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  1. Content type: Research

    Although Pre-lacteal feeding is a barrier for implementation of optimal breastfeeding practices and increases the risk of neonatal illness and mortality, still it is continued as a deep-rooted nutritional malp...

    Authors: Esayas Aydiko Amele, Birhanu wondimeneh Demissie, Kalkidan Wondwossen Desta and Emebet Berhane Woldemariam

    Citation: Italian Journal of Pediatrics 2019 45:15

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  2. Content type: Letter to the Editor

    Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sic...

    Authors: Gianluca Sottile, Giuliana Ferrante, Marta Torregrossa, Fabio Cibella, Giovanna Cilluffo, Salvatore Fasola, Riccardo Alessandro, Gregorio Seidita, Giovanni Viegi and Stefania La Grutta

    Citation: Italian Journal of Pediatrics 2019 45:16

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  3. Content type: Research

    Currently, severe allergic asthma and food allergy in children represent an important public health problem with medical, psychosocial and economic impacts. Omalizumab is a humanized monoclonal anti-IgE antibo...

    Authors: Giuseppe Crisafulli, Lucia Caminiti, Fernanda Chiera, Stefania Arasi, Giuseppina Salzano, Ilenia Panasiti, Andrea Barbalace and Giovanni Battista Pajno

    Citation: Italian Journal of Pediatrics 2019 45:13

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  4. Content type: Research

    Malnutrition constitutes one of the major public health challenges throughout the developing world. Urban poverty and malnutrition have been on the rise, with an increased rate of morbidity. We herein explore ...

    Authors: Maria Vittoria De Vita, Carlo Scolfaro, Bruna Santini, Antonella Lezo, Federico Gobbi, Dora Buonfrate, Elizabeth W. Kimani-Murage, Teresiah Macharia, Milka Wanjohi, Jacopo Mattia Rovarini and Gianfranco Morino

    Citation: Italian Journal of Pediatrics 2019 45:12

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  5. Content type: Review

    Functional gastrointestinal disorders (FGIDs) are characterized by chronic/recurrent gastrointestinal symptoms not related to organic disorders. Due to the limited treatment options and to the perception of su...

    Authors: Elena Scarpato, Renata Auricchio, Francesca Penagini, Angelo Campanozzi, Gian Vincenzo Zuccotti and Riccardo Troncone

    Citation: Italian Journal of Pediatrics 2019 45:9

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  6. Content type: Research

    Infants diagnosed with stage 4 s neuroblastoma commonly experience spontaneous disease regression, with few succumbing without response to therapy. We analyzed a large cohort of such infants enrolled in the It...

    Authors: Bruno De Bernardi, Andrea Di Cataldo, Alberto Garaventa, Paolo Massirio, Elisabetta Viscardi, Marta Giorgia Podda, Aurora Castellano, Paolo D’Angelo, Elisa Tirtei, Fraia Melchionda, Simona Vetrella, Francesco De Leonardis, Carmelita D’Ippolito, Annalisa Tondo, Antonella Nonnis, Giovanni Erminio…

    Citation: Italian Journal of Pediatrics 2019 45:8

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  7. Content type: Research

    Puberty can be considered the end point of a maturation process which is defined by the dynamic interactions of genes and environmental factors during prenatal and postnatal development. Kisspeptin/G protein-c...

    Authors: Nosrat Ghaemi, Martha Ghahraman, Samaneh Noroozi Asl, Rahim Vakili, Fatemeh Fardi Golyan, Meysam Moghbeli and Mohammad Reza Abbaszadegan

    Citation: Italian Journal of Pediatrics 2019 45:10

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  8. Content type: Research

    All the children of the world should be born equal, but this is not so: even in Italy, there are striking differences already at birth. Neonatal and infant mortality are accurate indexes to assess the demograp...

    Authors: Silvia Simeoni, Luisa Frova and Mario De Curtis

    Citation: Italian Journal of Pediatrics 2019 45:11

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  9. Content type: Research

    Globally, more than 20 million infants are born with low birth weight. The risk of neonatal mortality among low birth weight infants is 25 to 30 times greater than neonates with birth weight  2500 g. Low birth w...

    Authors: Daniale Tekelia Ekubagewargies, Destaye Guadie Kassie and Wubet Worku Takele

    Citation: Italian Journal of Pediatrics 2019 45:7

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  10. Content type: Research

    Nutrition cares are of the main measures to save premature infants. In this regard, proper positioning is one of the key measures that is done by nurses; still there is a paucity of studies in this field and t...

    Authors: Alireza Khatony, Alireza Abdi, Batol Karimi, Abbas Aghaei and Hamidreza Saeidi Brojeni

    Citation: Italian Journal of Pediatrics 2019 45:6

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  11. Content type: Letter to the Editor

    In our letter, we comment the paper of Kounis et al., that highlights a poor-known clinical entity determined by systemic use of corticosteroids, the so-called “Kounis syndrome type I”. We appreciated and shar...

    Authors: F. Porcaro, M. G. Paglietti, A. Diamanti, F. Petreschi, A. Schiavino, V. Negro, V. Pecora, A. Fiocchi and R. Cutrera

    Citation: Italian Journal of Pediatrics 2019 45:5

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    The original article was published in Italian Journal of Pediatrics 2018 44:143

    The Case report to this article has been published in Italian Journal of Pediatrics 2017 43:104

  12. Content type: Case report

    Hepatic glycogenosis is characterized by excessive glycogen accumulation in hepatocytes and represents a complication of poor controlled type 1 diabetes. It can be caused by excessive insulin doses or recurren...

    Authors: Fortunato Lombardo, Stefano Passanisi, Albino Gasbarro, Giovanni Tuccari, Antonio Ieni and Giuseppina Salzano

    Citation: Italian Journal of Pediatrics 2019 45:3

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  13. Content type: Research

    Prematurity accounts about 1 million neonatal deaths worldwide and the second causes of both neonatal and under five-child mortality. Neonatal mortality accounts for 43% of under-five child mortality in Ethiop...

    Authors: Ayenew Engida Yismaw, Abebaw Addis Gelagay and Malede Mequanent Sisay

    Citation: Italian Journal of Pediatrics 2019 45:4

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  14. Content type: Research

    A physiologic test for estimating BPD rate has been developed by Walsh and collaborators. Actually there are not standard criteria for weaning from CPAP and/or oxygen therapy the premature babies. Aim of this ...

    Authors: Giovanni Vento, Valentina Vendettuoli, Claudia Aurilia, Milena Tana, Chiara Tirone, Alessandra Lio, Piero Giuseppe Matassa, Francesca Priolo, Piero Catenazzi, Mirta Corsello, Enrico Zecca and Fabio Mosca

    Citation: Italian Journal of Pediatrics 2019 45:2

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  15. Content type: Research

    Optimum early postnatal growth is critical for early and later health of preterm infants. Postnatal length and weight growth velocities and their associated perinatal factors in healthy late preterm infants wi...

    Authors: Li Zhang, Yan Li, Shuang Liang, Xiao-Juan Liu, Feng-Ling Kang and Gui-Mei Li

    Citation: Italian Journal of Pediatrics 2019 45:1

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  16. Content type: Case report

    Listeria monocytogenes is a gram-positive bacteria generally transmitted to humans through ingestion of contaminated food. It typically infects high risk subjects, such as pregnant women, neonates, the elderly an...

    Authors: Massimo Luca Castellazzi, Paola Marchisio and Samantha Bosis

    Citation: Italian Journal of Pediatrics 2018 44:152

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  17. Content type: Research

    Preterm birth can interrupt lung development in utero and is associated with early life factors, which adversely affects the developing respiratory system. Studies on preterm birth and asthma risk are comparat...

    Authors: Jie Zhang, Chenchao Ma, Aimin Yang, Rongqiang Zhang, Jiannan Gong and Fengfeng Mo

    Citation: Italian Journal of Pediatrics 2018 44:151

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  18. Content type: Research

    Vitamin D plays an important role in etiology of Autism Spectrum Disorders (ASDs). We aimed to evaluate the serum 25 - hydroxyl vitamin D level among children with ASDs in Ahvaz city, Iran.

    Authors: Ali Asghar Arastoo, Hesam Khojastehkia, Zahra Rahimi, Morteza Abdullatif Khafaie, Syed Ahmad Hosseini, Syed Mohammadtaghi Mansoori, Shabnam Yosefyshad, Maryam Abshirini, Noshin Karimimalekabadi and Maria Cheraghi

    Citation: Italian Journal of Pediatrics 2018 44:150

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  19. Content type: Letter to the Editor

    During the last epidemic season of bronchiolitis (S2, years 2016–2017) we performed a single Centre analysis in inborn infant of 30+ 0–32+ 6 gestational age and age < 12 months who did not receive prophylaxis wit...

    Authors: Simonetta Picone, Adele Fabiano, Davide Roma, Federico Di Palma and Piermichele Paolillo

    Citation: Italian Journal of Pediatrics 2018 44:148

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  20. Content type: Review

    Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs). Laboratory tests for identifying children ...

    Authors: Carlo Caffarelli, Fabrizio Franceschini, Davide Caimmi, Francesca Mori, Lucia Diaferio, Dora Di Mauro, Carla Mastrorilli, Stefania Arasi, Simona Barni, Paolo Bottau, Silvia Caimmi, Fabio Cardinale, Pasquale Comberiati, Giuseppe Crisafulli, Lucia Liotti, Umberto Pelosi…

    Citation: Italian Journal of Pediatrics 2018 44:147

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  21. Content type: Commentary

    Gambling disorder (GD) is a psychiatric condition and it is characterized by a maladaptive pattern of gambling behavior that persists despite negative consequences in major areas of life functioning. In Italy,...

    Authors: Pietro Ferrara, Giulia Franceschini and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2018 44:146

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  22. Content type: Commentary

    Paediatric palliative care (PPC) aim to ensure the control of symptoms and the best possible quality of life for patients whose underlying disease, characterized by an unstoppable evolution and negative progno...

    Authors: Lucia De Zen, Federico Marchetti, Egidio Barbi and Franca Benini

    Citation: Italian Journal of Pediatrics 2018 44:144

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  23. Content type: Research

    Neonatal sepsis is an inflammatory systemic syndrome, which is a major cause of morbidity and mortality in premature infants. We analyzed the expression profile data of E-MTAB-4785 to reveal the pathogenesis o...

    Authors: Li Huang, Lixing Qiao, Huan Zhu, Li Jiang and Liping Yin

    Citation: Italian Journal of Pediatrics 2018 44:145

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  24. Content type: Letter to the Editor

    Corticosteroids are widely used for the treatment of allergic reactions but paradoxically themselves may induce acute, delayed, local or systemic allergic reactions and even anaphylaxis with Kounis syndrome. T...

    Authors: Nicholas G. Kounis, Ioanna Koniari, George D. Soufras and Emmanouil Chourdakis

    Citation: Italian Journal of Pediatrics 2018 44:143

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    The Letter to the Editor to this article has been published in Italian Journal of Pediatrics 2019 45:5

  25. Content type: Review

    Different primary studies in Ethiopia showed the burden of low birth weight. However, variation among those studies was seen. This study was aimed to estimate the national prevalence and associated factors of ...

    Authors: Aklilu Endalamaw, Eshetu Haileselassie Engeda, Daniale Tekelia Ekubagewargies, Getaneh Mulualem Belay and Mekuriaw Alemayehu Tefera

    Citation: Italian Journal of Pediatrics 2018 44:141

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  26. Content type: Research

    Anaemia is the world’s second cause of disability and it affects over half of pre-school children in developing countries and at least 30–40% in industrial countries. In poorer malaria-endemic countries, anemi...

    Authors: Reindolf Anokye, Enoch Acheampong, Anthony Kwaku Edusei, Wisdom Kwadwo Mprah, Justice Ofori-Amoah, Vida Maame Kissiwaa Amoah and Vincent Ekow Arkorful

    Citation: Italian Journal of Pediatrics 2018 44:142

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  27. Content type: Case report

    Trichorhinophalangeal syndrome (TRPS) is a rare autosomal dominant disorder caused by defects involving the TRPS1 gene. It exhibits distinctive craniofacial, ectodermal and skeletal abnormalities, such as sparse ...

    Authors: Giulia Trippella, Paolo Lionetti, Sara Naldini, Francesca Peluso, Matteo Della Monica and Stefano Stagi

    Citation: Italian Journal of Pediatrics 2018 44:138

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  28. Content type: Research

    Juvenile idiopathic arthritis (JIA) is the most common pediatric chronic rheumatic disease, which requires constant follow-up over the years, due to relapses during its progression. To maintain a good quality ...

    Authors: L. Cavazzana, M. Fornili, G. Filocamo, C. Agostoni, F. Auxilia and S. Castaldi

    Citation: Italian Journal of Pediatrics 2018 44:139

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  29. Content type: Research

    Kawasaki disease (KD) is sometimes confused with urinary tract infection (UTI) because both can present with pyuria and C-reactive protein (CRP) elevation. The present study investigated the clinical and labor...

    Authors: Seung Beom Han and Soo-Young Lee

    Citation: Italian Journal of Pediatrics 2018 44:137

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  30. Content type: Case report

    West Nile virus (WNV) is a mosquito-borne RNA virus belonging to the Flaviviridae family. Symptomatic infection happens in only about 20% of the cases, while WNV neuroinvasive disease (WNND) is rare and accounts ...

    Authors: Salvatore Savasta, Francesca Rovida, Thomas Foiadelli, Anna Maria Campana, Elena Percivalle, Gian Luigi Marseglia and Fausto Baldanti

    Citation: Italian Journal of Pediatrics 2018 44:140

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  31. Content type: Commentary

    Aim of this survey is to review the few available literature data on pathophysiologic and clinical aspects of pubertal development in boys with McCune-Albright syndrome (MAS). On the basis of such analysis, we...

    Authors: Tommaso Aversa, Giuseppina Zirilli, Domenico Corica, Filippo De Luca and Malgorzata Wasniewska

    Citation: Italian Journal of Pediatrics 2018 44:136

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  32. Content type: Review

    Newborn screening (NBS) methods and therapeutic options have become increasingly available for mucopolysaccharidoses (MPS), and there is a clear evidence that early intervention significantly improves the outc...

    Authors: Maria Alice Donati, Elisabetta Pasquini, Marco Spada, Giulia Polo and Alberto Burlina

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):126

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    This article is part of a Supplement: Volume 44 Supplement 2

  33. Content type: Review

    Mucopolysaccharidoses (MPS) are a group of lysosomal multisystemic, chronic, and progressive diseases characterized by the storage of glycosaminoglycans (GAGs) that may affect the central nervous system. Neuro...

    Authors: Rita Barone, Alessandra Pellico, Annarita Pittalà and Serena Gasperini

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):121

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    This article is part of a Supplement: Volume 44 Supplement 2

  34. Content type: Review

    Patients suffering from mucopolysaccharidosis are among the most complex from the anesthesiological point of view, especially regarding the management of the airway. The evidence base for anesthesia management...

    Authors: Alessandra Moretto, Maria Grazia Bosatra, Laura Marchesini and Simonetta Tesoro

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):116

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    This article is part of a Supplement: Volume 44 Supplement 2

  35. Content type: Review

    Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by a deficiency in lysosomal enzymes catalyzing the stepwise degradation of glycosaminoglycans (GAGs). The current therapeutic stra...

    Authors: Alessandro Fraldi, Marta Serafini, Nicolina Cristina Sorrentino, Bernhard Gentner, Alessandro Aiuti and Maria Ester Bernardo

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):130

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    This article is part of a Supplement: Volume 44 Supplement 2

  36. Content type: Review

    Mucopolysaccharidoses (MPS) are rare inherited disorders caused by a deficit of the lysosomal hydrolases involved in the degradation of mucopolysaccharides, also known as glycosaminoglycans (GAGs). They are al...

    Authors: Mirella Filocamo, Rosella Tomanin, Francesca Bertola and Amelia Morrone

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):129

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    This article is part of a Supplement: Volume 44 Supplement 2

  37. Content type: Review

    Enzyme replacement therapy (ERT) is available for mucopolysaccharidosis (MPS) I, MPS II, MPS VI, and MPS IVA. The efficacy of ERT has been evaluated in clinical trials and in many post-marketing studies with a...

    Authors: Daniela Concolino, Federica Deodato and Rossella Parini

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):120

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    This article is part of a Supplement: Volume 44 Supplement 2

  38. Content type: Review

    The mucopolysaccharidoses (MPS) are a heterogeneous group of inherited metabolic disorders, each associated with a deficiency in one of the enzymes involved in glycosaminoglycan (GAG) catabolism. Over time, GA...

    Authors: Pier Marco Bianchi, Renato Gaini and Silvano Vitale

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):127

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    This article is part of a Supplement: Volume 44 Supplement 2

  39. Content type: Review

    Mucopolysaccharidoses (MPS) are a group of diseases characterized by abnormal accumulation of glycosaminoglycans (GAGs). Although there are differences among the various disease types, the osteoarticular syste...

    Authors: Andrea Borgo, Andrea Cossio, Denise Gallone, Francesca Vittoria and Marco Carbone

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):123

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    This article is part of a Supplement: Volume 44 Supplement 2

  40. Content type: Case Report

    A new patient with severe mucopolysaccharidosis (MPS) type VII is reported. Non-immune hydrops fetalis (NIHF) was diagnosed during pregnancy. At birth, he showed generalized hydrops and dysmorphic features typ...

    Authors: Francesca Furlan, Attilio Rovelli, Miriam Rigoldi, Mirella Filocamo, Barbara Tappino, Douglas Friday, Serena Gasperini, Silvana Mariani, Claudia Izzi, Maria Pia Bondioni, Cinzia Gellera, Anna Venerando, Nicoletta Villa, Maria del Carmen Rodriguez Perez, Fabio Pavan, Andrea Biondi…

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):128

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

  41. Content type: Review

    This article discusses the role of imaging modalities including radiography, multi-detector computed tomography, magnetic resonance imaging, and ultrasound in diagnosing and monitoring skeletal abnormalities i...

    Authors: Vincenzo Spina, Domenico Barbuti, Alberto Gaeta, Stefano Palmucci, Ernesto Soscia, Marco Grimaldi, Antonio Leone, Renzo Manara and Gabriele Polonara

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):118

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

  42. Content type: Review

    The mucopolysaccharidoses (MPS) are clinically similar but also heterogeneous in terms of major or minor involvement of different organs/systems, burden of disease, and rate of progression. The attenuated form...

    Authors: Miriam Rigoldi, Elena Verrecchia, Raffaele Manna and Maria Teresa Mascia

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):132

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    This article is part of a Supplement: Volume 44 Supplement 2

  43. Content type: Introduction

    Mucopolysaccharidoses (MPS) are genetic, progressive, lysosomal storage disorders affecting virtually all organs and systems. The first MPS were clinically identified about 100 years ago. Nowadays, the enzyme ...

    Authors: Rossella Parini and Andrea Biondi

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):117

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    This article is part of a Supplement: Volume 44 Supplement 2

  44. Content type: Review

    The mucopolysaccharidoses (MPS) are a heterogeneous group of in-born metabolic conditions caused by genetic defects that result in the absence or severe deficiency of one of the lysosomal hydrolases responsibl...

    Authors: Cinzia M. Bellettato and Maurizio Scarpa

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):131

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

  45. Content type: Review

    Mucopolysaccharidoses (MPS) are a group of hereditary disorders caused by lysosomal storage of glycosaminoglycans (GAGs) and characterized by a wide variability of phenotypes from severe fetal-neonatal forms t...

    Authors: Lucia Boffi, Pierluigi Russo and Giuseppe Limongelli

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):122

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

  46. Content type: Review

    Neurosurgical features of mucopolysaccharidosis (MPS) patients mainly involve the presence of cranio-vertebral junction (CVJ) abnormalities and the development of communicating hydrocephalus. CVJ pathology is ...

    Authors: Carlo Giussani, Lelio Guida, Francesco Canonico and Erik P. Sganzerla

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):119

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

  47. Content type: Review

    Mucopolysaccharidoses (MPS) are a group of rare lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) in different parts of the eye. Ocular problems are very common in MPS ...

    Authors: Alessandra Del Longo, Elena Piozzi and Fiammetta Schweizer

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):125

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    This article is part of a Supplement: Volume 44 Supplement 2

  48. Content type: Review

    Mucopolysaccharidoses (MPS) comprise a group of lysosomal disorders that are characterized by progressive, systemic clinical manifestations and a coarse phenotype. The different types, having clinical, biochem...

    Authors: Cinzia Galimberti, Annalisa Madeo, Maja Di Rocco and Agata Fiumara

    Citation: Italian Journal of Pediatrics 2018 44(Suppl 2):133

    Published on:

    This article is part of a Supplement: Volume 44 Supplement 2

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