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Table 2 Duration of fever in relation to antibiotic treatment (amoxicillin vs. ampicillin) and treatment setting (inpatients vs. outpatients).

From: Prediction of delayed recovery from pediatric community-acquired pneumonia

 

Amoxicillin

Ampicillin

p-value

Inpatients

Outpatients

p-value

 

(N = 59)*

(N = 21)

 

(N = 25)

(N = 69)

 

Hours (h) of fever

25.2 ± 18.6

13.4 ± 11.3

0.012

15.3 ± 13.6

25.8 ± 20.3

0.0056

   <12 h

11 (18.6)

13 (61.9)

 

14 (56.0)

13 (18.8)

 

   12-24 h

29 (49.5)

7 (33.3)

<0.0001

9 (36.0)

33 (47.8)

0.0012§

   >24 h

19 (32.2)

1 (4.8)

 

2 (8.0)

23 (33.3)

 
  1. Data are presented as means ± SD or number (percentage).
  2. Amoxicillin was administered orally, ampicillin intravenously.
  3. * Four children with oral amoxicillin-clavulanic acid included.
  4. † Age-adjusted comparison between ampicillin and amoxicillin groups: p = 0.0006; age-looking-setting-adjusted comparison between ampicillin and amoxicillin groups: p = 0.0018.
  5. § Age-adjusted comparison between inpatient and outpatient groups: p = 0.0058.