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  1. To study whether the four locus gene model consisting of ADRB2 rs1042713, IL4 rs2243250, FCER1B rs569108 and L13 rs20541 can predict asthma of the Kazak children in Xinjiang, China.

    Authors: Shasha Bai, Jun Lu, Li Hua, Quanhua Liu, Mengxue Chen, Yutong Gu, Jianhua Zhang, Dongjun Ma and Yixiao Bao
    Citation: Italian Journal of Pediatrics 2023 49:162
  2. The European Union (EU) approved the placement on European market of insect-based novel foods. Those foods were defined safe for the consumption for all European population, including children.

    Authors: Lorenzo Norsa, Carlo Agostoni, Teresa Capriati, Angelo Campanozzi, Antonella Diamanti, Antonella Lezo, Paolo Gandullia, Maria Immacolata Spagnuolo and Claudio Romano
    Citation: Italian Journal of Pediatrics 2023 49:161
  3. Tourette Syndrome (TS) is a disorder in which the patient has a history of multiple motor and vocal tics. Depression and anxiety are common in these patients. The results of the studies show different prevalen...

    Authors: Parvin Abbasi, Sepideh Tanhaie and Mohsen Kazeminia
    Citation: Italian Journal of Pediatrics 2023 49:160
  4. Individuals with thiamine-responsive megaloblastic anemia (TRMA) mainly manifest macrocytic anemia, sensorineural deafness, ocular complications, and nonautoimmune diabetes. Macrocytic anemia and diabetes may ...

    Authors: Francesca Di Candia, Valentina Di Iorio, Nadia Tinto, Riccardo Bonfanti, Claudio Iovino, Francesco Maria Rosanio, Ludovica Fedi, Fernanda Iafusco, Francesca Arrigoni, Rita Malesci, Francesca Simonelli, Andrea Rigamonti, Adriana Franzese and Enza Mozzillo
    Citation: Italian Journal of Pediatrics 2023 49:158
  5. Tolosa-Hunt syndrome (THS) and recurrent painful ophthalmoplegic neuropathy (RPON) are rare diseases reported within the “Painful lesions of the cranial nerves” section of the International Classification of H...

    Authors: Daniele Frattini, Alessandro Iodice, Carlotta Spagnoli, Susanna Rizzi, Carlo Alberto Cesaroni, Michela Cappella and Carlo Fusco
    Citation: Italian Journal of Pediatrics 2023 49:157
  6. Erythropoietic protoporphyria is a rare disorder which represents an important health problem in children, causing painful photosensitivity. Little is known on the correlation between genetic profile and clini...

    Authors: Cristina Tumminelli, Francesca Burlo, Serena Pastore, Giovanni Maria Severini, Irene Berti, Stefano Marchini, Davide Zanon, Eleonora De Martino and Alberto Tommasini
    Citation: Italian Journal of Pediatrics 2023 49:156
  7. The pediatric genetic white matter disorders are characterized by a broad disease spectrum. Genetic testing is valuable in the diagnosis. However, there are few studies on the clinical and genetic spectrum of ...

    Authors: Liling Dong, Li Shang, Caiyan Liu, Chenhui Mao, Xinying Huang, Shanshan Chu, Bin Peng, Liying Cui and Jing Gao
    Citation: Italian Journal of Pediatrics 2023 49:155
  8. The social restrictions resulting from the COVID-19 pandemic had a great impact on the routine of children and adolescents, with important consequences such as sleep, eating, and psychological/psychiatric diso...

    Authors: Mariana Godoy-Leite, Fernanda Gabriela Colombo Drumond Santos, Eduardo Augusto Resende Penido, Kennad Alves Ribeiro, Luzia Maria dos Santos, Maria da Gloria Rodrigues-Machado and Bruno Almeida Rezende
    Citation: Italian Journal of Pediatrics 2023 49:154
  9. Complementary and alternative medicine (CAM) consist of a broad group of restorative resources often linked to existing local cultures and established health care systems and are also increasingly used in chil...

    Authors: Francesca Casini, Francesca Scaltrito, Maria Teresa Grimaldi, Tudor Lucian Pop, Valeria Calcaterra, Gian Vincenzo Zuccotti, Massimo Pettoello-Mantovani, Pietro Ferrara, Giovanni Corsello and Valentina Fabiano
    Citation: Italian Journal of Pediatrics 2023 49:152
  10. Congenital clubfoot is a fairly common and severe congenital malformation, most often of idiopathic origin. A smaller percentage of cases is related to chromosomal abnormalities and genetic syndromes. It is es...

    Authors: Raffaella Panza, Federica Albano, Alberto Casto, Cosimo Del Vecchio, Nicola Laforgia and Daniela Dibello
    Citation: Italian Journal of Pediatrics 2023 49:151
  11. The present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were referred to the ADHD reference centre of Scientific Institute IRCCS E. Mede...

    Authors: Simone Amendola, Isabella Fanizza, Sara Scoditti, Marta De Rinaldis and Antonio Trabacca
    Citation: Italian Journal of Pediatrics 2023 49:150
  12. The purpose of this study was to summarize the early clinical results and surgical experience of repairing the right common carotid artery and the right internal jugular vein after ECMO treatment in neonates.

    Authors: Qi-Liang Zhang, Xiu-Hua Chen, Si-Jia Zhou, Yi-Rong Zheng, Hua Cao and Qiang Chen
    Citation: Italian Journal of Pediatrics 2023 49:149
  13. The prevalence of food allergies (FA) has been steadily increasing over 2 to 3 decades, showing diverse symptoms and rising severity. These long-term outcomes affect children’s growth and development, possibly...

    Authors: Xiumei Yan, Jingbin Yan, Qiangwei Xiang, Huan Dai, Yinghui Wang, Lingjuan Fang, Kaiyu Huang and Weixi Zhang
    Citation: Italian Journal of Pediatrics 2023 49:148
  14. Ductal patency of preterm infants is potentially associated with long term morbidities related to either pulmonary overflow or systemic steal. When an interventional closure is needed, it can be achieved with ...

    Authors: Gaia Francescato, Daniela Doni, Giuseppe Annoni, Irma Capolupo, Elena Ciarmoli, Iuri Corsini, Italo Francesco Gatelli, Sabrina Salvadori, Alberto Testa and Gianfranco Butera
    Citation: Italian Journal of Pediatrics 2023 49:147
  15. Coronary status at one month after Kawasaki disease (KD) onset had a great significance. The present study aimed to establish a prediction model for coronary artery aneurysms (CAA) at one month in children wit...

    Authors: Yunjia Tang, Chuxin Ding, Qiuqin Xu, Wanping Zhou, Yiming Qin, Meihua Lu and Haitao Lv
    Citation: Italian Journal of Pediatrics 2023 49:146
  16. Human Parechovirus is a common cause of infection occurring especially during the first years of life. It may present with a broad spectrum of manifestations, ranging from a pauci-symptomatic infection to a se...

    Authors: Elena Bozzola, Sarah Barni, Chiara Barone, Carlo Federico Perno, Andrea Maggioni and Alberto Villani
    Citation: Italian Journal of Pediatrics 2023 49:144
  17. This study investigates the correlation between coagulation levels and the severity of Mycoplasma pneumoniae pneumonia (MPP) in children. In addition, the study analyses the predictive value of coagulation abnorm...

    Authors: Yong-tao Li, Ju Zhang, Meng-zhu Wang, Yu-Mei Ma, Ke Zhi, Fu-Li Dai and Shu-jun Li
    Citation: Italian Journal of Pediatrics 2023 49:143
  18. The hemodynamic status of newborns with intracranial arteriovenous shunts (AVSs) may be extremely complex. Mini-invasive hemodynamic monitoring through innovative techniques such as Near-Infrared Spectroscopy ...

    Authors: Francesca Landolfo, Paola Giliberti, Domenico Umberto De Rose, Flaminia Pugnaloni, Alessandra Santisi, Claudia Columbo, Ludovica Martini, Maria Paola Ronchetti, Luca Di Chiara, Alessandra Toscano, Carlo Gandolfo, Andrea Dotta and Irma Capolupo
    Citation: Italian Journal of Pediatrics 2023 49:141
  19. Periodontal disease and its bacteria can be responsible for pregnancy complications and transmission of periodontal bacteria from mother to newborn.

    Authors: Monica Russo, Maria Grazia Calevo, Gloria D’Alessandro, Matteo Tantari, Marco Migliorati, Ilaria Piccardo, Paola Polo Perucchin and Cesare Arioni
    Citation: Italian Journal of Pediatrics 2023 49:140
  20. Maternal diabetes might be related to a high risk of allergic disease in offspring. However, it remains unknown if maternal gestational diabetes mellitus (GDM) is also associated with a high incidence of child...

    Authors: Xufeng Huang, Zhengguo Huang, Jing Zhang and You Jiang
    Citation: Italian Journal of Pediatrics 2023 49:139
  21. Palpitations represent a common cause for consultation in the pediatric Emergency Department (ED). Unlike adults, palpitations in children are less frequently dependent from the heart, recognizing other causes.

    Authors: Angelica De Nigris, Mattia Arenella, Giangiacomo Di Nardo, Giovanni Maria Di Marco, Annunziata Mormile, Daria Lauretta, Caterina De Simone, Angela Pepe, Rosaria Cosimi, Rossella Vastarella, Antonietta Giannattasio, Giovanni Salomone, Silverio Perrotta, Speranza Cioffi, Pierluigi Marzuillo, Vincenzo Tipo…
    Citation: Italian Journal of Pediatrics 2023 49:137
  22. Retinopathy of prematurity (ROP) is typically treated with laser photocoagulation and/or intravitreal anti-vascular endothelial growth factor (anti-VEGF). To the best of our knowledge, most systematic reviews ...

    Authors: Jing Chen, Qingfei Hao, Jing Zhang, Yanna Du, Haoming Chen and Xiuyong Cheng
    Citation: Italian Journal of Pediatrics 2023 49:136
  23. Children tend to have milder forms of COVID-19 than adults, however post-acute complications have been observed also in the paediatric population. In this study, we compared COVID-19-related outcomes and long-...

    Authors: Chiara Rosazza, Laura Alagna, Alessandra Bandera, Arianna Biffi, Fabiana Ciciriello, Andrea Gramegna, Vincenzina Lucidi, Paola Giovanna Marchisio, Paola Medino, Antonio Muscatiello, Sara Uceda Renteria and Carla Colombo
    Citation: Italian Journal of Pediatrics 2023 49:135
  24. Pancreatic Stone Protein (PSP) is one of the most promising diagnostic and prognostic markers. The aim of the study was to assess the accuracy of PSP, compared to C-Reactive Protein (CRP), and Procalcitonin (P...

    Authors: Gabriella Bottari, Mariangela Caruso, Emanuel Paionni, Maia De Luca, Lorenza Romani, Mara Pisani, Annalisa Grandin, Livia Gargiullo, Giorgio Zampini, Chiara Gagliardi, Danilo Alunni Fegatelli, Annarita Vestri, Laura Lancella, Ottavia Porzio, Andrea Onetti Muda, Alberto Villani…
    Citation: Italian Journal of Pediatrics 2023 49:134
  25. Extubation failure (EF) is a significant concern in mechanically ventilated newborns, and predicting its occurrence is an ongoing area of research. To investigate the predictors of EF in newborns undergoing pl...

    Authors: Maoling Fu, Zhenjing Hu, Genzhen Yu, Ying Luo, Xiaoju Xiong, Qiaoyue Yang, Wenshuai Song, Yaqi Yu and Ting Yang
    Citation: Italian Journal of Pediatrics 2023 49:133
  26. Neuroblastoma is the most frequent extracranial solid tumor occurring in childhood, representing approximately 28% of all cancers diagnosed in infants. Signs and symptoms of neuroblastoma vary with the site of...

    Authors: Carolina Carraro, Marco Rabusin, Flora Maria Murru, Lydie Ammar, Egidio Barbi, Alessandro Amaddeo and Giorgio Cozzi
    Citation: Italian Journal of Pediatrics 2023 49:132
  27. Antibiotic overuse in children is a significant public health concern, as it can lead to the emergence and spread of antibiotic-resistant bacteria. Although respiratory infections account for most antibiotic p...

    Authors: Marina Picca, Romeo Carrozzo, Gregorio Paolo Milani, Antonio Corsello, Marina Macchi, Roberto Buzzetti, Paola Marchisio and Chiara Mameli
    Citation: Italian Journal of Pediatrics 2023 49:131
  28. Authors: Aslan Yilmaz, Yavuz Ozer, Nesrin Kaya, Aydilek Dagdeviren Cakir, Hazal Cansu Culpan, Yildiz Perk, Mehmet Vural and Olcay Evliyaoglu
    Citation: Italian Journal of Pediatrics 2023 49:130

    The original article was published in Italian Journal of Pediatrics 2023 49:105

  29. Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ...

    Authors: Sheng-Hui Tuan, Jin-Hui Chung, Guan-Bo Chen, Shu-Fen Sun, I-Hsiu Liou, Chien-Hui Li and Yi-Ju Tsai
    Citation: Italian Journal of Pediatrics 2023 49:129
  30. COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management...

    Authors: Elena Bozzola, Carlo Caffarelli, Francesca Santamaria and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:128
  31. Beckwith-Wiedemann syndrome (BWS, OMIM #130,650) is a pediatric overgrowth disorder involving a predisposition to tumor development. Although the clinical management of affected patients is well established, i...

    Authors: Pierandrea Elefante, Beatrice Spedicati, Flavio Faletra, Laura Pignata, Flavia Cerrato, Andrea Riccio, Egidio Barbi, Luigi Memo and Laura Travan
    Citation: Italian Journal of Pediatrics 2023 49:127
  32. Early identification of intravenous immunoglobulin (IVIG) resistance contributes to better management of Kawasaki disease (KD). This study aims to establish an effective prediction model for IVIG resistance in...

    Authors: Junjie Wang, Xiaohui Huang and Donghao Guo
    Citation: Italian Journal of Pediatrics 2023 49:126
  33. There are relatively few studies investigating C-C motif chemokine ligand 2 (CCL2) level in bronchoalveolar lavage fluid (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP), and the relationship betw...

    Authors: Jiangwei Zhu, Xue Liu, Xiaowen Zhan, Mengzhu Wang, Yuling Zhang, Li Na and Shujun Li
    Citation: Italian Journal of Pediatrics 2023 49:125
  34. Tumors are rare in neonatal age. Congenital mesoblastic nephroma (CMN) is a usually benign renal tumor observed at birth, or in the first months of life. It may also be identified prenatally and associated wit...

    Authors: Gregorio Serra, Marcello Cimador, Mario Giuffrè, Vincenzo Insinga, Claudio Montante, Marco Pensabene, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:124
  35. Acute viral bronchiolitis is the most common cause of hospitalization in children under 12 months of age. The variable clinical presentation and the potential for sudden deterioration of the clinical condition...

    Authors: Federica Porcaro, Renato Cutrera, Anna Chiara Vittucci and Alberto Villani
    Citation: Italian Journal of Pediatrics 2023 49:123
  36. Headache is one of the most common pain syndromes in the paediatric population. Headaches are classified as primary (migraine, tension-type headaches, trigeminal autonomic cephalalgia and other primary headach...

    Authors: Léa Lenglart, Cécile Monteil, Eugenia Spreafico, Thomas Moulding and Luigi Titomanlio
    Citation: Italian Journal of Pediatrics 2023 49:122
  37. Influenza surveillance aims to determine onset, duration and intensity of the seasonal Influence-like Illness (ILI); data collection begins in the week 42 of a year and ends in the week 17 of the following yea...

    Authors: Stefania Ranno, Luana Coltella, Giulia Linardos, Velia Chiara Di Maio, Luna Colagrossi, Leonarda Gentile, Eugenia Galeno, Marta Luisa Ciofi degli Atti, Sebastian Cristaldi, Alberto Villani, Massimiliano Raponi, Carlo Federico Perno and Cristina Russo
    Citation: Italian Journal of Pediatrics 2023 49:121
  38. We investigated changes in microR-29c and microR-146a expression in the serum of children with Mycoplasma pneumoniae pneumonia, analysed their relationship with inflammatory factors and disease severity, and eval...

    Authors: Jingcai Wang, Chunyan Guo, Lixin Yang, Peng Sun and Xiaoqing Jing
    Citation: Italian Journal of Pediatrics 2023 49:119
  39. While existing research has explored changes in health behaviours among adults and adolescents due to the COVID-19 outbreak, the impact of quarantine on young children’s well-being is still less clear. Moreove...

    Authors: Marco Giustini, Ilaria Luzi, Angela Spinelli, Silvia Andreozzi, Mauro Bucciarelli, Marta Buoncristiano, Paola Nardone and Silvia Ciardullo
    Citation: Italian Journal of Pediatrics 2023 49:118
  40. Ophthalmia neonatorum is an acute conjunctivitis that occurs in newborns within the first month of life. The most serious infections are due to Chlamydia trachomatis and Neisseria gonorrhoeae, that may cause perm...

    Authors: Vito Mondì, Chryssoula Tzialla, Salvatore Aversa, Daniele Merazzi, Stefano Martinelli, Gabriella Araimo, Luca Massenzi, Giacomo Cavallaro, Luigi Gagliardi, Fiammetta Piersigilli, Mario Giuffrè, Simona Lozzi, Paolo Manzoni, Fabio Mosca, Irene Cetin, Vito Trojano…
    Citation: Italian Journal of Pediatrics 2023 49:117
  41. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with different initial symptoms and complex clinical manifestations. A 14-year-old female patient presented with persistent fever and severe h...

    Authors: Yanlin Li, Zhihua Si, Wei Zhao, Cong Xie, Xu Zhang, Ju Liu, Jinzhi Liu and Zhangyong Xia
    Citation: Italian Journal of Pediatrics 2023 49:116
  42. The last year saw intensive efforts to advance knowledge in pediatric medicine. This review highlights important publications that have been issued in the Italian Journal of Pediatrics in 2022. We have chosen ...

    Authors: Carlo Caffarelli, Francesca Santamaria, Ettore Piro, Simona Basilicata, Lorenzo D’Antonio, Bertrand Tchana, Sergio Bernasconi and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:115
  43. SARS-Cov2 infection began to spread worldwide since December 2019; on March 2020, the World Health Organization characterized its related disease, named COVID-19, as a pandemic. In Italy, to contain the spread...

    Authors: Paolo Cavarzere, Romina Pausilli, Lara Nicolussi Prinicpe, Rossella Gaudino, Alessandra Guzzo, Gaetano Cantalupo and Franco Antoniazzi
    Citation: Italian Journal of Pediatrics 2023 49:113

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