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Table 1 Patients’ thyroid functions, urine iodine levels and thyroid volumes

From: Thyroid functions of neonates with Down syndrome

  All cases (n = 80) Normal thyroid function (n = 37) Hyperthyrotropinemia (n = 32) p value*
  n Mean ± SD Median (min-max) n Mean ± SD Median (min-max) n Mean ± SD Median (min-max)  
TSH (mU/L) 80 24.8 ± 30.9 12.4 (0.08 ± 127.7) 37 7.1 ± 4.8 5.9 (0.08-16.2) 32 45.6 ± 33.4 34.7 (10.1-127.7) 0.001
FT4 (pg/ml) 80 13.6 ± 4.3 13.5 (5–26.4) 37 14.4 ± 3.7 14.1 (7.8-25.1) 32 12.5 ± 3.4 13.3 (7.2-22.5) 0.08
FT3 (pg/ml) 79 2.6 ± 0.9 2.5 (0.01-5.45) 36 2.6 ± 0.6 2.7 (1.1-3.8) 32 2.6 ± 1.1 2.5 (0.01-5.4) 0.84
Thyroglobulin (ng/ml) 62 102.3 ± 104.3 59.5 (1.9-510.8) 25 67.2 ± 51.9 49.4 (6.5-199) 27 142.4 ± 135.5 89.2 (4.4-510.8) 0.055
Urine iodine (μg/dl) 28 12.6 ± 12.3 10 (1–59) 3 13.6 ± 1.5 14 (12–15) 15 11.5 ± 10.3 10.2 (1–37) -
Thyroid volume (ml) 36 0.55 ± 0.27 0.51 (0.20-1.51) 8 0.43 ± 0.14 0.42 (0.24-0.63) 22 0.64 ± 0.29 0.56 (0.31-1.51) 0.01
  1. *: p values reflect the comparison values between the cases with and without hyperthyrotropinemia (normal thyroid function).