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  1. The aim of our study was to better define the clinical pattern of diencephalic syndrome, a rare but potentially lethal cause of failure to thrive in infancy. Poor weight gain or weight loss, the characteristic...

    Authors: Sandra Trapani, Barbara Bortone, Martina Bianconi, Chiara Rubino, Iacopo Sardi, Paolo Lionetti and Giuseppe Indolfi
    Citation: Italian Journal of Pediatrics 2022 48:147
  2. The practice of therapeutic hypothermia (TH) is widely used for neonatal hypoxic-ischemic encephalopathy (HIE) despite its corresponding feeding strategies are still controversial. This randomized controlled t...

    Authors: Ya Hu, Feng Chen, Xinyu Xiang, Fang Wang, Ziyu Hua and Hong Wei
    Citation: Italian Journal of Pediatrics 2022 48:146
  3. Congenital ichthyosis (CI) is a heterogeneous group of genetic disorders characterized by generalized dry skin, scaling and hyperkeratosis, often associated to erythroderma. They are rare diseases, with overal...

    Authors: Gregorio Serra, Luigi Memo, Paola Cavicchioli, Mario Cutrone, Mario Giuffrè, Maria Laura La Torre, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:145
  4. During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of ...

    Authors: Gul Yesiltepe Mutlu, Elif Eviz, Belma Haliloglu, Heves Kirmizibekmez, Fatma Dursun, Servan Ozalkak, Atilla Cayir, Beste Yuksel Sacli, Mehmet Nuri Ozbek, Huseyin Demirbilek and Sukru Hatun
    Citation: Italian Journal of Pediatrics 2022 48:144
  5. Nutrition in the first 1000 days of life is essential to ensure appropriate growth rates, prevent adverse short- and long-term outcomes, and allow physiologic neurocognitive development. Appropriate management...

    Authors: Maria Elisabetta Baldassarre, Raffaella Panza, Francesco Cresi, Guglielmo Salvatori, Luigi Corvaglia, Arianna Aceti, Maria Lorella Giannì, Nadia Liotto, Laura Ilardi, Nicola Laforgia, Luca Maggio, Paolo Lionetti, Carlo Agostoni, Luigi Orfeo, Antonio Di Mauro, Annamaria Staiano…
    Citation: Italian Journal of Pediatrics 2022 48:143
  6. From March 2020 to July 2022, in Liguria region (North-West Italy) incidence of MIS-C among pediatric patients infected by SARS-CoV-2 was 38.7/100.000, which is higher than that of myocarditis after COVID-19 v...

    Authors: Marcello Mariani, Roberta Caorsi, Alessandro Consolaro, Giacomo Brisca, Camilla Sticchi, Marco Gattorno, Elio Castagnola and Angelo Ravelli
    Citation: Italian Journal of Pediatrics 2022 48:142
  7. Cystic fibrosis (CF) is the most common inherited disease in Caucasian populations, affecting around 50,000 patients in Europe and 30,000 in United States. A mutation in CF trans-membrane conductance regulator (C...

    Authors: Vito Terlizzi, Chiara Castellani, Giovanni Taccetti and Beatrice Ferrari
    Citation: Italian Journal of Pediatrics 2022 48:141
  8. Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We unde...

    Authors: Marco Pensabene, Maria Rita Di Pace, Fabio Baldanza, Francesco Grasso, Maria Patti, Maria Sergio, Simona La Placa, Mario Giuffre’, Gregorio Serra, Alessandra Casuccio and Marcello Cimador
    Citation: Italian Journal of Pediatrics 2022 48:140
  9. Primary Synovial Chondromatosis (PSC) is a rare benign tumor of the synovial membrane in which cartilage metaplasia produces calcific loose bodies within the articular space. Only a few cases are reported in t...

    Authors: Matteo Trevisan, Luca Di Lenarda, Serena Pastore, Alessia Saccari, Gianluca Canton, Umberto Lucangelo, Andrea Taddio and Luigi Murena
    Citation: Italian Journal of Pediatrics 2022 48:139
  10. Recent research has documented the potential associations existing between the use of social media (SM) and the occurrence/development and treatment of Eating Disorders (ED). However, the literature directly a...

    Authors: Jacopo Pruccoli, Marta De Rosa, Lucia Chiasso, Annalisa Perrone and Antonia Parmeggiani
    Citation: Italian Journal of Pediatrics 2022 48:138
  11. Considering the destructive effects of malnutrition on the growth, development, and health of children and the importance of identifying the factors affecting it, the present study aimed to investigate the sta...

    Authors: Mina Maheri, Maryam Bidar, Hamidreza Farrokh-Eslamlou and Ali Sadaghianifar
    Citation: Italian Journal of Pediatrics 2022 48:137
  12. The COVID-19 pandemic has dramatically affected healthcare professionals’ lives. We investigated the potential mental health risk faced by healthcare professionals working in neonatal units in a multicentre cr...

    Authors: Luigi Gagliardi, Serena Grumi, Marzia Gentile, Roberta Cacciavellani, Giulia Placidi, Angelina Vaccaro, Claudia Maggi, Beatrice Gambi, Letizia Magi, Laura Crespin, Graziano Memmini, Marcello DeFilippo, Elena Verucci, Liliana Malandra, Laura Mele, Angelo Azzarà…
    Citation: Italian Journal of Pediatrics 2022 48:136
  13. Childhood obesity is associated with impaired Quality-of-Life (QoL), increased stigmatization and higher risk of development of depression compared to their peers. This report describes the long-term developme...

    Authors: Rasmus Møller Jørgensen, Esben Thyssen Vestergaard, Britta Kremke, Rikke Frederiksen Bahnsen, Bent Windelborg Nielsen and Jens Meldgaard Bruun
    Citation: Italian Journal of Pediatrics 2022 48:135
  14. Authors: Adriano La Vecchia, Giulio Ippolito, Vittoria Taccani, Elisabetta Gatti, Patrizia Bono, Silvia Bettocchi, Raffaella Pinzani, Claudia Tagliabue, Samantha Bosis, Paola Marchisio and Carlo Agostoni
    Citation: Italian Journal of Pediatrics 2022 48:134

    The original article was published in Italian Journal of Pediatrics 2022 48:67

  15. Arthrogryposis multiplex congenita (AMC) is a group of clinically and etiologically heterogeneous conditions, characterized by prenatal onset contractures affecting two or more joints. Its incidence is about 1...

    Authors: Gregorio Serra, Vincenzo Antona, Chiara Cannata, Mario Giuffrè, Ettore Piro, Ingrid Anne Mandy Schierz and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:133
  16. Congenital maxillomandibular syngnathia is a rare craniofacial anomaly leading to difficulties in feeding, breathing and ability to thrive. The fusion may consist of soft tissue union (synechiae) to hard tissu...

    Authors: Ingrid Anne Mandy Schierz, Salvatore Amoroso, Vincenzo Antona, Mario Giuffrè, Ettore Piro, Gregorio Serra and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2022 48:132
  17. Congenital hypothyroidism (CH) is the most frequent congenital endocrine disorder. The purpose of the present study was to evaluate the incidence and etiological classification of CH in Apulia in a three-year ...

    Authors: Simonetta Simonetti, Gabriele D’Amato, Benedetta Esposito, Mariangela Chiarito, Domenico Dentico, Tania Lorè, Roberta Cardinali, Silvia Russo, Nicola Laforgia and Maria Felicia Faienza
    Citation: Italian Journal of Pediatrics 2022 48:131
  18. The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should a...

    Authors: Michela Scalisi, Salvatore Giordano, Laura Antonella Canduscio, Maria Concetta Failla, Luca Messina, Elisa Sferrazza, Raffaella Rubino, Lucia Siracusa, Veronica Vanella, Antonio Cascio and Claudia Colomba
    Citation: Italian Journal of Pediatrics 2022 48:130
  19. We proposed to analyze thoroughly the impact of the COVID-19 lockdown (CL) in changes of profiles and in trend of the domestic accidents (DAs) in children.

    Authors: Valentina Ferro, Raffaella Nacca, Mara Pisani, Sebastian Cristaldi, Maria Francesca Faa, Maria Chiara Supino, Umberto Raucci, Antonino Reale, Marta Ciofi Degli Atti, Massimiliano Raponi, Alberto Villani and Anna Maria Musolino
    Citation: Italian Journal of Pediatrics 2022 48:129
  20. Leukoencephalopathy with vanishing white matter (VWM) is an autosomal recessive neurological disease. The physiopathology of disease is still little understood, but it seems to involve impairment in maturation...

    Authors: Ilaria Filareto, Giulia Cinelli, Ilaria Scalabrini, Elisa Caramaschi, Patrizia Bergonzini, Elisabetta Spezia, Alessandra Todeschini and Lorenzo Iughetti
    Citation: Italian Journal of Pediatrics 2022 48:128
  21. According to the latest version of the Diagnostic and Statistical Manual of Mental Disorders, somatic symptom and related disorders (SSRDs) are defined as psychopathological manifestations characterized by phy...

    Authors: Roberta Sartori, Antimo Tessitore, Aurora Della Torca and Egidio Barbi
    Citation: Italian Journal of Pediatrics 2022 48:127
  22. Quarantine and isolation measures during COVID-19 pandemic may have caused additional stress and challenged the mental health of the youth. Aim of the study is to investigate the COVID-19 pandemic impact on ne...

    Authors: Elena Bozzola, Pietro Ferrara, Giulia Spina, Alberto Villani, Marco Roversi, Massimiliano Raponi, Giovanni Corsello and Annamaria Staiano
    Citation: Italian Journal of Pediatrics 2022 48:126
  23. Neurological vertigo is a common symptom in children and adults presenting to the emergency department (ED) and its evaluation may be challenging, requiring often the intervention of different medical specialt...

    Authors: Noemi Pellegrino, Vincenzo Di Stefano, Eleonora Rotondo, Alessandro Graziosi, Marianna Gabriella Rispoli, Angelo Torrente, Antonino Lupica, Filippo Brighina, Umberto Raucci and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:125
  24. Ventricular septal defects (VSDs) are one of the leading causes of death due to cardiac anomalies during the first months of life. The prevalence of VSD in neonates is reported up to 4%. Despite the remarkable...

    Authors: Sumbal Sarwar, Shabana, Amna Tahir, Zainab Liaqat, Saher Naseer, Rani Summeya Seme, Sabahat Mehmood, Saleem Ullah Shahid and Shahida Hasnain
    Citation: Italian Journal of Pediatrics 2022 48:124
  25. Albright’s hereditary osteodystrophy (AHO) is an inherited disorder which is caused by an inactivating variant in the GNAS gene. AHO appears associated to either pseudohypoparathyroidism 1a (PHP1a) when GNAS gene...

    Authors: Qing Zhou, Bin Liang, Qing-Xian Fu, Hui Liu and Chao-Chun Zou
    Citation: Italian Journal of Pediatrics 2022 48:123
  26. With the increasing incidence of asymptomatic carriers or milder symptoms, children and adolescents are likely to become a silent source of infection. In view of the efficacy and safety of vaccines in the trea...

    Authors: Lin Wang, Wen Wen, Chen Chen, Jiake Tang, Chunyi Wang, Mengyun Zhou, Yongran Cheng, Xingwei Zhang, Mingwei Wang, Zhanhui Feng and Weiqian Wang
    Citation: Italian Journal of Pediatrics 2022 48:122
  27. Prader-Willi syndrome (PWS) is a complex disorder caused by impaired paternally expressed genes on chromosome 15q11-q13. Variable findings have been reported about the phenotypic differences among PWS genetic ...

    Authors: Lu Zhang, Xiaoliang Liu, Yunjing Zhao, Qingyi Wang, Yuanyuan Zhang, Haiming Gao, Bijun Zhang, Wanting Cui and Yanyan Zhao
    Citation: Italian Journal of Pediatrics 2022 48:121
  28. The bacterial load of the human lower respiratory tract is at least several times lower than that of the other parts of the body. This study aimed to identify the bacterial composition and colony structure of ...

    Authors: Jiawei Yao, Tao Ai, Wanmin Xia, Yinghong Fan, Cheng Xie and Lei Zhang
    Citation: Italian Journal of Pediatrics 2022 48:120
  29. E-cigarettes are devices which allow to aerosolize liquids containing nicotine or other substances. Ever since they were released on the market in 2006, the number of users have been constantly increasing, esp...

    Authors: Chiara Casamento Tumeo, Alessandra Schiavino, Maria Giovanna Paglietti, Francesca Petreschi, Alessandra Ottavianelli, Alessandro Onofri, Claudio Cherchi, Paolo Tomà and Renato Cutrera
    Citation: Italian Journal of Pediatrics 2022 48:119
  30. The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life ...

    Authors: Antonella Riva, Elisabetta Amadori, Maria Stella Vari, Alberto Spalice, Vincenzo Belcastro, Maurizio Viri, Donatella Capodiferro, Antonino Romeo, Alberto Verrotti and Pasquale Striano
    Citation: Italian Journal of Pediatrics 2022 48:118
  31. Preterm extremely low birth weight infants (ELBWi) are known to be at greater risk of developing neuropsychiatric diseases. Identifying early predictors of outcome is essential to refer patients for early inte...

    Authors: Camilla Caporali, Stefania Longo, Giovanna Tritto, Gianfranco Perotti, Camilla Pisoni, Cecilia Naboni, Barbara Gardella, Arsenio Spinillo, Federica Manzoni, Stefano Ghirardello, Renato Borgatti and Simona Orcesi
    Citation: Italian Journal of Pediatrics 2022 48:117
  32. Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodi...

    Authors: Maria Carolina Colucci, Marica Fabiana Triolo, Simona Petrucci, Flaminia Pugnaloni, Massimiliano Corsino, Melania Evangelisti, Maria Cecilia D’Asdia, Giovanni Di Nardo, Matteo Garibaldi, Gianluca Terrin and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:116
  33. It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.

    Authors: Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano and Cristina Pederiva
    Citation: Italian Journal of Pediatrics 2022 48:115
  34. Despite simple and proven cost-effective measures were available to prevent birth asphyxia; studies suggested that there has been limited progress in preventing birth asphyxia even in healthy full-term neonate...

    Authors: Masresha Asmare Techane, Tewodros Getaneh Alemu, Chalachew Adugna Wubneh, Getaneh Mulualem Belay, Tadesse Tarik Tamir, Addis Bilal Muhye, Destaye Guadie Kassie, Amare Wondim, Bewuketu Terefe, Bethelihem Tigabu Tarekegn, Mohammed Seid Ali, Beletech Fentie, Almaz Tefera Gonete, Berhan Tekeba, Selam Fisiha Kassa, Bogale Kassahun Desta…
    Citation: Italian Journal of Pediatrics 2022 48:114
  35. Studies published on gender-related differences in the gambling behavior of adolescents have focused mainly on psychological and social factors. The aim of this study was to develop separate risk factor models...

    Authors: Alessandra Buja, Milena Sperotto, Bruno Genetti, Paolo Vian, Fabio Vittadello, Elisabetta Simeoni, Chiara Zampieri and Vincenzo Baldo
    Citation: Italian Journal of Pediatrics 2022 48:113
  36. Autism spectrum disorder (ASD) is one of the serious developmental disorders that is usually diagnosed below the age of three years. Although the severity of the disease’s symptoms varies from patient to patie...

    Authors: Nader Salari, Shabnam Rasoulpoor, Shna Rasoulpoor, Shamarina Shohaimi, Sima Jafarpour, Nasrin Abdoli, Behnam Khaledi-Paveh and Masoud Mohammadi
    Citation: Italian Journal of Pediatrics 2022 48:112
  37. Cathelicidin/LL-37 plays a significant role in the human immune defense reaction. Preterm human immature organs being exposed to inflammation-induced injury was the critical denominator leading to the common p...

    Authors: Zhuxiao Ren, Wenhui Mo, Liling Yang, Jianlan Wang, Qi Zhang, Zhicheng Zhong, Wei Wei, Zhipeng Liu, Zhiping Wu, Yao Yao and Jie Yang
    Citation: Italian Journal of Pediatrics 2022 48:111
  38. Available guidelines for asthma management represent an important and suitable tool to make the entire medical process evidence-based, effective, and safe for patients. Their purpose is to help doctors and pat...

    Authors: Elio Novembre, Mattia Giovannini, Simona Barni and Francesca Mori
    Citation: Italian Journal of Pediatrics 2022 48:110
  39. The potential use of biomarkers in the diagnosis of fungal infections is a challenge. The aim of this study was to evaluate the role of a biomarker-guided antifungal stewardship program for hospitalized pediat...

    Authors: Parisa Badiee, Ali Amanati, Fatemeh Ghasemi and Hadis Jafarian
    Citation: Italian Journal of Pediatrics 2022 48:109
  40. Adolescence is characterized by emotional instability and risk-taking behaviours that can lead to, among other things, an increased risk of developing pathological video-gaming and gambling habits. The aim of ...

    Authors: Loredana Cena, Matteo Rota, Stefano Calza, Alice Trainini, Sara Zecca, Sofia Bonetti Zappa, Luisa Silvia Nodari and Alberto Stefana
    Citation: Italian Journal of Pediatrics 2022 48:108
  41. Myogenic Arthrogryposis Multiplex Congenita type 3 (AMC-3), is a rare congenital condition characterized by severe hypotonia, club feet, and multiple joint contractures often affecting both arms and legs which...

    Authors: Naglaa M. Kamal, AlaaEddin M. Alzeky, Maher R. Omair, Ruwayd A. Attar, Abdullah M. Alotaibi, Abdullah Safar, Nawal S. Alosaimi and Sara A. S. Abosabie
    Citation: Italian Journal of Pediatrics 2022 48:107
  42. The assessment of body composition is central in diagnosis and treatment of paediatric obesity, but a criterion method is not feasible in clinical practice. Even the use of bioelectrical impedance analysis (BI...

    Authors: Maria Rosaria Licenziati, Giada Ballarin, Gabriella Iannuzzo, Maria Serena Lonardo, Olivia Di Vincenzo, Arcangelo Iannuzzi and Giuliana Valerio
    Citation: Italian Journal of Pediatrics 2022 48:106
  43. Beta thalassemia major (β-TM) is a common cause of skeletal morbidity and is associated with increased bone fracture risk, particularly in inadequately transfused children. The aim of this study was to investi...

    Authors: Tanju Çelik, Özlem Sangün, Şule Ünal, Ali Balcı and Sedat Motor
    Citation: Italian Journal of Pediatrics 2022 48:105
  44. To investigate the coping strategies of a group of adolescents with somatic symptom disorder compared to non-somatic symptom disorder peers during the COVID-19 related lockdown.

    Authors: Andrea Trombetta, Laura De Nardi, Giorgio Cozzi, Luca Ronfani, Lara Bigolin, Egidio Barbi, Matteo Bramuzzo and Giuseppe Abbracciavento
    Citation: Italian Journal of Pediatrics 2022 48:104
  45. Phototherapy (PT) is the most often utilized technique for treating and preventing severe hyperbilirubinemia in the term and preterm newborns. PT's proven benefit is that it decreases the requirement for excha...

    Authors: Mai Rabie El-Sheikh, Amira Youssef Ahmed, Abd EL-Rahman Mohamed ELMashad, Ibrahim Ibrahim Talaye and Eslam El-Sayed El-Hawary
    Citation: Italian Journal of Pediatrics 2022 48:103
  46. Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although many reports have detailed a range of neurological symptoms in SARS-C...

    Authors: Martina Capponi, Bianca Laura Cinicola, Giulia Brindisi, Cristiana Alessia Guido, Maria Cristina Torcé, Anna Maria Zicari and Alberto Spalice
    Citation: Italian Journal of Pediatrics 2022 48:102
  47. Multiple gestations represent a considerable proportion of pregnancies delivering in the late preterm (LP) period. Only 30% of LP twins are due to spontaneous preterm labor and 70% are medically indicated; amo...

    Authors: Francesca Monari, Giuseppe Chiossi, Michela Ballarini, Daniela Menichini, Giancarlo Gargano, Alessandra Coscia, Dante Baronciani and Fabio Facchinetti
    Citation: Italian Journal of Pediatrics 2022 48:101
  48. In our third-level Neonatal Unit in Northern Italy, we recorded a high rate of neonatal hyperbilirubinemia requiring phototherapy in March-November 2020, during the first phase of COVID-19 pandemic, compared t...

    Authors: Alice Monzani, Valentino Remorgida and Ivana Rabbone
    Citation: Italian Journal of Pediatrics 2022 48:100
  49. Brain abscesses are uncommon but life-threatening in extremely preterm (EP, Gestational Age < 28 weeks) infants. The information of long-time follow-up is rare, but very few cases presented almost intact neura...

    Authors: Shulin Pan, Su Lin, Jing Lin, Shangqin Chen and Zhenlang Lin
    Citation: Italian Journal of Pediatrics 2022 48:99

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