Table 3 Comparison between clinical characteristics of children admitted to the Intensive Care Unit and to the regular ward.
Variable | Admitted to ICU (11 pts) | Admitted to regular ward (189 pts) | P |
|---|---|---|---|
Age in years (range) | 3.8 (2.4-4.6) | 4.3 (0.7-7.6) | 0.834 |
Sex, M/F | 7/4 | 107/82 | 0.885 |
Pre-existing condition N° (%) | 10 (90.9) | 69 (36.5) | 0.0011 |
Asthma | 0/11 | 10/189 | 0.94 |
Other chronic lung disease | 0/11 | 11/189 | 0.88 |
Hemoglobinopathy | 1/11 | 10/189 | 0.88 |
Heart disease | 2/11 | 5/189 | 0.06 |
Neurologic disease | 5/11 | 17/189 | 0.0011 |
Cancer | 0/11 | 5/189 | 0.65 |
Immunosuppression | 0/11 | 5/189 | 0.65 |
Other | 2/11 | 6/189 | 0.09 |
Clinical signs and symptoms, N° (%) | |||
Fever | 10 (91) | 175 (92.6) | 0.702 |
Cough | 7 (63.6) | 122 (64.5) | 0.793 |
Dispnea | 8 (72.7) | 52 (27.5) | 0.0045 |
Wheezing | 5 (45.5) | 26 (13.7) | 0.0166 |
Hypoxemia at admission (Sat O2 <93%) | 8 (72.7) | 26 (13.7) | <0.0001 |
Chest pain | 0 | 6 (3.2) | 0.757 |
Rhinorrea | 4 (36.4%) | 65 (34.4) | 0.847 |
Asthenia | 6 (54.5%) | 92 (48.6) | 0.946 |
Myalgia | 0 | 7 (3.7) | 0.846 |
Abdominal Pain | 0 | 11 (5.8) | 0.886 |
Vomiting | 3 (27.3%) | 32 (17) | 0.638 |
Diarrhea | 0 | 10 (5.3) | 0.940 |
Laboratory Results (range) | |||
Leukocyte--per mmc | 5700 (4700-8380) | 8600 (5590-12075) | 0.1186 |
Neutrophils--per mmc | 73 (47-77) | 64 (39-77) | 0.607 |
CRP--mg/L | 28.5 (3-64) | 7 (2.2-25.7) | 0.137 |
Hb--g/dL | 9.8 (8.4-11.1) | 12 (11-13.2) | 0.001 |
Hb < 10 g/dL, N° (%) | 5/11 (45) | 23/189 (12) | 0.0046 |
Chest Radiograph (132 patients) | |||
Abnormal Chest X-rays, N° (%) | 11/11 (100) | 96/121 (79.3) | 0.203 |
Interstitial/focal consolidation, N° | 2/9 | 23/70 | 0.9143 |
Unilateral/Bilateral consolidation, N° | 4/5 | 55/15 | 0.0752 |
Pleural effusion, N° (%) | 1/11(9) | 4/121 (3.3) | NS |
Therapy | |||
Antiviral treatment, N° (%) | 9 (81) | 94 (50) | 0.078 |
Days from onset of symptoms to initiation | 5 (2-6.75) | 3 (1.75-5) | 0.203 |