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Table 2 Different clinical and laboratory parameters before and after iron therapy.

From: Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study

 

Obese children with IDA

Non-obese children with IDA

P value

 

(n = 35)

(n = 35)

 

BMI (kg/m2)

   

Baseline

25.70 ± 2.2

16.30 ± 1.9

<0.01

3 months after Fe therapy

25.91 ± 2.3

16.22 ± 1.2

<0.01

   p value

>0.05

>0.05

 

Hb (g/dl)

   

Baseline

8.82 ± 1.2

8.22 ± 1.4

>0.05

3 months after Fe therapy

10.1 ± 0.8

12.8 ± 0.7

<0.05

   p value

<0.05

<0.05

 

Serum iron (ug/dl)

   

Baseline

28.83 ± 2.5

29.28 ± 4.6

>0.05

3 months after Fe therapy

44.6 ± 6.9

65 ± 8.9

<0.05

   p value

<0.05

<0.05

 

TIBC (mg/dl)

   

Baseline

491 ± 24

478 ± 15

>0.05

3 months after Fe therapy

385 ± 42

210 ± 23

<0.05

   p value

<0.05

<0.05

 

Serum ferritin (ng/ml)

   

Baseline

51.91 ± 8.7

7.52 ± 1.6

<0.01

3 months after Fe therapy

52.19 ± 4.1

54.19 ± 4.1

>0.05

   p value

>0.05

<0.01

 

Serum hepcidin (nmol/L)

   

Baseline

4.96 ± 1.2

0.11 ± 0.03

<0.01

3 months after Fe therapy

4.56 ± 1.4

1.62 ± 0.6

<0.01

   p value

>0.05

<0.01

 
  1. P > 0.05 = non-significant, P < 0.05 = significant, P < 0.01 highly significant. (Student t test).