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  1. To date, no studies on presepsin values in cord blood of term infants with risk factors for early-onset sepsis (EOS) are available, whereas only one study reported presepsin values in cord blood of preterm inf...

    Authors: Francesca Priolo, Luca Maggio, Simona Fattore, Marta Tedesco, Domenico Umberto De Rose, Alessandro Perri, Giorgia Prontera, Roberto Chioma, Annamaria Sbordone, Maria Letizia Patti and Giovanni Vento
    Citation: Italian Journal of Pediatrics 2023 49:35
  2. In Italy, the State Regions Conference on 1st August 2019 approved the Guidelines for Short-Stay Observation (SSO). At the beginning of 2022, the main Scientific Societies of the pediatric hospital emergency-urge...

    Authors: Luciano Pinto, Sonia Bianchini, Maria Antonietta Barbieri, Gabriella Cherchi, Andrea Miceli, Maria Pia Mirauda, Valeria Spica Russotto, Irene Raffaldi, Tiziana Zangardi, Domenico Perri, Rino Agostiniani, Simone Rugolotto, Fabio Cardinale, Stefania Zampogna and Annamaria Staiano
    Citation: Italian Journal of Pediatrics 2023 49:34
  3. In literature, a few reports described an association between paraneoplastic pemphigus (PNP) and Castelman’s disease (CD), but no consensus have been proposed for the diagnostic-therapeutical approach. Aim of ...

    Authors: Mariangela Irrera, Elena Bozzola, Antonello Cardoni, Rita DeVito, Andrea Diociaiuti, Maya El Hachem, Katia Girardi, Alessandra Marchesi and Alberto Villani
    Citation: Italian Journal of Pediatrics 2023 49:33
  4. Recurrent wheezing is a common clinical problem in early childhood, which is associated with significant morbidity. There is no international consensus on the management and prevention of recurrent wheezing; t...

    Authors: Yibing Zhu, Lumin Chen, Yecheng Miao, Jinying Chen, Meng Bai, Haiyan Gao, Zhirong Zhu, Yuxuan Zhang, Jianzhong Zhang, Hafiz Khuram Raza and Guanghua Liu
    Citation: Italian Journal of Pediatrics 2023 49:31
  5. Non-alcoholic fatty liver disease is associated with obesity. A subclinical inflammation state, endothelial dysfunction, and parameters related to metabolic syndrome (MetS), have been documented in children wi...

    Authors: Rosario Valle-Martos, Luis Jiménez-Reina, Ramón Cañete, Rosario Martos, Miguel Valle and María Dolores Cañete
    Citation: Italian Journal of Pediatrics 2023 49:29
  6. Vitamin D is involved in calcium homeostasis and bone metabolism, although its extra-skeletal actions are also well-known. Low serum 25(OH)D levels are common both in adults and children worldwide.

    Authors: Tiziana Galeazzi, Sara Quattrini, Dorina Pjetraj, Simona Gatti, Chiara Monachesi, Elisa Franceschini, Luisita Marinelli, Giulia N. Catassi, Elena Lionetti and Carlo Catassi
    Citation: Italian Journal of Pediatrics 2023 49:27
  7. The aim of this study is to compare the 2021–2022 bronchiolitis season to the four previous years (2017–2018, 2018–2019, 2019–2020, 2020–2021) to see if there was an anticipation of the peak, an overall increa...

    Authors: Martha Caterina Faraguna, Irene Lepri, Antonio Clavenna, Maurizio Bonati, Chiara Vimercati, Debora Sala, Alessandro Cattoni, Maria Luisa Melzi and Andrea Biondi
    Citation: Italian Journal of Pediatrics 2023 49:26
  8. Rapid and accurate identification of pathogens is very important for the treatment of Severe community-acquired pneumonia (SCAP) in children. Metagenomic Next-generation sequencing (mNGS) has been applied in t...

    Authors: Yupeng Wei, Tongqiang Zhang, Yuting Ma, Jisi Yan, Jianghua Zhan, Jun Zheng and Yongsheng Xu
    Citation: Italian Journal of Pediatrics 2023 49:25
  9. Abnormalities in position and/or branching of the aortic arch can lead to vascular rings that may cause narrowing of the tracheal lumen due to external compression, or constriction of the oesophagus, causing s...

    Authors: Federica Porcaro, Paolo Ciliberti, Francesca Petreschi, Aurelio Secinaro, Annalisa Allegorico, Antonella Coretti and Renato Cutrera
    Citation: Italian Journal of Pediatrics 2023 49:24
  10. To date, pain and anxiety are the most common symptoms reported by children who refer to pediatric emergency department. Despite it is well known that the undertreatment of this condition has some negative con...

    Authors: Martina Bevacqua, Idanna Sforzi, Silvia Bressan, Egidio Barbi and Cyril Sahyoun
    Citation: Italian Journal of Pediatrics 2023 49:23
  11. This study investigated the efficacy of the integrated blood purification mode of early haemoperfusion (HP) combined with continuous venovenous haemodiafiltration (CVVHDF) in children with severe viral encepha...

    Authors: Jun-Lin Zhao, Zhi-Yuan Wang, Shu-Jun Li, He-Kai Ma, Xue Liu, Xiao-Wen Zhan, Wei-Wei Niu and Peng Shen
    Citation: Italian Journal of Pediatrics 2023 49:21
  12. This study aimed to analyze all the patients who contacted the hospital’s pediatric poison control center (PPCC) for exposure to ibuprofen and acetaminophen, in order to assess the incidence of any adverse rea...

    Authors: Marco Marano, Marco Roversi, Flavia Severini, Claudia Memoli, Antonio Musolino, Mara Pisani, Corrado Cecchetti and Alberto Villani
    Citation: Italian Journal of Pediatrics 2023 49:20
  13. Bronchiolitis is an acute respiratory illness that is the leading cause of hospitalization in young children. This document aims to update the consensus document published in 2014 to provide guidance on the cu...

    Authors: Sara Manti, Annamaria Staiano, Luigi Orfeo, Fabio Midulla, Gian Luigi Marseglia, Chiara Ghizzi, Stefania Zampogna, Virgilio Paolo Carnielli, Silvia Favilli, Martino Ruggieri, Domenico Perri, Giuseppe Di Mauro, Guido Castelli Gattinara, Antonio D’Avino, Paolo Becherucci, Arcangelo Prete…
    Citation: Italian Journal of Pediatrics 2023 49:19
  14. Communicating the diagnosis of Down Syndrome to a couple of parents is never easy, whether before or after birth. As doctors, we must certainly rely on our own relational skills, but it is also necessary to be...

    Authors: Caterina Gori, Guido Cocchi, Luigi Tommaso Corvaglia, Giuseppe Ramacieri, Francesca Pulina, Giacomo Sperti, Valeria Cagnazzo, Francesca Catapano, Pierluigi Strippoli, Duccio Maria Cordelli and Chiara Locatelli
    Citation: Italian Journal of Pediatrics 2023 49:18
  15. Duplications of the long arm of chromosome 3 are rare, and associated to a well-defined contiguous gene syndrome known as partial trisomy 3q syndrome. It has been first described in 1966 by Falek et al., and s...

    Authors: Gregorio Serra, Vincenzo Antona, Marcello Cimador, Giorgia Collodoro, Marco Guida, Ettore Piro, Ingrid Anne Mandy Schierz, Vincenzo Verde, Mario Giuffrè and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2023 49:17
  16. Around the world, the 2019 Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised serious public health problems and major medical challenges. T...

    Authors: Valeria Dipasquale, Marco Deganello Saccomani, Angelo Di Giorgio, Salvatore Oliva, Silvia Salvatore, Caterina Strisciuglio, Renato Tambucci, Paolo Lionetti and Claudio Romano
    Citation: Italian Journal of Pediatrics 2023 49:15
  17. Infants with rule-out infections are responsible for the majority of empirical antibiotics treatment (EAT) in neonatal intensive care units (NICUs), particularly very preterm infants (VPIs). Antibiotic overuse...

    Authors: Yao Zhu, Qing Yang, Fan Wu, Jian Mao, Ling Liu, Rong Zhang, Wei Shen, Lixia Tang, Yanmei Chang, Xiuzhen Ye, Yinping Qiu, Li Ma, Rui Cheng, Hui Wu, Dongmei Chen, Zhi Zheng…
    Citation: Italian Journal of Pediatrics 2023 49:14
  18. Nutrition practices for preterm infants include phases of parenteral nutrition, gradually interrupted parenteral nutrition (transition phase), and full enteral nutrition. However, nutrition management during t...

    Authors: Na Wang, Jia Zhang, Bo Wang, Zhangbin Yu, Jun Zhang, Linlin Qu and Bin Tang
    Citation: Italian Journal of Pediatrics 2023 49:13
  19. Post-COVID condition is a new and highly debated entity that is still to be outlined in its complexity, especially in the pediatric population. In response to the article by Trapani and colleagues, we report t...

    Authors: Silvia Garazzino, Marco Denina, Giulia Pruccoli, Elisa Funiciello, Ugo Ramenghi and Franca Fagioli
    Citation: Italian Journal of Pediatrics 2023 49:12

    The original article was published in Italian Journal of Pediatrics 2022 48:83

  20. Schimke immunoosseous dysplasia (SIOD) is an ultra-rare inherited disease affecting many organ systems. Spondyloepiphyseal dysplasia, T-cell immunodeficiency and steroid resistant nephrotic syndrome are the ma...

    Authors: Jakub Zieg, Martin Bezdíčka, Michaela Němčíková, Miroslava Balaščáková, Martina Suková, Katalin Štěrbová, Karel Vondrák, Jiří Dušek and Anna Křepelová
    Citation: Italian Journal of Pediatrics 2023 49:11
  21. Telemedicine has been recognized as an integral part of the National Health Service in Italy. Telemedicine can be adopted in the diagnostic therapeutic assistance pathway and in individual assistance plans. In...

    Authors: Gianvincenzo Zuccotti, Valeria Calcaterra and Andrea Foppiani
    Citation: Italian Journal of Pediatrics 2023 49:10
  22. Eosinophilic gastrointestinal disorders (EGIDs) are chronic/remittent inflammatory diseases associated with a substantial diagnostic delay, often attributable to misdiagnosis and variable clinical presentation...

    Authors: Martina Votto, Marco Vincenzo Lenti, Annalisa De Silvestri, Francesca Bertaina, Mirko Bertozzi, Silvia Caimmi, Emanuele Cereda, Maria De Filippo, Antonio Di Sabatino, Catherine Klersy, Alessandro Raffaele, Giovanna Riccipetitoni, Gian Luigi Marseglia, Amelia Licari and Ilaria Brambilla
    Citation: Italian Journal of Pediatrics 2023 49:9
  23. Acute otitis media has become a rare cause of facial palsy in children. A high index of suspicion is essential to achieve the diagnosis and to properly treat this condition to avoid permanent neurological sequ...

    Authors: Massimo Luca Castellazzi, Sara Torretta, Giada Maria Di Pietro, Annaclara Ciabatta, Pasquale Capaccio, Luca Caschera and Paola Marchisio
    Citation: Italian Journal of Pediatrics 2023 49:8
  24. Pediatric Mastocytosis is a rare and heterogeneous disease, characterized by accumulation of mast cells in the skin (Cutaneous Mastocytosis) and/or, less frequently, in other organs, mainly liver, spleen, bone...

    Authors: Grazia Bossi, Valeria Brazzelli, Mara De Amici, Daniela Pietra, Chiara Raviola, Matteo Naso, Corrado Regalbuto, Federica Boselli, Valeria Fortina and Gian Luigi Marseglia
    Citation: Italian Journal of Pediatrics 2023 49:6
  25. Patients who experience cardiorespiratory events usually have to be moved to specialized centers to perform cardiorespiratory studies. To avoid the transfer of these patients to specialized centers, a network ...

    Authors: Cinzia Arzilli, Monica Annunziata, Carola-Maria Ernst, Marta Peruzzi, Chiara Macucci, Saverio Pochesci and Niccolò Nassi
    Citation: Italian Journal of Pediatrics 2023 49:5
  26. In children with congenital heart disease (CHD) respiratory syncytial virus (RSV) infection may have a severe course, with increased risk of morbidity and mortality, requiring hospital admission and intensive ...

    Authors: Chiara Ratti, Anna della Greca, Deborah Bertoncelli, Monica Rubini and Bertrand Tchana
    Citation: Italian Journal of Pediatrics 2023 49:4
  27. Kawasaki disease (KD) is a kind of vasculitis with unidentified etiology. Given that the current diagnosis and therapeutic strategy of KD are mainly dependent on clinical experiences, further research to explo...

    Authors: Zhengwang Wen, Yuhan Xia, Yingying Zhang, Yuxi He, Chao Niu, Rongzhou Wu, Chunxiang Zhang, Chang Jia, Xing Rong and Maoping Chu
    Citation: Italian Journal of Pediatrics 2023 49:2
  28. Corticosteroids are widely used in medicine. Few cases of central serous chorioretinopathy (CSC) have been reported following topical corticosteroid administration. We describe the first case of pediatric CSC ...

    Authors: Stefano Ranno, Liviana Fontanel, Edoardo Ruggiero, Paolo Nucci, Paolo Radice and Simone Donati
    Citation: Italian Journal of Pediatrics 2023 49:1
  29. Kawasaki disease (KD) is an acute febrile illness of unknown etiology and predictors for intravenous immunoglobulin (IVIG) resistance have been widely explored in recent decades. Neutrophil to lymphocyte plate...

    Authors: Yuyao Lu, Yunjia Tang, Bo Wang, Xuan Li, Qiuqin Xu, Hui Chu, Haitao Lv, Meihua Lu and Yiming Qin
    Citation: Italian Journal of Pediatrics 2022 48:208
  30. Developmental delay and intellectual disability represent a common pathology in general population, involving about 3% of the pediatric age population, the genetic etiology being often involved. The aim of thi...

    Authors: Diana Miclea, Sergiu Osan, Simona Bucerzan, Delia Stefan, Radu Popp, Monica Mager, Maria Puiu, Cristian Zimbru, Adela Chirita-Emandi and Camelia Alkhzouz
    Citation: Italian Journal of Pediatrics 2022 48:207
  31. Osteopathia Striata with Cranial Sclerosis (OS-CS), also known as Horan-Beighton Syndrome, is a rare genetic disease; about 90 cases have been reported to date. It is associated with mutations (heterozygous fo...

    Authors: Gregorio Serra, Vincenzo Antona, Maria Rita Di Pace, Mario Giuffrè, Giusy Morgante, Ettore Piro, Roberto Pirrello, Sergio Salerno, Ingrid Anne Mandy Schierz, Vincenzo Verde and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:206
  32. Congenital syphilis (CS) depends on the placental transmission of Treponema pallidum (TP) spirochetes from an infected mother to fetus during pregnancy. It shows a wide clinical variability with cutaneous and vis...

    Authors: Gregorio Serra, Maurizio Carta, Maria Rita Di Pace, Eleonora La Sala, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz, Alessia Vassallo, Mario Giuffrè and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:205
  33. Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder caused by the loss of paternally expressed genes in the human chromosome region 15q11.2-q13. It is characterized by severe hypotonia and ...

    Authors: Jinying Wu, Meifang Lei, Xuetao Wang, Nan Liu, Xiaowei Xu, Chunyu Gu, Yuping Yu and Wei Liu
    Citation: Italian Journal of Pediatrics 2022 48:204

    The Correction to this article has been published in Italian Journal of Pediatrics 2023 49:32

  34. Approximately 85–90% of congenital cytomegalovirus infections (cCMV) are asymptomatic. Few studies have investigated early and long-term neurodevelopmental outcomes in children with asymptomatic cCMV (acCMV), ...

    Authors: Maria Novelli, Fabio Natale, Anna Di Norcia, Arianna Boiani, Sara Temofonte, Francesca Calandriello, Cristina Zitarelli and Barbara Caravale
    Citation: Italian Journal of Pediatrics 2022 48:203
  35. The spread of knowledge on the important implications of a diagnosis of genetic disease does not correspond to a sharing of the knowledge and equal rights of children.

    Authors: Federico Marchetti and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:202
  36. Urticarial lesions develop as a result of the activation of mast cells which, through the release of mediators, influence the formation of local inflammatory infiltrates. Changes in the expression of many cyto...

    Authors: Anna Góra, Maciej Przybył, Elżbieta Świętochowska and Edyta Machura
    Citation: Italian Journal of Pediatrics 2022 48:201
  37. Here we present the Authors’ answer to the Letter written by Dr. Garazzino and Colleagues with reference to our article “Long COVID-19 in children: an Italian cohort study”.

    Authors: Gianfranco Trapani, Giuseppe Verlato, Enrico Bertino, Giulia Maiocco, Roberta Vesentini, Alessia Spadavecchia, Angelica Dessì and Vassilios Fanos
    Citation: Italian Journal of Pediatrics 2022 48:200

    The Research to this article has been published in Italian Journal of Pediatrics 2022 48:83

  38. FIRES is defined as a disorder that requires a prior febrile infection starting between 2 weeks and 24 h before the onset of the refractory status epilepticus with or without fever at the onset of status epile...

    Authors: Piero Pavone, Giovanni Corsello, Umberto Raucci, Riccardo Lubrano, Enrico Parano, Martino Ruggieri, Filippo Greco, Silvia Marino and Raffaele Falsaperla
    Citation: Italian Journal of Pediatrics 2022 48:199
  39. It is reported that the adverse impact of nonpharmaceutical interventions (NPIs) on the mental health of children and adolescents may lead to psychologically related disorders during the coronavirus disease 20...

    Authors: Yaqi Tang, Shujing Ma, Gang Luo, Zhixian Ji, Shuiyan Zhao, Yue Cao and Silin Pan
    Citation: Italian Journal of Pediatrics 2022 48:198
  40. Both vasovagal syncope (VVS) and epilepsy present with transient loss of consciousness and are often difficult to identify. Hence this study aimed to explore the value of QT interval in the differentiation of ...

    Authors: Xin Wang, Shuo Wang, Haihui Xiao, Runmei Zou, Hong Cai, Liqun Liu, Fang Li, Yuwen Wang, Yi Xu and Cheng Wang
    Citation: Italian Journal of Pediatrics 2022 48:197
  41. Varicella is considered a mild and self-limiting disease, but, in some cases, it may complicate and require hospitalization. Antibiotics are not the first line therapy but in some cases are prescribed either f...

    Authors: Elena Bozzola, Silvio Marchesani, Andrea Ficari, Carla Brusco, Giulia Spina, Maria Rosaria Marchili and Stefano Guolo
    Citation: Italian Journal of Pediatrics 2022 48:196
  42. Nephrotic syndrome is the one of the commonest renal disorders in children. Children with nephrotic syndrome (NS) are at a high risk of atherosclerosis due to hyperlipidemia, hypertension. Carotid intima media...

    Authors: Ashraf Sayed Kamel, Mohamed Mohamed Ezzat AlGhawass, Muhammad Adel Sayed and Sara Aly Roby
    Citation: Italian Journal of Pediatrics 2022 48:195
  43. COVID-19 had devastating effects on children’s and adolescents’ life, including neuropsychological impairment, discontinuation of social life and education.

    Authors: Vita Cupertino, Elena Bozzola, Giampaolo De Luca, Emanuela Del Giudice, Giuseppe De Martino, Piero Cannataro, Alberto Eugenio Tozzi and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:194

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