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Table 3 Keypoints in the use of montelukast in preschool children with wheezing disorders

From: Update on leukotriene receptor antagonists in preschool children wheezing disorders

Evidences Controversies
Effectiveness in episodic (viral) wheeze Effectiveness of intermittent use in severe recurrent wheeze
Effectiveness in multi-trigger wheeze Effectiveness of combined therapy with inhaled steroids in wheezing children
Reduction of airway inflammation Effectiveness in severe post-RSV bronchiolitis wheeze
Excellent safety profile Effectiveness in acute exacerbation
Good compliance due to oral single administration Selection criteria of subjects with wheezing to treat with monotherapy or combined therapyv with inhaled steroids