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Table 1 Etiopathogenesis of infantile colic

From: Looking for new treatments of Infantile Colic

Main factors

Related factors

Immaturity of nervous/digestive system

Family tension

Cow’s milk proteins allergy and atopy

Maternal smoking

Altered gut microflora (low Lactobacilli, increased E.coli)

Increased maternal age

Gut hormones (increased ghrelin and motilin)

Firstborn status