.09-11.10)

(5.35-12.37)

Significance

P < 0.121

P < 0.607, *P < 0.183

Inorganic phosphate (mg/dL)

3.32 ± 0.72

4.69 ± 0.87

4.50 ± 1.14

Range

(2.38-4.40)

(3.60-7.11)

(2.31-6.92)

Significance

P < 0.001

P < 0.001, *P < 0.412

Total antioxidant capacity (mmol/L)

0.43 ± 0.12

0.18 ± 0.10

0.23 ± 0.13

Range

(0.24-0.60)

(0.03-0.36)

(0.02-0.41)

Significance

P < 0.0001

P < 0.0001, * P < 0.048