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  1. Autism spectrum disorder is characterized by impairment in social interaction and communication along with repetitive, restricted, and stereotyped behaviors, interests and activities. It is important to detect...

    Authors: Antonia Parmeggiani, Arianna Corinaldesi and Annio Posar

    Citation: Italian Journal of Pediatrics 2019 45:144

    Content type: Research

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  2. Evidence of kidney damage is observed in children with sickle cell anaemia (SCA) and this continues through adulthood with progression to severe functional impairment in some. One of the earliest features of k...

    Authors: I. E. Ocheke, S. Mohamed, E. S. Okpe, F. Bode-Thomas and M. I. McCullouch

    Citation: Italian Journal of Pediatrics 2019 45:143

    Content type: Research

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  3. Heterotopic pancreas, that is the abnormal localization of a well-differentiated pancreatic tissue, is a rare occurrence in pediatric patients. Most lesions are found incidentally; in some circumstances, the p...

    Authors: Giorgio Persano, Noemi Cantone, Elisa Pani, Enrico Ciardini and Bruno Noccioli

    Citation: Italian Journal of Pediatrics 2019 45:142

    Content type: Research

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  4. Birth weight and leptin seem to be the factors responsible for early programming of body weight in later life. A marker for leptin action is free leptin index (FLI), which depends on soluble leptin receptor (O...

    Authors: Beata Kulik-Rechberger, Anna Maria Bury, Anna Rakuś-Kwiatosz and Iwona Beń-Skowronek

    Citation: Italian Journal of Pediatrics 2019 45:141

    Content type: Research

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  5. Preterm infants have immature gastrointestinal tracts and poor immunity. In this study, the effects of Lactobacillus reuteri DSM 17938 first on early feeding tolerance, growth, and second on infection prevention ...

    Authors: Xuewei Cui, Yongyan Shi, Siyang Gao, Xindong Xue and Jianhua Fu

    Citation: Italian Journal of Pediatrics 2019 45:140

    Content type: Research

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  6. The only pharmacologic prophylaxis against respiratory syncytial virus (RSV) infection in preterm infants is the humanized monoclonal antibody palivizumab. After the 2014 modification of the American Academy o...

    Authors: Renato Cutrera, Andrea Wolfler, Simonetta Picone, Giovanni A. Rossi, Giuliana Gualberti, Rocco Merolla, Antonio Del Vecchio, Alberto Villani, Fabio Midulla and Andrea Dotta

    Citation: Italian Journal of Pediatrics 2019 45:139

    Content type: Review

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  7. 17q11.2 microdeletions, which include the neurofibromatosis type 1 (NF1) gene region, are responsible for the NF1 microdeletion syndrome, observed in 4.2% of all NF1 patients. Large deletions of the NF1 gene and ...

    Authors: Gregorio Serra, Vincenzo Antona, Giovanni Corsello, Federico Zara, Ettore Piro and Raffaele Falsaperla

    Citation: Italian Journal of Pediatrics 2019 45:138

    Content type: Case report

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  8. In the era of highly active antiretroviral therapy, vertical HIV transmission has been decreased. This may increase fertility desire of HIV infected women and an increasing number of HIV exposed infants as a r...

    Authors: Chalachew Adugna Wubneh, Aklilu Endalamaw and Nigusie Birhan Tebeje

    Citation: Italian Journal of Pediatrics 2019 45:137

    Content type: Research

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  9. Despite the available interventions to tackle nutritional problems, there is scarce information on time to recovery and its determinants among children with SAM in Ethiopia.

    Authors: Worku Nigussu Mamo, Terefe Derso, Kassahun Alemu Gelaye and Temesgen Yihunie Akalu

    Citation: Italian Journal of Pediatrics 2019 45:136

    Content type: Research

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  10. Systemic chronic active Epstein-Barr virus infection is an extremely rare childhood disease. Since chronic active Epstein-Barr virus infection can trigger the onset of Epstein-Barr virus-associated lymphoproli...

    Authors: Lingling Xu, Hongjun Ba, Hongrong Lin, Liangying Zhong, Suping Li, Wen Tang, Zhiyong Ke and Ziyin Ye

    Citation: Italian Journal of Pediatrics 2019 45:135

    Content type: Case report

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  11. Around the age of 6 months, difficulties in settling to sleep and frequent night awakenings are generally occurring in 20 to 30% of infants. According to the transactional model parental factors can play a sig...

    Authors: Benedetta Ragni, Simona De Stasio, Daniela Barni, Simonetta Gentile and Rosaria Giampaolo

    Citation: Italian Journal of Pediatrics 2019 45:134

    Content type: Research

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  12. Invasive meningococcal disease is a serious global health threat in the world; in 2016, the European Centre for Disease Control and Prevention reported 3280 confirmed cases (including 304 deaths) of Invasive M...

    Authors: L. Nicolosi, C. Rizzo, G. Castelli Gattinara, N. Mirante, E. Bellelli, C. Bianchini, V. Pansini and A. Villani

    Citation: Italian Journal of Pediatrics 2019 45:133

    Content type: Research

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  13. In this letter, the authors compare the incidence of SUDI and SIDS in the Tuscany Region to the incidence reported by Campi and Bonati in their paper “Can we still do something-and what?- for a seemingly missi...

    Authors: Raffaele Piumelli, Cinzia Arzilli, Niccolò Nassi, Marta Peruzzi, Carola-Maria Ernst and Cristina Salvatori

    Citation: Italian Journal of Pediatrics 2019 45:132

    Content type: Letter to the Editor

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  14. Neonatologist performed echocardiography (NPE) has increasingly been used to assess the hemodynamic status in neonates. Aim of this survey was to investigate the utilization of NPE in Italian neonatal intensiv...

    Authors: Iuri Corsini, Benjamim Ficial, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori and Marilena Savoia

    Citation: Italian Journal of Pediatrics 2019 45:131

    Content type: Research

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  15. Recombinant human growth hormone (rhGH) is an approved and effective treatment for short children born small for gestational age (SGA). Prevalence of children eligible for treatment as SGA is reported to be 1:...

    Authors: Gianluca Tornese, Flavia Pricci, Maria Chiara Pellegrin, Marika Villa, Daniela Rotondi, Elvira Agazio and Egidio Barbi

    Citation: Italian Journal of Pediatrics 2019 45:130

    Content type: Commentary

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  16. Familial Mediterranean Fever is a monogenic autoinflammatory disease, secondary to mutation of MEFV gene, and typically expressed with recurrent attacks of fever, serositis, rash, aphthous changes in lips and/...

    Authors: Maria Cristina Maggio, Carmelo Fabiano and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:129

    Content type: Case report

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  17. Transcatheter closure of intracardiac defects might be complicated by intravascular hemolysis. We evaluated hemolysis and its outcome after transcatheter closure of these defects.

    Authors: Hamid Amoozgar, Romeileh Soltani, Mohammadreza Edraki, Nima Mehdizadegan, Hamid Mohammadi, Gholamhossein Ajami, Mohammad Borzouee, Amir Naghshzan and Kambiz Keshavarz

    Citation: Italian Journal of Pediatrics 2019 45:128

    Content type: Research

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  18. Point prevalence surveys have been used in several studies to provide immediate and easily comparable information about antibiotic use and showed that about one third of hospitalised children had on ongoing an...

    Authors: Chiara Tersigni, Carlotta Montagnani, Patrizia D’Argenio, Marzia Duse, Susanna Esposito, Yingfen Hsia, Mike Sharland and Luisa Galli

    Citation: Italian Journal of Pediatrics 2019 45:127

    Content type: Research

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  19. This review reported notable advances in pediatrics that have been published in 2018. We have highlighted progresses in allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroe...

    Authors: Carlo Caffarelli, Francesca Santamaria, Carla Mastrorilli, Angelica Santoro, Brunella Iovane, Maddalena Petraroli, Valeria Gaeta, Rosita Di Pinto, Melissa Borrelli, Sergio Bernasconi and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:126

    Content type: Review

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  20. Diagnosis of acute appendicitis (AA) and decisions about its treatment remain among the most common dilemmas of pediatric surgical teams. Monitoring of immune response may be of importance for this purpose. Ou...

    Authors: Nikola Stankovic, Maja Surbatovic, Ivan Stanojevic, Radoje Simić, Slavisa Djuricic, Maja Milickovic, Blagoje Grujic, Djordje Savic, Vesna Milojkovic Marinovic, Miona Stankovic and Danilo Vojvodic

    Citation: Italian Journal of Pediatrics 2019 45:125

    Content type: Research

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  21. We studied the short-term effects of air pollutant concentrations in Suzhou City on respiratory infections in children of different age groups.

    Authors: Dandan Zhang, Yuqin Li, Qiu Chen, Yanqun Jiang, Chu Chu, Ying Ding, Yixue Yu, Yujie Fan, Jinjin Shi, Yali Luo and Weifang Zhou

    Citation: Italian Journal of Pediatrics 2019 45:123

    Content type: Research

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  22. Melatonin has been studied and used for several years as a sleep-wake cycle modulator in patients with sleep disorders. Experimental evidence has demonstrated the multiple neuroprotective benefits of this indo...

    Authors: S. Picone, P. Ariganello, V. Mondì, F. Di Palma, L. Martini, S. Marziali, G. Fariello and P. Paolillo

    Citation: Italian Journal of Pediatrics 2019 45:122

    Content type: Research

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  23. Familial Mediterranean Fever is an autoinflammatory disease typically expressed with recurrent attacks of fever, serositis, aphthous stomatitis, rash. Only a few reports describe the association with hepatic i...

    Authors: Maria Cristina Maggio, Maria Castiglia and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:121

    Content type: Case report

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  24. The burden of communicable diseases within developing countries is mainly influenced by poor personal hygiene practices. Hand washing is considered as most cost effective intervention for reducing health probl...

    Authors: Henok Dagne, Laekemariam Bogale, Muluneh Borcha, Anley Tesfaye and Baye Dagnew

    Citation: Italian Journal of Pediatrics 2019 45:120

    Content type: Research

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  25. Procedural sedation is increasingly needed in pediatrics. Although different drugs or drugs association are available, which is the safest and most efficient has yet to be defined, especially in syndromic chil...

    Authors: Matteo Trevisan, Sara Romano, Egidio Barbi, Irene Bruno, Flora Maria Murru and Giorgio Cozzi

    Citation: Italian Journal of Pediatrics 2019 45:119

    Content type: Case report

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  26. Pandoraea species are gram negative, motile, non-spore forming, rod shaped and oxidase positive, obligate aerobes bacteria, and have one polar flagellum. Most of Pandoraea species are associated with lung infecti...

    Authors: Mohammad Tabatabaei, Mahdi Dastbarsar and Mohammad Ashkan Moslehi

    Citation: Italian Journal of Pediatrics 2019 45:118

    Content type: Research

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  27. Mutations in the surfactant protein C gene (SFTPC) result in interstitial lung disease (ILD). Our objective was to characterize clinical and genetic spectrum of ILD in Chinese children associated with SFTPC mutat...

    Authors: Da Hong, Dan Dai, Jing Liu, Congcong Zhang, Tingting Jin, Yanyan Shi, Gaoli Jiang, Mei Mei, Libo Wang and Liling Qian

    Citation: Italian Journal of Pediatrics 2019 45:117

    Content type: Research

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  28. Immunocompromised (IC) patients have an increased risk of refractory diarrhea. Fecal microbiota transplantation (FMT) is a safe and effective therapy for infection-related diarrhea which are mainly mediated by...

    Authors: Shuwen Zhong, Jingqing Zeng, Zhaohui Deng, Lirong Jiang, Bin Zhang, Kaihua Yang, Wenyu Wang and Tianao Zhang

    Citation: Italian Journal of Pediatrics 2019 45:116

    Content type: Case report

    Published on:

  29. Respiratory syncytial virus (RSV) is the main cause of hospitalization for bronchiolitis among infants. RSV is classified into two subtypes, A and B, whose predominance alternates during different epidemic sea...

    Authors: C. Ciarlitto, A. C. Vittucci, L. Antilici, C. Concato, C. Di Camillo, P. Zangari and A. Villani

    Citation: Italian Journal of Pediatrics 2019 45:115

    Content type: Research

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  30. Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. Tryptophan metabolites and neopt...

    Authors: Amelia Licari, Dietmar Fuchs, Gianluigi Marseglia and Giorgio Ciprandi

    Citation: Italian Journal of Pediatrics 2019 45:114

    Content type: Letter to the Editor

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  31. In this study, we aimed to analyze differences in plasma protein abundances between infants with and without bronchopulmonary dysplasia (BPD), to add new insights into a better understanding of the pathogenesi...

    Authors: Magdalena Zasada, Maciej Suski, Renata Bokiniec, Monika Szwarc-Duma, Maria Katarzyna Borszewska-Kornacka, Józef Madej, Beata Bujak-Giżycka, Anna Madetko-Talowska, Cecilie Revhaug, Lars O. Baumbusch, Ola D. Saugstad, Jacek Józef Pietrzyk and Przemko Kwinta

    Citation: Italian Journal of Pediatrics 2019 45:112

    Content type: Research

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  32. Congenital nephrotic syndrome (CNS), which is defined as heavy proteinuria, hypoalbuminemia, hyperlipidemia and edema, is most caused by monogenic defects in structural proteins of the glomerular filtration ba...

    Authors: Liangliang Li, Zhi Yi, Hongmin Xi, Lili Ma, Hui Shao, Wenwen Wang, Hong Pan, Miaomiao Li and Hong Jiang

    Citation: Italian Journal of Pediatrics 2019 45:109

    Content type: Case report

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  33. Pentoxifylline may be an important approach to treat neonatal sepsis. However, its use has not been well established. We conduct a systematic review and meta-analysis to evaluate the efficacy of pentoxifylline...

    Authors: Jun Tian, Peifang Shen, Kaiyu Pan and Qiong Zhou

    Citation: Italian Journal of Pediatrics 2019 45:108

    Content type: Review

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  34. The treatment of patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants remains a challenge. The ability to predict which infants will respond to indomethacin could spare some from the risks of...

    Authors: Janardhan Mydam, Alok Rastogi and Zahra J. Naheed

    Citation: Italian Journal of Pediatrics 2019 45:107

    Content type: Research

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  35. Glycogen storage disease type II (GSD II) is caused by acid alpha-glucosidase (GAA) deficiency. Both infantile-onset and juvenile-onset GSD II lead to proximal muscle weakness and respiratory insufficiency and...

    Authors: Lingling Xu, Hongjun Ba, Yuxin Pei, Xueqiong Huang, Yujian Liang, Lidan Zhang, Huimin Huang, Cheng Zhang and Wen Tang

    Citation: Italian Journal of Pediatrics 2019 45:106

    Content type: Case report

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  36. Deleterious consequences of the management of respiratory distress syndrome (RDS) with invasive ventilation have led to more in-depth investigation of non-invasive ventilation (NIV) modalities. NIV has signifi...

    Authors: Dhivya Lakshmi Permall, Asfia Banu Pasha and Xiao-qing Chen

    Citation: Italian Journal of Pediatrics 2019 45:105

    Content type: Review

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  37. Vaccination represents one of the most effective means of preventing infections for the population and for the public health in general. Recently there has been a decline in vaccinations, also among healthcare...

    Authors: Carlotta Tomboloni, Chiara Tersigni, Maurizio de Martino, Donata Dini, José Rafael González-López, Filippo Festini, Stella Neri and Daniele Ciofi

    Citation: Italian Journal of Pediatrics 2019 45:104

    Content type: Research

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  38. Acute otitis media (AOM) and pharyngitis are very common infections in children and adolescents. Italy is one of the European countries with the highest rate of antibiotic prescriptions. The aim of this study ...

    Authors: E. Barbieri, D. Donà, A. Cantarutti, R. Lundin, A. Scamarcia, G. Corrao, L. Cantarutti and C. Giaquinto

    Citation: Italian Journal of Pediatrics 2019 45:103

    Content type: Research

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  39. The therapeutic strategy for children with cow’s milk allergy (CMA) consists in the elimination of cow’s milk (CM) from their diet. Donkey’s milk (DM) has been reported to be an adequate alternative, mainly to...

    Authors: Lucrezia Sarti, Mina Martini, Giovanni Brajon, Simona Barni, Federica Salari, Iolanda Altomonte, Giuseppe Ragona, Francesca Mori, Neri Pucci, Giada Muscas, Fina Belli, Franco Corrias and Elio Novembre

    Citation: Italian Journal of Pediatrics 2019 45:102

    Content type: Research

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  40. The aim of this guidance is to provide recommendations to clinicians and other interested parties on chronic urticaria in children. The Italian Society for Pediatrics (SIP), the Italian Society for Allergy and...

    Authors: Carlo Caffarelli, Francesco Paravati, Maya El Hachem, Marzia Duse, Marcello Bergamini, Giovanni Simeone, Massimo Barbagallo, Roberto Bernardini, Paolo Bottau, Filomena Bugliaro, Silvia Caimmi, Fernanda Chiera, Giuseppe Crisafulli, Cristiana De Ranieri, Dora Di Mauro, Andrea Diociaiuti…

    Citation: Italian Journal of Pediatrics 2019 45:101

    Content type: Review

    Published on:

  41. Children with chromosome translocations, concerning X chromosome, have a genetic pattern different from Turner syndrome; however, when a translocation involves the of part of X chromosome including short statu...

    Authors: Maria Cristina Maggio and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2019 45:100

    Content type: Letter to the Editor

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  42. To investigate the relationship between symptom of attention-deficit/hyperactivity disorder (ADHD) and allergic rhinitis (AR) in AR children of different genders and ages.

    Authors: Keyang Chen, Xiuxiu Zheng, Ziyue Li, Haijie Xiang, Bobei Chen and Hui Zhang

    Citation: Italian Journal of Pediatrics 2019 45:99

    Content type: Research

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  43. Low-type anorectal malformations (ARMs) are considered benign; however, in China, data regarding such conditions are limited. Thus, this study aimed to assess the middle-term bowel functions and quality of lif...

    Authors: Haiqing Zheng, Guangjian Liu, Zijian Liang, Yunpei Chen, Zhe Wen, Jiakang Yu, Xiaogang Xu, Huiying Liang and Yong Wang

    Citation: Italian Journal of Pediatrics 2019 45:98

    Content type: Research

    Published on:

  44. This article describes the detailed project aimed to realize a dedicated ground ambulance for neonatal emergency transport service (NETS). To date, the European Community rules specify requirements for the des...

    Authors: Carlo Bellini, Martina de Biasi, Maurizio Gente, Luca A. Ramenghi, Roberto Aufieri, Diego Minghetti, Silvia Pericu, Martina Cavalieri and Niccolò Casiddu

    Citation: Italian Journal of Pediatrics 2019 45:97

    Content type: Research

    Published on:

  45. Thyroid cancer (TC) in childhood is a rare disease characterized by an excellent prognosis. Thyroid nodules in children, although less common than in adults, have a greater risk of malignancies, particularly i...

    Authors: Giuseppina Zirilli, Giuseppina Salzano, Domenico Corica, Giovanni Battista Pajno, Cristina Mignosa, Giorgia Pepe, Filippo De Luca and Giuseppe Crisafulli

    Citation: Italian Journal of Pediatrics 2019 45:96

    Content type: Commentary

    Published on:

  46. Sudden unexpected postnatal collapse of presumably healthy neonates during early skin-to-skin contact is a rare, yet recognized occurrence, associated with a high risk of mortality and morbidity. A survey was ...

    Authors: Michelangelo Barbaglia, Enrico Finale, Silvia Noce, Alessandro Vigo, Cesare Arioni, Raffaella Visentin, Elisabetta Scurati-Manzoni and Andrea Guala

    Citation: Italian Journal of Pediatrics 2019 45:95

    Content type: Research

    Published on:

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