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  1. Mutations in Proline-rich Transmembrane Protein 2 (PRRT2) have been primarily associated with individuals presenting with infantile epilepsy, including benign familial infantile epilepsy, benign infantile epileps...

    Authors: Piero Pavone, Giovanni. Corsello, Sung Yoon Cho, Xena Giada Pappalardo, Martino Ruggieri, Simona Domenica Marino, Dong Kyu Jin, Silvia Marino and Raffaele Falsaperla

    Citation: Italian Journal of Pediatrics 2019 45:159

    Content type: Case report

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  2. Complementary feeding from the age of 6 months along with breastfeeding is essential for the health of infants. The effect of educational interventions on preventing the early or late onset of complementary fe...

    Authors: Ziba Rafieyan-Kopaei, Zohreh Fathian-Dastgerdi, Mohammad Javad Tarrahi and Fereshteh Zamani-Alavijeh

    Citation: Italian Journal of Pediatrics 2019 45:158

    Content type: Research

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  3. Dental trauma is a frequent occurrence in children and adolescent and a correct diagnosis and treatment are essential for a favourable long-term prognosis. The present Guidelines aim to formulate evidence-base...

    Authors: Maria Grazia Cagetti, Piero Alessandro Marcoli, Mario Berengo, Piero Cascone, Livio Cordone, Patrizia Defabianis, Osvalda De Giglio, Nicola Esposito, Antonio Federici, Alberto Laino, Alessandra Majorana, Michele Nardone, Vilma Pinchi, Silvia Pizzi, Antonella Polimeni, Maria Grazia Privitera…

    Citation: Italian Journal of Pediatrics 2019 45:157

    Content type: Review

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  4. Current guidelines recommend assessing and relieving pain in all children and in all instances; yet, in clinical practice, management is frequently suboptimal. We investigated the attitude of Italian family pe...

    Authors: Gian Luigi Marseglia, Maria Alessio, Liviana Da Dalt, Maria Giuliano, Angelo Ravelli and Paola Marchisio

    Citation: Italian Journal of Pediatrics 2019 45:156

    Content type: Research

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  5. Pathogenic variants in KIF1A (kinesin family member 1A) gene have been associated with hereditary spastic paraplegia (HSP) type 30 (SPG30), encopassing autosomal dominant and recessive, pure and complicated forms...

    Authors: Carlotta Spagnoli, Susanna Rizzi, Grazia Gabriella Salerno, Daniele Frattini and Carlo Fusco

    Citation: Italian Journal of Pediatrics 2019 45:155

    Content type: Case report

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  6. Improving infant and young child feeding practices is critical to improved nutrition, health, and development of children. Ethiopia adopted the WHO recommendations of child feeding practices and developed the ...

    Authors: Zegeye Abebe, Amare Tariku, Gashaw Andargie Bikes, Molla Mesele Wassie, Kedir Abdela Gonete, Tadesse Awoke, Ejigu Gebeye, Azeb Atnafu Gete, Melkie Edris Yesuf, Yigzaw Kebede, Kassahun Alemu, Abebaw Addis, Esmael Ali Muhammad, Solomon Mekonnen Abebe, Aysheshim Kasahun belew, Melkamu Tamir Hunegnaw…

    Citation: Italian Journal of Pediatrics 2019 45:154

    Content type: Research

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  7. Teenage childbearing among adolescents aged 15 to 19 is a common sexual and reproductive health (SRH) issue among young people, particularly in developing countries. It is associated with higher maternal and n...

    Authors: Getachew Mullu Kassa, Ayodele O. Arowojolu, Akin-Tunde Ademola Odukogbe and Alemayehu Worku Yalew

    Citation: Italian Journal of Pediatrics 2019 45:153

    Content type: Research

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  8. Two hundred seventy-five thousand maternal deaths, 2.7 million neonatal deaths, and 2.6 million stillbirths have been estimated in 2015 worldwide, almost all in low-income countries (LICs). Moreover, more than...

    Authors: Gregorio Serra, Vincenzo Miceli, Salvatore Albano and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:152

    Content type: Research

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  9. Severe asthma has a substantial epidemiological impact on children and biological treatments can be an option to take into account, as they target specific molecules and pathways involved in its pathogenesis. ...

    Authors: Mattia Giovannini, Francesca Mori, Simona Barni, Maurizio de Martino and Elio Novembre

    Citation: Italian Journal of Pediatrics 2019 45:151

    Content type: Review

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  10. Neonatal sepsis is one of the leading causes of neonatal morbidity and mortality. Despite implementing of different preventive interventions, the burden of neonatal sepsis is reporting in different areas of Et...

    Authors: Mulunesh Alemu, Mulatu Ayana, Hailemariam Abiy, Biniam Minuye, Wubet Alebachew and Aklilu Endalamaw

    Citation: Italian Journal of Pediatrics 2019 45:150

    Content type: Research

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  11. The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Faceb...

    Authors: Elena Bozzola, Giulia Spina, Margherita Ruggiero, Davide Vecchio, Cinthia Caruso, Mauro Bozzola, Anna Maria Staiano, Rino Agostiniani, Antonello Del Vecchio, Giuseppe Banderali, Diego Peroni, Alberto Chiara, Luigi Memo, Renato Turra, Giovanni Corsello and Alberto Villani

    Citation: Italian Journal of Pediatrics 2019 45:149

    Content type: Research

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  12. Heterozygous mutations of the ACAN gene have been associated with a broad spectrum of non-lethal skeletal dysplasias, called Aggrecanopathies. We report a case of a child with severe inflammatory elbow involvemen...

    Authors: Angelo Florio, Riccardo Papa, Roberta Caorsi, Alessandro Consolaro, Roberto Gastaldi, Marco Gattorno and Paolo Picco

    Citation: Italian Journal of Pediatrics 2019 45:148

    Content type: Letter to the Editor

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  13. Breastfeeding is one of the most sensitive stages in the development of children, having many benefits for the mother and the child. The present study aimed to determine factors associated with breastfeeding i...

    Authors: Reyhaneh Rafizadeh, Zahra Heidari, Mahmood Karimy, Fereshteh Zamani-Alavijeh and Marzieh Araban

    Citation: Italian Journal of Pediatrics 2019 45:147

    Content type: Research

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  14. Determination of weight in children is an important aspect of their assessment. It has a wide range of usefulness including assessing their nutritional status and drug dose calculation. Despite its usefulness,...

    Authors: Ogochukwu N. Iloh, Benedict Edelu, Kenechukwu K. Iloh, Obianuju O. Igbokwe, Ikenna K. Ndu, Obinna C. Nduagubam, Uzoamaka C. Akubuilo, Ijeoma N. Obumneme-Anyim, Joy N. Eze and Chidiebere D. I. Osuorah

    Citation: Italian Journal of Pediatrics 2019 45:146

    Content type: Research

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  15. Hexavalent vaccines, protecting against six diseases (diphtheria, tetanus, pertussis [DTaP], poliovirus, hepatitis B virus [HBV], and Haemophilus influenzae type b [Hib], are routinely the standard of care in Eur...

    Authors: E. Chiappini, C. Petrolini, C. Caffarelli, M. Calvani, F. Cardinale, M. Duse, A. Licari, S. Manti, A. Martelli, D. Minasi, M. Miraglia Del Giudice, GB. Pajno, C. Pietrasanta, L. Pugni, MA. Tosca, F. Mosca…

    Citation: Italian Journal of Pediatrics 2019 45:145

    Content type: Review

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  16. Autism spectrum disorder is characterized by impairment in social interaction and communication along with repetitive, restricted, and stereotyped behaviors, interests and activities. It is important to detect...

    Authors: Antonia Parmeggiani, Arianna Corinaldesi and Annio Posar

    Citation: Italian Journal of Pediatrics 2019 45:144

    Content type: Research

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  17. Evidence of kidney damage is observed in children with sickle cell anaemia (SCA) and this continues through adulthood with progression to severe functional impairment in some. One of the earliest features of k...

    Authors: I. E. Ocheke, S. Mohamed, E. S. Okpe, F. Bode-Thomas and M. I. McCullouch

    Citation: Italian Journal of Pediatrics 2019 45:143

    Content type: Research

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  18. Heterotopic pancreas, that is the abnormal localization of a well-differentiated pancreatic tissue, is a rare occurrence in pediatric patients. Most lesions are found incidentally; in some circumstances, the p...

    Authors: Giorgio Persano, Noemi Cantone, Elisa Pani, Enrico Ciardini and Bruno Noccioli

    Citation: Italian Journal of Pediatrics 2019 45:142

    Content type: Research

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  19. Birth weight and leptin seem to be the factors responsible for early programming of body weight in later life. A marker for leptin action is free leptin index (FLI), which depends on soluble leptin receptor (O...

    Authors: Beata Kulik-Rechberger, Anna Maria Bury, Anna Rakuś-Kwiatosz and Iwona Beń-Skowronek

    Citation: Italian Journal of Pediatrics 2019 45:141

    Content type: Research

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  20. Preterm infants have immature gastrointestinal tracts and poor immunity. In this study, the effects of Lactobacillus reuteri DSM 17938 first on early feeding tolerance, growth, and second on infection prevention ...

    Authors: Xuewei Cui, Yongyan Shi, Siyang Gao, Xindong Xue and Jianhua Fu

    Citation: Italian Journal of Pediatrics 2019 45:140

    Content type: Research

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  21. The only pharmacologic prophylaxis against respiratory syncytial virus (RSV) infection in preterm infants is the humanized monoclonal antibody palivizumab. After the 2014 modification of the American Academy o...

    Authors: Renato Cutrera, Andrea Wolfler, Simonetta Picone, Giovanni A. Rossi, Giuliana Gualberti, Rocco Merolla, Antonio Del Vecchio, Alberto Villani, Fabio Midulla and Andrea Dotta

    Citation: Italian Journal of Pediatrics 2019 45:139

    Content type: Review

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  22. 17q11.2 microdeletions, which include the neurofibromatosis type 1 (NF1) gene region, are responsible for the NF1 microdeletion syndrome, observed in 4.2% of all NF1 patients. Large deletions of the NF1 gene and ...

    Authors: Gregorio Serra, Vincenzo Antona, Giovanni Corsello, Federico Zara, Ettore Piro and Raffaele Falsaperla

    Citation: Italian Journal of Pediatrics 2019 45:138

    Content type: Case report

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  23. In the era of highly active antiretroviral therapy, vertical HIV transmission has been decreased. This may increase fertility desire of HIV infected women and an increasing number of HIV exposed infants as a r...

    Authors: Chalachew Adugna Wubneh, Aklilu Endalamaw and Nigusie Birhan Tebeje

    Citation: Italian Journal of Pediatrics 2019 45:137

    Content type: Research

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  24. Despite the available interventions to tackle nutritional problems, there is scarce information on time to recovery and its determinants among children with SAM in Ethiopia.

    Authors: Worku Nigussu Mamo, Terefe Derso, Kassahun Alemu Gelaye and Temesgen Yihunie Akalu

    Citation: Italian Journal of Pediatrics 2019 45:136

    Content type: Research

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  25. Systemic chronic active Epstein-Barr virus infection is an extremely rare childhood disease. Since chronic active Epstein-Barr virus infection can trigger the onset of Epstein-Barr virus-associated lymphoproli...

    Authors: Lingling Xu, Hongjun Ba, Hongrong Lin, Liangying Zhong, Suping Li, Wen Tang, Zhiyong Ke and Ziyin Ye

    Citation: Italian Journal of Pediatrics 2019 45:135

    Content type: Case report

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  26. Around the age of 6 months, difficulties in settling to sleep and frequent night awakenings are generally occurring in 20 to 30% of infants. According to the transactional model parental factors can play a sig...

    Authors: Benedetta Ragni, Simona De Stasio, Daniela Barni, Simonetta Gentile and Rosaria Giampaolo

    Citation: Italian Journal of Pediatrics 2019 45:134

    Content type: Research

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  27. Invasive meningococcal disease is a serious global health threat in the world; in 2016, the European Centre for Disease Control and Prevention reported 3280 confirmed cases (including 304 deaths) of Invasive M...

    Authors: L. Nicolosi, C. Rizzo, G. Castelli Gattinara, N. Mirante, E. Bellelli, C. Bianchini, V. Pansini and A. Villani

    Citation: Italian Journal of Pediatrics 2019 45:133

    Content type: Research

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  28. In this letter, the authors compare the incidence of SUDI and SIDS in the Tuscany Region to the incidence reported by Campi and Bonati in their paper “Can we still do something-and what?- for a seemingly missi...

    Authors: Raffaele Piumelli, Cinzia Arzilli, Niccolò Nassi, Marta Peruzzi, Carola-Maria Ernst and Cristina Salvatori

    Citation: Italian Journal of Pediatrics 2019 45:132

    Content type: Letter to the Editor

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  29. Neonatologist performed echocardiography (NPE) has increasingly been used to assess the hemodynamic status in neonates. Aim of this survey was to investigate the utilization of NPE in Italian neonatal intensiv...

    Authors: Iuri Corsini, Benjamim Ficial, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori and Marilena Savoia

    Citation: Italian Journal of Pediatrics 2019 45:131

    Content type: Research

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  30. Recombinant human growth hormone (rhGH) is an approved and effective treatment for short children born small for gestational age (SGA). Prevalence of children eligible for treatment as SGA is reported to be 1:...

    Authors: Gianluca Tornese, Flavia Pricci, Maria Chiara Pellegrin, Marika Villa, Daniela Rotondi, Elvira Agazio and Egidio Barbi

    Citation: Italian Journal of Pediatrics 2019 45:130

    Content type: Commentary

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  31. Familial Mediterranean Fever is a monogenic autoinflammatory disease, secondary to mutation of MEFV gene, and typically expressed with recurrent attacks of fever, serositis, rash, aphthous changes in lips and/...

    Authors: Maria Cristina Maggio, Carmelo Fabiano and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:129

    Content type: Case report

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  32. Transcatheter closure of intracardiac defects might be complicated by intravascular hemolysis. We evaluated hemolysis and its outcome after transcatheter closure of these defects.

    Authors: Hamid Amoozgar, Romeileh Soltani, Mohammadreza Edraki, Nima Mehdizadegan, Hamid Mohammadi, Gholamhossein Ajami, Mohammad Borzouee, Amir Naghshzan and Kambiz Keshavarz

    Citation: Italian Journal of Pediatrics 2019 45:128

    Content type: Research

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  33. Point prevalence surveys have been used in several studies to provide immediate and easily comparable information about antibiotic use and showed that about one third of hospitalised children had on ongoing an...

    Authors: Chiara Tersigni, Carlotta Montagnani, Patrizia D’Argenio, Marzia Duse, Susanna Esposito, Yingfen Hsia, Mike Sharland and Luisa Galli

    Citation: Italian Journal of Pediatrics 2019 45:127

    Content type: Research

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  34. This review reported notable advances in pediatrics that have been published in 2018. We have highlighted progresses in allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroe...

    Authors: Carlo Caffarelli, Francesca Santamaria, Carla Mastrorilli, Angelica Santoro, Brunella Iovane, Maddalena Petraroli, Valeria Gaeta, Rosita Di Pinto, Melissa Borrelli, Sergio Bernasconi and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:126

    Content type: Review

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  35. Diagnosis of acute appendicitis (AA) and decisions about its treatment remain among the most common dilemmas of pediatric surgical teams. Monitoring of immune response may be of importance for this purpose. Ou...

    Authors: Nikola Stankovic, Maja Surbatovic, Ivan Stanojevic, Radoje Simić, Slavisa Djuricic, Maja Milickovic, Blagoje Grujic, Djordje Savic, Vesna Milojkovic Marinovic, Miona Stankovic and Danilo Vojvodic

    Citation: Italian Journal of Pediatrics 2019 45:125

    Content type: Research

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  36. We studied the short-term effects of air pollutant concentrations in Suzhou City on respiratory infections in children of different age groups.

    Authors: Dandan Zhang, Yuqin Li, Qiu Chen, Yanqun Jiang, Chu Chu, Ying Ding, Yixue Yu, Yujie Fan, Jinjin Shi, Yali Luo and Weifang Zhou

    Citation: Italian Journal of Pediatrics 2019 45:123

    Content type: Research

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  37. Melatonin has been studied and used for several years as a sleep-wake cycle modulator in patients with sleep disorders. Experimental evidence has demonstrated the multiple neuroprotective benefits of this indo...

    Authors: S. Picone, P. Ariganello, V. Mondì, F. Di Palma, L. Martini, S. Marziali, G. Fariello and P. Paolillo

    Citation: Italian Journal of Pediatrics 2019 45:122

    Content type: Research

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  38. Familial Mediterranean Fever is an autoinflammatory disease typically expressed with recurrent attacks of fever, serositis, aphthous stomatitis, rash. Only a few reports describe the association with hepatic i...

    Authors: Maria Cristina Maggio, Maria Castiglia and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:121

    Content type: Case report

    Published on:

  39. The burden of communicable diseases within developing countries is mainly influenced by poor personal hygiene practices. Hand washing is considered as most cost effective intervention for reducing health probl...

    Authors: Henok Dagne, Laekemariam Bogale, Muluneh Borcha, Anley Tesfaye and Baye Dagnew

    Citation: Italian Journal of Pediatrics 2019 45:120

    Content type: Research

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  40. Procedural sedation is increasingly needed in pediatrics. Although different drugs or drugs association are available, which is the safest and most efficient has yet to be defined, especially in syndromic chil...

    Authors: Matteo Trevisan, Sara Romano, Egidio Barbi, Irene Bruno, Flora Maria Murru and Giorgio Cozzi

    Citation: Italian Journal of Pediatrics 2019 45:119

    Content type: Case report

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  41. Pandoraea species are gram negative, motile, non-spore forming, rod shaped and oxidase positive, obligate aerobes bacteria, and have one polar flagellum. Most of Pandoraea species are associated with lung infecti...

    Authors: Mohammad Tabatabaei, Mahdi Dastbarsar and Mohammad Ashkan Moslehi

    Citation: Italian Journal of Pediatrics 2019 45:118

    Content type: Research

    Published on:

  42. Mutations in the surfactant protein C gene (SFTPC) result in interstitial lung disease (ILD). Our objective was to characterize clinical and genetic spectrum of ILD in Chinese children associated with SFTPC mutat...

    Authors: Da Hong, Dan Dai, Jing Liu, Congcong Zhang, Tingting Jin, Yanyan Shi, Gaoli Jiang, Mei Mei, Libo Wang and Liling Qian

    Citation: Italian Journal of Pediatrics 2019 45:117

    Content type: Research

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  43. Immunocompromised (IC) patients have an increased risk of refractory diarrhea. Fecal microbiota transplantation (FMT) is a safe and effective therapy for infection-related diarrhea which are mainly mediated by...

    Authors: Shuwen Zhong, Jingqing Zeng, Zhaohui Deng, Lirong Jiang, Bin Zhang, Kaihua Yang, Wenyu Wang and Tianao Zhang

    Citation: Italian Journal of Pediatrics 2019 45:116

    Content type: Case report

    Published on:

  44. Respiratory syncytial virus (RSV) is the main cause of hospitalization for bronchiolitis among infants. RSV is classified into two subtypes, A and B, whose predominance alternates during different epidemic sea...

    Authors: C. Ciarlitto, A. C. Vittucci, L. Antilici, C. Concato, C. Di Camillo, P. Zangari and A. Villani

    Citation: Italian Journal of Pediatrics 2019 45:115

    Content type: Research

    Published on:

  45. Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopt...

    Authors: Amelia Licari, Dietmar Fuchs, Gianluigi Marseglia and Giorgio Ciprandi

    Citation: Italian Journal of Pediatrics 2019 45:114

    Content type: Letter to the Editor

    Published on:

  46. In this study, we aimed to analyze differences in plasma protein abundances between infants with and without bronchopulmonary dysplasia (BPD), to add new insights into a better understanding of the pathogenesi...

    Authors: Magdalena Zasada, Maciej Suski, Renata Bokiniec, Monika Szwarc-Duma, Maria Katarzyna Borszewska-Kornacka, Józef Madej, Beata Bujak-Giżycka, Anna Madetko-Talowska, Cecilie Revhaug, Lars O. Baumbusch, Ola D. Saugstad, Jacek Józef Pietrzyk and Przemko Kwinta

    Citation: Italian Journal of Pediatrics 2019 45:112

    Content type: Research

    Published on:

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