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Table 1 Patients’ thyroid functions, urine iodine levels and thyroid volumes

From: Thyroid functions of neonates with Down syndrome

 

All cases (n = 80)

Normal thyroid function (n = 37)

Hyperthyrotropinemia (n = 32)

p value*

 

n

Mean ± SD

Median (min-max)

n

Mean ± SD

Median (min-max)

n

Mean ± SD

Median (min-max)

 

TSH (mU/L)

80

24.8 ± 30.9

12.4 (0.08 ± 127.7)

37

7.1 ± 4.8

5.9 (0.08-16.2)

32

45.6 ± 33.4

34.7 (10.1-127.7)

0.001

FT4 (pg/ml)

80

13.6 ± 4.3

13.5 (5–26.4)

37

14.4 ± 3.7

14.1 (7.8-25.1)

32

12.5 ± 3.4

13.3 (7.2-22.5)

0.08

FT3 (pg/ml)

79

2.6 ± 0.9

2.5 (0.01-5.45)

36

2.6 ± 0.6

2.7 (1.1-3.8)

32

2.6 ± 1.1

2.5 (0.01-5.4)

0.84

Thyroglobulin (ng/ml)

62

102.3 ± 104.3

59.5 (1.9-510.8)

25

67.2 ± 51.9

49.4 (6.5-199)

27

142.4 ± 135.5

89.2 (4.4-510.8)

0.055

Urine iodine (μg/dl)

28

12.6 ± 12.3

10 (1–59)

3

13.6 ± 1.5

14 (12–15)

15

11.5 ± 10.3

10.2 (1–37)

-

Thyroid volume (ml)

36

0.55 ± 0.27

0.51 (0.20-1.51)

8

0.43 ± 0.14

0.42 (0.24-0.63)

22

0.64 ± 0.29

0.56 (0.31-1.51)

0.01

  1. *: p values reflect the comparison values between the cases with and without hyperthyrotropinemia (normal thyroid function).