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  1. Content type: Case report

    Ring chromosome 6 (r(6)) is a rare disorder that mainly occurs as a ‘de novo’ event. Nonetheless, a wide phenotypic spectrum has been reported in r(6) cases, depending on breakpoints, size of involved region, ...

    Authors: Frenny Sheth, Thomas Liehr, Viraj Shah, Hillary Shah, Stuti Tewari, Dhaval Solanki, Sunil Trivedi and Jayesh Sheth

    Citation: Italian Journal of Pediatrics 2018 44:114

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  2. Content type: Research

    One of the most important vulnerabilities falling the efficacy of recombinant human growth hormone (r-hGH) treatment is low adherence especially in young patients. This study was planned to describe the correl...

    Authors: Maria Cristina Maggio, Beatrice Vergara, Paolo Porcelli and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2018 44:113

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  3. Content type: Research

    Viral respiratory infections may promote bacterial super-infection decreasing the host immune response efficiency. However, using a mice model we recently demonstrated that preventive treatment with the bacter...

    Authors: Giovanni A. Rossi, Wolfgang Bessler, Stefania Ballarini and Christian Pasquali

    Citation: Italian Journal of Pediatrics 2018 44:112

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  4. Content type: Case report

    Fetal supraventricular tachycardia (SVT), characterized by fetal heart rate between 220 and 260 bpm, is a rare but most commonly encountered fetal cardiac arrhythmia in pregnancy that may be associated with ad...

    Authors: Zanardo Vincenzo, Simbi Alphonse, Parotto Matteo, Severino Lorenzo, Carta Riccardo, Guerrini Pietro and Straface Gianluca

    Citation: Italian Journal of Pediatrics 2018 44:111

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  5. Content type: Case report

    Overgrowth syndromes are known as a heterogeneous group of conditions characterized by a generalized or segmental, symmetric or asymmetric, overgrowth that may involve several tissues. These disorders, which p...

    Authors: Alice Maguolo, Franco Antoniazzi, Alice Spano, Elena Fiorini, Rossella Gaudino, Margherita Mauro, Gaetano Cantalupo, Paolo Biban, Silvia Maitz and Paolo Cavarzere

    Citation: Italian Journal of Pediatrics 2018 44:110

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  6. Content type: Review

    Globally Less than one fourth of children aged 6–23 months get the recommended minimum dietary diversity feeding practice. Despite this issue is common in Ethiopia, fragmented and inconsistent findings were fo...

    Authors: Habtamu Temesgen, Ayenew Negesse, Wubetu Woyraw and Nakachew Mekonnen

    Citation: Italian Journal of Pediatrics 2018 44:109

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  7. Content type: Research

    Anemia is a public health problem affecting both developed and developing countries. Childhood anemia is associated with serious consequences including growth retardation, impaired motor and cognitive developm...

    Authors: Mulugeta Melku, Kefyalew Addis Alene, Betelihem Terefe, Bamlaku Enawgaw, Belete Biadgo, Molla Abebe, Kindie Fentahun Muchie, Asemarie Kebede, Tadele Melak and Tsedalu Melku

    Citation: Italian Journal of Pediatrics 2018 44:107

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  8. Content type: Research

    In adult studies the MTHFR C677T polymorphism has been associated with an increased risk of migraine, but little research has been done in this area in children.

    Authors: A. Orsini, I. Sammartino, A. Valetto, V. Bertini, P. Marchese, A. Bonuccelli and D. G. Peroni

    Citation: Italian Journal of Pediatrics 2018 44:106

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  9. Content type: Review

    The primary purpose of these practical guidelines related to Kawasaki disease (KD) is to contribute to prompt diagnosis and appropriate treatment on the basis of different specialists’ contributions in the fie...

    Authors: Alessandra Marchesi, Isabella Tarissi de Jacobis, Donato Rigante, Alessandro Rimini, Walter Malorni, Giovanni Corsello, Grazia Bossi, Sabrina Buonuomo, Fabio Cardinale, Elisabetta Cortis, Fabrizio De Benedetti, Andrea De Zorzi, Marzia Duse, Domenico Del Principe, Rosa Maria Dellepiane, Livio D’Isanto…

    Citation: Italian Journal of Pediatrics 2018 44:102

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  10. Content type: Review

    This second part of practical Guidelines related to Kawasaki disease (KD) has the goal of contributing to prompt diagnosis and most appropriate treatment of KD resistant forms and cardiovascular complications,...

    Authors: Alessandra Marchesi, Isabella Tarissi de Jacobis, Donato Rigante, Alessandro Rimini, Walter Malorni, Giovanni Corsello, Grazia Bossi, Sabrina Buonuomo, Fabio Cardinale, Elisabetta Cortis, Fabrizio De Benedetti, Andrea De Zorzi, Marzia Duse, Domenico Del Principe, Rosa Maria Dellepiane, Livio D’Isanto…

    Citation: Italian Journal of Pediatrics 2018 44:103

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  11. Content type: Research

    The neonatal period is only 1/60th of the first 5 years of life but it accounts for 63% of all infant deaths and 44% of all under-five deaths in Ethiopia. Most causes of neonatal death are preventable with clean ...

    Authors: Tadese Ejigu Tafere, Mesganaw Fanthahun Afework and Alemayehu Worku Yalew

    Citation: Italian Journal of Pediatrics 2018 44:105

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  12. Content type: Research

    The introduction of Universal Newborn Hearing Screening (UNHS) programs has drastically contributed to the early diagnosis of hearing loss in children, allowing prompt intervention with significant results on ...

    Authors: Rosaria Turchetta, Guido Conti, Pasquale Marsella, Maria Patrizia Orlando, Pasqualina Maria Picciotti, Simonetta Frezza, Francesca Yoshie Russo, Alessandro Scorpecci, Maria Gloria Cammeresi, Sara Giannantonio, Antonio Greco and Massimo Ralli

    Citation: Italian Journal of Pediatrics 2018 44:104

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  13. Content type: Research

    Parenteral nutrition-associated cholestasis (PNAC) is a serious complication in preterm infants receiving prolonged parenteral nutrition. Soybean lipid emulsion (SLE) seems to have a role in its pathogenesis, ...

    Authors: Simonetta Costa, Rossella Iannotta, Luca Maggio, Giovanni Barone, Francesca Serrao and Giovanni Vento

    Citation: Italian Journal of Pediatrics 2018 44:101

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  14. Content type: Review

    The relation between nasal flow and malocclusion represents a practical concern to pediatricians, otorhinolaryngologists, orthodontists, allergists and speech therapists. If naso-respiratory function may influ...

    Authors: Francesca Occasi, Ludovica Perri, Matteo Saccucci, Gabriele Di Carlo, Gaetano Ierardo, Valeria Luzzi, Giovanna De Castro, Giulia Brindisi, Lorenzo Loffredo, Marzia Duse, Antonella Polimeni and Anna Maria Zicari

    Citation: Italian Journal of Pediatrics 2018 44:100

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  15. Content type: Research

    Continuous glucose monitoring using subcutaneous sensors is useful in the management of glucose control in neonatal intensive care. We evaluated feasibility and reliability of a continuous glucose monitoring s...

    Authors: Alessandro Perri, Lucia Giordano, Mirta Corsello, Francesca Priolo, Giovanni Vento, Enrico Zecca and Eloisa Tiberi

    Citation: Italian Journal of Pediatrics 2018 44:99

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  16. Content type: Research

    Congenital space-occupying thoracic malformations and diaphragmatic hernia have in common pulmonary hypoplasia. Our study aims to assess cardiac involvement during post-natal adaptation.

    Authors: Ingrid Anne Mandy Schierz, Mario Giuffrè, Ettore Piro, Maria Clara Leone, Giuseppa Pinello and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2018 44:98

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  17. Content type: Research

    In the sub-Saharan countries, many of the children including found in health facilities are not having sufficient care of diarrhea. Diarrheal disease in these countries is one of the main causes of deaths for ...

    Authors: Atalay Getachew, Alebachew Tadie, Mulat G.Hiwot, Tadesse Guadu, Daniel Haile, Teklay G.Cherkos, Zemichael Gizaw and Marta Alemayehu

    Citation: Italian Journal of Pediatrics 2018 44:95

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  18. Content type: Research

    Henoch-Schönlein purpura nephritis (HSPN) is the most common pediatric secondary glomerular disease. This study aimed to investigate the significance of glomerular fibrinogen (Fib) deposition in children with ...

    Authors: Fengying Wang, Lusheng Huang, Hangyun Tang, Xiaozhong Li, Xueming Zhu and Xingdong Wang

    Citation: Italian Journal of Pediatrics 2018 44:97

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  19. Content type: Research

    Human milk (HM) is the best feeding for premature infants. When own mother’s milk (OMM) is insufficient or unavailable, pasteurized donor human milk (PDHM) and preterm formula (PF) are the alternative nutritio...

    Authors: Simonetta Costa, Luca Maggio, Giovanni Alighieri, Giovanni Barone, Francesco Cota and Giovanni Vento

    Citation: Italian Journal of Pediatrics 2018 44:96

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  20. Content type: Research

    In childhood B-precursor acute lymphoblastic leukemia (B-ALL), the ETV6/RUNX1 fusion transcript is considered to have an excellent outcome. However, few studies of children with ETV6/RUNX1-positive ALL from China...

    Authors: Yu Wang, Hui-min Zeng and Le-ping Zhang

    Citation: Italian Journal of Pediatrics 2018 44:94

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  21. Content type: Research

    It has been shown that approximately half of survivors of childhood acute lymphoblastic leukemia (ALL) have symptomatic late effects (LE) that may be severe or life-threatening. The aim of our study was to ass...

    Authors: Kinga Kwiecinska, Wojciech Strojny, Danuta Pietrys, Miroslaw Bik-Multanowski, Maciej Siedlar, Walentyna Balwierz and Szymon Skoczen

    Citation: Italian Journal of Pediatrics 2018 44:92

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  22. Content type: Case report

    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a serious life-treating condition characterized by skin eruption, fever, haematologic abnormalities, and multi-organ involvement that c...

    Authors: Massimo Luca Castellazzi, Susanna Esposito, Laura Elisabetta Claut, Valeria Daccò and Carla Colombo

    Citation: Italian Journal of Pediatrics 2018 44:93

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  23. Content type: Case report

    Cobalamin C (cblC) defect is the most common inborn error of Vitamin B12 metabolism often causing severe neurological, renal, gastrointestinal and hematological symptoms. Onset with pulmonary hypertension (PAH...

    Authors: Luciano De Simone, Laura Capirchio, Rosa Maria Roperto, Paola Romagnani, Michele Sacchini, Maria Alice Donati and Maurizio de Martino

    Citation: Italian Journal of Pediatrics 2018 44:90

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  24. Content type: Research

    Losing a child is devastating for parents and grandparents. Family and friends generally focus on comforting and supporting the bereaved parents, unintentionally ignoring the bereaved grandparents. Grandmother...

    Authors: JoAnne M. Youngblut and Dorothy Brooten

    Citation: Italian Journal of Pediatrics 2018 44:89

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  25. Content type: Review

    The Italian Consensus Position Statement on Diagnosis, Treatment and Prevention of Obesity in Children and Adolescents integrates and updates the previous guidelines to deliver an evidence based approach to th...

    Authors: Giuliana Valerio, Claudio Maffeis, Giuseppe Saggese, Maria Amalia Ambruzzi, Antonio Balsamo, Simonetta Bellone, Marcello Bergamini, Sergio Bernasconi, Gianni Bona, Valeria Calcaterra, Teresa Canali, Margherita Caroli, Francesco Chiarelli, Nicola Corciulo, Antonino Crinò, Procolo Di Bonito…

    Citation: Italian Journal of Pediatrics 2018 44:88

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  26. Content type: Research

    Predictors of hypovitaminosis D were extensively studied in the adult population, leading to an approximately complete understanding of them, while there is a lack of studies in the pediatric population, espec...

    Authors: Gilda Salerno, Manuela Ceccarelli, Chiara de Waure, Marianna D’Andrea, Danilo Buonsenso, Valerio Faccia, Davide Pata and Piero Valentini

    Citation: Italian Journal of Pediatrics 2018 44:86

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  27. Content type: Review

    Point-of-care ultrasonography (POCUS) allows to obtain real-time images to correlate with the patient’s presenting signs and symptoms. It can be used by various specialties and may be broadly divided into diag...

    Authors: Julien Le Coz, Silvia Orlandini, Luigi Titomanlio and Victoria Elisa Rinaldi

    Citation: Italian Journal of Pediatrics 2018 44:87

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  28. Content type: Review

    Neonatal priapism is a rare condition with only 26 described cases in literature since 1879. It is defined as a persistent penile erection occurring in the first 28 days of life, lasting at least 4 h that usua...

    Authors: Claudia Fanni, Maria Antonietta Marcialis, Maria Cristina Pintus, Cristina Loddo and Vassilios Fanos

    Citation: Italian Journal of Pediatrics 2018 44:85

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  29. Content type: Review

    Necrotizing enterocolitis continues to be a devastating disease process for very low birth weight infants in Neonatal Intensive Care Units. The aetiology and pathogenesis of necrotizing enterocolitis are not d...

    Authors: Gabriella D’Angelo, Pietro Impellizzeri, Lucia Marseglia, Angela Simona Montalto, Tiziana Russo, Ignazio Salamone, Raffaele Falsaperla, Giovanni Corsello, Carmelo Romeo and Eloisa Gitto

    Citation: Italian Journal of Pediatrics 2018 44:84

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  30. Content type: Case report

    Kikuchi-Fujimoto disease is a rare, idiopathic and generally self-limiting cause of lymphadenitis of unknow etiology with a low recurrence rate. The typical clinical signs are cervical lymphadenopathy, fever, ...

    Authors: Mara Lelii, Laura Senatore, Ilaria Amodeo, Raffaella Pinzani, Sara Torretta, Stefano Fiori, Paola Marchisio and Samantha Bosis

    Citation: Italian Journal of Pediatrics 2018 44:83

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  31. Content type: Review

    This review provides an overview of a remarkable number of significant studies in pediatrics that have been published over the past year in the Italian Journal of Pediatrics. We have selected information from ...

    Authors: Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Silvia Montella, Bertrand Tchana, Giuliana Valerio, Alberto Verrotti, Mariella Valenzise, Sergio Bernasconi and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2018 44:82

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  32. Content type: Review

    Cryptorchidism, the most common male genital abnormality observed in paediatrics, might often be associated with long-term functional consequences and can even reoccur after a successful orchidopexy. Serum mar...

    Authors: Susanna Esposito, Marta Cofini, Donato Rigante, Alberto Leonardi, Laura Lucchetti, Clelia Cipolla, Lucia Lanciotti and Laura Penta

    Citation: Italian Journal of Pediatrics 2018 44:81

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  33. Content type: Review

    Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases. In childhood, it represents a suitable therapeutic op...

    Authors: Stefania Arasi, Giovanni Corsello, Alberto Villani and Giovanni Battista Pajno

    Citation: Italian Journal of Pediatrics 2018 44:80

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  34. Content type: Review

    Anemia is one of the global public health problems affecting more than one-third of the world population. It has been strongly associated with limited psychomotor development; and poor growth and performance i...

    Authors: Mulugeta Melku, Wubet Worku Takele, Degefaye Zelalem Anlay, Daniale Tekelia Ekubagewargies, Zegeye Getaneh, Molla Abebe and Zegeye Abebe

    Citation: Italian Journal of Pediatrics 2018 44:79

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  35. Content type: Correction

    The original article [1] contained a typesetting error in Table 5; this has now been corrected.

    Authors: Antonio Pizzulli, Serena Perna, Anja Bennewiz, Holger Roeblitz, Salvatore Tripodi, Jakob Florack, Petra Wagner, Stephanie Hofmaier and Paolo Maria Matricardi

    Citation: Italian Journal of Pediatrics 2018 44:78

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    The original article was published in Italian Journal of Pediatrics 2018 44:68

  36. Content type: Letter to the Editor

    The relationship between the timing of introduction of complementary foods and later allergy is a topic of current discussion. Although the European Society for Pediatric Gastroenterology Hepatology and Nutrit...

    Authors: Elvira Verduci, Annamaria Bianchi, Marta Brambilla and Mauro Calvani

    Citation: Italian Journal of Pediatrics 2018 44:77

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  37. Content type: Research

    Newborns with congenital diaphragmatic hernia (CDH) and esophageal atresia (EA) might experience breastfeeding difficulties. The aim of this study was to detect the prevalence of breastfeeding in newborns with...

    Authors: G Salvatori, S Foligno, M Massoud, F Piersigilli, P Bagolan and A Dotta

    Citation: Italian Journal of Pediatrics 2018 44:75

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  38. Content type: Case report

    Sarcoidosis in pediatric age is uncommon and challenging diagnosis, because manifestations can be significantly variable and non-specific since it is a multisystem disease, and virtually any organ system may b...

    Authors: Mattia Giovannini, Michele Luzzati, Giovanna Ferrara, Anna Maria Buccoliero, Gabriele Simonini, Maurizio de Martino, Rolando Cimaz and Teresa Giani

    Citation: Italian Journal of Pediatrics 2018 44:74

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  39. Content type: Research

    Cystic Fibrosis (CF) Centers are involved in the decisions regarding the eligibility of CF patients with end-stage lung disease and timing for inclusion on waiting lists (WL) for lung transplantation (LT). The...

    Authors: Beatrice Borchi, Marisol Barao Ocampo, Giuseppe Cimino, Giovanna Pizzamiglio, Silvia Bresci and Cesare Braggion

    Citation: Italian Journal of Pediatrics 2018 44:72

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  40. Content type: Commentary

    Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and ...

    Authors: Alberto Berardi, Chryssoula Tzialla, Laura Travan, Jenny Bua, Daniele Santori, Milena Azzalli, Caterina Spada and Laura Lucaccioni

    Citation: Italian Journal of Pediatrics 2018 44:73

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  41. Content type: Research

    Acute mastoiditis is the main suppurative complication of acute otitis media. Its incidence ranges from 1.2 to 4.2/100.000 children/year and a rise has been reported in the last years. There are controversial ...

    Authors: Claudia Balsamo, Carlotta Biagi, Margherita Mancini, Ilaria Corsini, Rosalba Bergamaschi and Marcello Lanari

    Citation: Italian Journal of Pediatrics 2018 44:71

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  42. Content type: Research

    In previous study, we have found intermittent oral levetiracetam (LEV) can effectively prevent recurrence of febrile seizure (FS). This study aimed to analyze the effects of the preventive on the patients with...

    Authors: Lin-Yan Hu, Xiu-Yu Shi, Hui Li, Meng-Na Zhang, Shu-Fang Ma and Li-Ping Zou

    Citation: Italian Journal of Pediatrics 2018 44:70

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  43. Content type: Research

    The impact of proper aspiration of nasal secretions during upper respiratory infection on the frequency and severity of symptoms of lower airways has never been investigated. The study was aimed at testing if ...

    Authors: Antonio Pizzulli, Serena Perna, Anja Bennewiz, Holger Roeblitz, Salvatore Tripodi, Jakob Florack, Petra Wagner, Stephanie Hofmaier and Paolo Maria Matricardi

    Citation: Italian Journal of Pediatrics 2018 44:68

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    The Correction to this article has been published in Italian Journal of Pediatrics 2018 44:78

  44. Content type: Research

    High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccinati...

    Authors: Elena Bozzola, Giulia Spina, Rocco Russo, Mauro Bozzola, Giovanni Corsello and Alberto Villani

    Citation: Italian Journal of Pediatrics 2018 44:67

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  45. Content type: Research

    Young children are too often exposed to mobile devices (MD) and most of them had their own device. The adverse effects of a early and prolonged exposure to digital technology on pre-school children has been de...

    Authors: Elena Bozzola, Giulia Spina, Margherita Ruggiero, Luigi Memo, Rino Agostiniani, Mauro Bozzola, Giovanni Corsello and Alberto Villani

    Citation: Italian Journal of Pediatrics 2018 44:69

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  46. Content type: Research

    Parenteral Nutrition (PN) is prescribed to children with intestinal failure. Although life saving, complications are common. Recommendations for indications and constituents of PN are made in the 2005 guidelin...

    Authors: C. Mantegazza, N. Landy, G. V. Zuccotti and J. Köglmeier

    Citation: Italian Journal of Pediatrics 2018 44:66

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  47. Content type: Research

    Most Neonatal Intensive Care Units (NICUs) in China have restricted visiting policies for parents. This also implicates that parents are not involved in the care of their infant. Family Integrated Care (FIC), ...

    Authors: Shi-wen He, Yue-e Xiong, Li-hui Zhu, Bo Lv, Xi-rong Gao, Hua Xiong, Huan Wang, Hua-rong Shi and Jos M. Latour

    Citation: Italian Journal of Pediatrics 2018 44:65

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